Discover 3,581 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,581
Active & Responsive
A Study of Zasocitinib in Adults With Nonsegmental Vitiligo
for
Nonsegmental Vitiligo
Location: Fountain Valley CA, Los Angeles CA, San Diego CA,
Sponsor: Takeda
Sex: All
Age: 18 - 70+
Code: NCT07108283
Phase2, Recruiting
Active & Responsive
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
for
Psoriasis, Overweight or Obesity
Location: Fountain Valley CA, Los Angeles CA, Northridge CA,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT06857942
Recruiting
Active & ResponsiveNew
Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)
for
Esophageal Carcinoma, Gastric Cancer (Diagnosis),
Location: Orange CA
Sponsor: University of California, Irvine
Sex: All
Age: 18+
Code: NCT07795749
Phase2, Recruiting
Active & Responsive
Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT
for
Ovarian Cancer, Cognitive Impairment
Location: Orange CA
Sponsor: University of California, Irvine
Sex: Female
Age: 18+
Code: NCT04520139
Phase1, Phase2, Recruiting
Active & Responsive
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
for
Colorectal Cancer
Location: Orange VA, Whittier CA, Los Angeles CA, La Jolla CA,
Sponsor: Takeda
Sex: All
Age: 18+
Code: NCT06562543
Recruiting
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Active & Responsive
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
for
NASH - Nonalcoholic Steatohepatitis,
Location: Orange CA, Fountain Valley CA, Long Beach CA,
Sponsor: Akero Therapeutics, Inc
Sex: All
Age: 18 - 70+
Code: NCT06528314
Phase3, Recruiting
Active & Responsive
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
for
NASH With Fibrosis, MASH With Fibrosis
Location: Orange CA, Long Beach CA, Inglewood CA, Los Angeles CA,
Sponsor: Akero Therapeutics, Inc
Sex: All
Age: 18 - 70+
Code: NCT06215716
Phase3, Recruiting
Active & Responsive
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Location: Lake Forest CA, Covina CA, Huntington Park CA,
Sponsor: Amgen
Sex: All
Age: 45 - 70+
Code: NCT07037433
Phase3, Recruiting
Active & Responsive
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
for
Healthy Participants
Location: Lake Forest CA, Anaheim CA, Walnut Creek CA,
Sponsor: Pfizer
Sex: All
Age: 18 - 64
Code: NCT07122986
Phase1, Recruiting
Active & Responsive
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
for
Crohn's Disease
Location: Orange CA, Anaheim CA, Los Angeles CA, Lancaster CA,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 16 - 70+
Code: NCT06430801
Phase3, Recruiting
Active & Responsive
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
for
Autosomal Dominant Polycystic Kidney Disease
Location: Orange CA, Pomona CA, Los Angeles CA,
Sponsor: Calico Life Sciences LLC
Sex: All
Age: 18 - 55
Code: NCT06902558
Phase2, Recruiting
Active & Responsive
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
for
Genetic Disease
Location: Orange CA, Stanford CA, Seattle WA, Houston TX,
Sponsor: National Human Genome Research Institute (NHGRI)
Sex: All
Age: 0 - 70+
Code: NCT02450851
Recruiting
Active & Responsive
Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)
for
Overactive Bladder (OAB)
Location: Orange CA, Beverly Hills CA, Los Angeles CA,
Sponsor: FemPulse Corporation
Sex: Female
Age: 21+
Code: NCT07195656
Recruiting
Active & Responsive
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
for
Gastric Adenocarcinoma,
Location: Orange CA, Seattle WA, Dallas TX, Westwood KS,
Sponsor: Astellas Pharma Global Development, Inc.
Sex: All
Age: 18+
Code: NCT05365581
Phase1, Recruiting
Active & Responsive
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
for
Mesial Temporal Lobe Epilepsy
Location: Orange CA, Los Angeles CA, San Diego CA, Phoenix AZ,
Sponsor: Neurona Therapeutics
Sex: All
Age: 18 - 70+
Code: NCT05135091
Phase3, Recruiting
Active & Responsive
A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)
for
Urothelial Carcinoma
Location: Orange CA, San Francisco CA, Salt Lake City UT,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT05562830
Phase1, Phase2, Recruiting
Active & Responsive
A Study of TAK-505 in Adults With Solid Tumors
for
Malignant Solid Tumors
Location: Orange CA, San Antonio TX, Dallas TX, Houston TX,
Sponsor: Takeda
Sex: All
Age: 18+
Code: NCT07436728
Phase1, Phase2, Recruiting
Active & Responsive
Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies
for
AML (Acute Myeloid Leukemia), Glioma, Cholangiocarcinoma,
Location: Orange CA, New York NY
Sponsor: Rigel Pharmaceuticals
Sex: All
Age: 18+
Code: NCT07486713
Recruiting
Active & Responsive
Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)
for
Pompe Disease
Location: Irvine CA, St Louis MO, Cincinnati OH, Atlanta GA,
Sponsor: Shionogi
Sex: All
Age: 18+
Code: NCT07123155
Phase2, Recruiting
Active & Responsive
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
for
Kidney Disease
Location: Orange CA, Los Angeles CA, Surprise AZ, Fremont CA,