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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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1

Health Effects of the Standardized Research E-Cigarette in Smokers With HIV Smokers With HIV

for
HIV
Location: Providence RI
Sponsor: Brown University

Sex: All

Age: 18+

Code: NCT03862924

Recruiting
New

Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy

for
Prostate Carcinoma
Location: Buffalo NY
Sponsor: Roswell Park Cancer Institute

Sex: Male

Age: 18+

Code: NCT07075705

Recruiting
New

A Phase 1 Dose-escalation and Expansion Study of In Vivo BCMA-CAR T Cell Therapy (VV169) in Patients With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma Refractory, Multiple Myeloma in Relapse
Location: Rochester MN
Sponsor: Vyriad, Inc.

Sex: All

Age: 18+

Code: NCT07802717

Phase1, Recruiting
New

Testing the Investigational Agent Combination of Daratumumab, Bortezomib, and Dexamethasone Compared to the Usual Treatment of Cyclophosphamide, Bortezomib, and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients With Kidney Failure

for
Myeloma Multiple
Location: Anchorage AK
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18+

Code: NCT07085728

Phase2, Recruiting

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

for
Hiv, Opioid Use Disorder
Location: New Haven CT
Sponsor: University of Connecticut

Sex: All

Age: 18+

Code: NCT05669534

Recruiting

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Inobrodib, Pomalidomide and Dexamethasone Versus Standard Available Therapy in Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma Refractory, Multiple Myeloma in Relapse
Location: Miami FL
Sponsor: CellCentric Ltd.

Sex: All

Age: 18+

Code: NCT07772024

Phase3, Recruiting

The Utilization Effects of Powered Wearable Orthotics in Improving Upper Extremity Function and ADL in Persons With SCI

for
SCI - Spinal Cord Injury, Upper Extremity Dysfunction,
Location: West Orange NJ
Sponsor: Kessler Foundation

Sex: All

Age: 18 - 70+

Code: NCT06349434

Recruiting
New

Two-photon Fluorescence Microscopy of Dermatologic Biopsies

for
Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma,
Location: Victor NY
Sponsor: University of Rochester

Sex: All

Age: 0+

Code: NCT07773688

Recruiting
New

Machine Learning Analysis of Two-photon Fluorescence Microscopy of Dermatologic Biopsies

for
Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma (Skin)
Location: Victor NY
Sponsor: University of Rochester

Sex: All

Age: 0+

Code: NCT07682831

Recruiting
New

A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Denver CO
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT04910568

Phase1, Recruiting
New

Duke APOL1 Research Biorepository

for
End Stage Kidney Disease
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT04160507

Recruiting
New

A Study of the Preliminary Efficacy of DARE-HPV to Treat High-risk Persistent Human Papillomavirus (hrHPV)

for
Human Papilloma Virus (HPV),
Location: Little Rock AR, Layton UT, Phoenix AZ, Seattle WA
Sponsor: Daré Bioscience, Inc.

Sex: Female

Age: 22 - 50

Code: NCT07601074

Phase2, Recruiting

Germ Cell Tumor and Testicular Tumor DNA Registry

for
Germ Cell Tumor, Testicular Tumor
Location: Commack NY, Harrison NY, New York NY, Middletown NJ,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT02099734

Recruiting

A Prospective Study of Conventional Bone Marrow Biopsy Versus Portomar(TM) Biopsy

for
Hematologic Malignancy
Location: Houston TX
Sponsor: Aperture Medical Technology, LLC

Sex: All

Age: 21+

Code: NCT05583734

Recruiting
New

A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma

for
Phase 1, NK Cell, IL13Ra, EGFRvIII,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07579208

Phase1, Recruiting

Studies of Disorders With Increased Susceptibility to Fungal Infections

for
Fungal Infections, Primary Immune Deficiencies
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 70+

Code: NCT01222741

Recruiting
New

Mosunetuzumab and Polatuzumab Vedotin With Split-Dose CHP Chemotherapy for Elderly Patients With Diffuse Large B-Cell Lymphoma

for
Diffuse Large B Cell Lymphoma (DLBCL)
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 70+

Code: NCT06594939

Phase2, Recruiting

Study of Treatment for HPV16+ ASC-US or LSIL

for
ASC-US, LSIL
Location: Baltimore MD, Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: Female

Age: 19+

Code: NCT03913117

Phase1, Recruiting
New

Biofluid Research on Age-Related or Inherited Neurodegeneration

for
Frontotemporal Degeneration (FTD),
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07798700

Recruiting
New

Study of SIR2501 in Solid Tumor Patients Receiving Paclitaxel

for
Chemotherapy-induced Peripheral Neuropathy
Location: Baltimore MD
Sponsor: Sironax USA, Inc.

Sex: All

Age: 18+

Code: NCT07765446

Phase2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer