Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
Active & Responsive
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
for
Chronic Hepatitis Delta
Location: Anaheim CA, La Jolla CA, Louisville KY, Baltimore MD,
Sponsor: Gilead Sciences
Sex: All
Age: 18 - 69
Code: NCT07096193
Phase1, Phase2, Recruiting
Active & ResponsiveNew
A Study of V132 in Healthy Older Participants (V132-001)
for
Healthy
Location: Anaheim CA, Lincoln NE, Omaha NE, League City TX,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 50 - 70+
Code: NCT07712575
Phase1, Recruiting
Active & Responsive
FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients
for
Healthy Participants, Atopic Dermatitis
Location: Anaheim CA, San Diego CA, Troy MI, Miami FL,
Sponsor: Pfizer
Sex: All
Age: 18 - 70
Code: NCT06564389
Phase1, Recruiting
Active & ResponsiveNew
A Study to Assess the Pharmacokinetics, Safety and Tolerability of Single-dose Adagrasib (BMS-986503) in Healthy Participants of Japanese Descent
for
Healthy Participants
Location: Anaheim CA
Sponsor: Mirati Therapeutics Inc.
Sex: All
Age: 18 - 60
Code: NCT07723118
Phase1, Recruiting
Active & Responsive
A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) and Overweight or Obesity
for
Adults With Overweight/Obesity and Type 2 Diabetes
Location: Anaheim CA, Chandler AZ, Salt Lake City UT, Atlanta GA,
Sponsor: Antag Therapeutics
Sex: All
Age: 18+
Code: NCT07724340
Phase2, Recruiting
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Active & Responsive
Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial
for
Myopia
Location: Fullerton CA, Palo Alto CA, Berkeley CA, Houston TX,
Sponsor: Ohio State University
Sex: All
Age: 6 - 11
Code: NCT07567040
Phase3, Recruiting
Active & Responsive
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
for
Overweight, Obesity
Location: Cypress CA, Overland Park KS, Montreal
Sponsor: Novo Nordisk A/S
Sex: All
Age: 18 - 65
Code: NCT07395687
Phase2, Recruiting
Active & Responsive
Study of EVO756 in Adults With Migraine
for
Migraine
Location: Buena Park CA, Los Angeles CA, Fresno CA, Chandler AZ,
Sponsor: Evommune, Inc.
Sex: All
Age: 18 - 64
Code: NCT07616128
Phase2, Recruiting
Active & Responsive
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
for
Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms,
Location: Fullerton CA, Los Angeles CA, Houston TX, Urbana IL,
Sponsor: Stemline Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT05386108
Phase1, Phase2, Recruiting
Active & Responsive
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
for
Carcinoma, Non-Small-Cell Lung
Location: Fullerton CA, Long Beach CA, Los Angeles CA, Gilbert AZ,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT06623422
Phase3, Recruiting
Active & Responsive
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
for
Breast Neoplasms
Location: Fullerton CA, Chandler AZ, Gilbert AZ, Denver CO,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT06312176
Phase3, Recruiting
Active & Responsive
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
for
Coronavirus Disease (COVID-19)
Location: Los Alamitos CA, Northridge CA, Westlake Village CA,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT06667700
Phase3, Recruiting
Active & Responsive
A Study of LY4088044 in Healthy Participants
for
Healthy
Location: Los Alamitos CA, Salt Lake City UT, San Antonio TX
Sponsor: Eli Lilly and Company
Sex: All
Age: 18 - 65
Code: NCT07090785
Phase1, Recruiting
Active & Responsive
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
for
Parkinson Disease
Location: Los Alamitos CA, Carlsbad CA, Palo Alto CA,
Sponsor: Appello Pharmaceuticals, Inc.
Sex: All
Age: 30 - 70+
Code: NCT07432958
Phase2, Recruiting
Active & Responsive
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
for
Psoriatic Arthritis, Axial Spondyloarthritis
Location: Fullerton CA, Whittier CA, Covina CA, Upland CA,
Sponsor: UCB Biopharma SRL
Sex: All
Age: 18+
Code: NCT07290036
Phase1, Recruiting
Active & ResponsiveNew
Study to Assess KN3835 in the Treatment of Flexible/Semi-Flexible Hammertoe (HMT)
for
Flexible Hammertoe, Semi-flexible Hammertoe
Location: Corona CA, Tarzana CA, Salt Lake City UT, Bedford TX,
Sponsor: Endo USA Inc., a Keenova Therapeutics Company
Sex: All
Age: 18 - 70+
Code: NCT07759362
Phase3, Recruiting
Active & Responsive
Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)
for
Alcohol Use Disorder
Location: Long Beach CA, West Los Angeles CA, Palo Alto CA,
Sponsor: VA Office of Research and Development
Sex: All
Age: 18 - 70+
Code: NCT07218354
Phase3, Recruiting
Active & Responsive
A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder
for
Opioid Use Disorder
Location: Long Beach CA, Phoenix AZ, Palo Alto CA,
Sponsor: VA Office of Research and Development
Sex: All
Age: 18+
Code: NCT04375033
Recruiting
Active & Responsive
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response
for
Chronic Low Back Pain
Location: Long Beach CA, Loma Linda CA, Phoenix AZ, Palo Alto CA,
Sponsor: VA Office of Research and Development
Sex: All
Age: 18+
Code: NCT04142177
Recruiting
Active & Responsive
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD