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Paid Clinical Trials Irvine

Discover 3,581 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

for
Mania, Bipolar Disorder
Location: Orange CA, La Habra CA, Bellflower CA, Chino CA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT07140913

Phase3, Recruiting
Active & Responsive

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for
Major Depressive Disorder
Location: Orange CA, Pico Rivera CA, Los Angeles CA,
Sponsor: Neurocrine Biosciences

Sex: All

Age: 18+

Code: NCT06966401

Phase3, Recruiting
Active & Responsive

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

for
Alzheimer Disease
Location: Orange CA, St Louis MO, Cordova TN, Palos Hills IL,
Sponsor: Alpha Cognition, Inc

Sex: All

Age: 50+

Code: NCT07633470

Recruiting
Active & Responsive

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

for
Type 1 Diabetes Mellitus, T1D, T1DM,
Location: Newport Beach CA, San Diego CA, Walnut Creek CA,
Sponsor: COUR Pharmaceutical Development Company, Inc.

Sex: All

Age: 12 - 35

Code: NCT06783309

Phase1, Phase2, Recruiting
Active & Responsive

Pancreatic Cancer Detection Consortium

for
Pancreatic Cancer, Pancreatic Carcinoma,
Location: Newport Beach CA, Monrovia CA, Phoenix AZ,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06388967

Recruiting

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Active & Responsive

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

for
Hypertension, Hypertension, Systolic, Hypertension, Essential
Location: Newport Beach CA, Glendale CA, Scottsdale AZ,
Sponsor: Orchestra BioMed, Inc

Sex: All

Age: 18+

Code: NCT06059638

Recruiting
Active & Responsive

IKS014 in Advanced Solid Tumors That Express HER2

for
Breast Cancer, Gastric Cancer, Gastroesophageal-junction Cancer
Location: Newport Beach CA, Fort Worth TX, Nashville TN,
Sponsor: Iksuda Therapeutics Ltd.

Sex: All

Age: 18+

Code: NCT05872295

Phase1, Recruiting
Active & Responsive

Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study

for
Type 1 Diabetes
Location: Newport Beach CA, Chicago IL, Atlanta GA, Detroit MI,
Sponsor: Indiana University

Sex: All

Age: 18+

Code: NCT07676565

Recruiting
Active & Responsive

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for
Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma,
Location: Newport Beach CA, Los Angeles CA, La Jolla CA,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT05303519

Phase3, Recruiting
Active & Responsive

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

for
Ulcerative Colitis
Location: Newport Beach CA, Los Angeles CA, Sun City AZ,
Sponsor: Takeda

Sex: All

Age: 18 - 65

Code: NCT06095128

Recruiting
Active & Responsive

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

for
Extensive Stage-small Cell Lung Cancer
Location: Newport Beach CA, Phoenix AZ, Vancouver WA,
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT06362252

Phase1, Phase2, Recruiting
Active & Responsive

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

for
Metastatic Non-small Cell Lung Cancer
Location: Newport Beach CA, Fullerton CA, Goodyear AZ,
Sponsor: NovoCure GmbH

Sex: All

Age: 18+

Code: NCT06216301

Phase3, Recruiting
Active & Responsive

Blood and Cystic Fluid From Patients Undergoing Surgery for Worrisome Pancreatic Cysts

for
Pancreatic Cyst
Location: Newport Beach CA, Atlanta GA
Sponsor: Translational Genomics Research Institute

Sex: All

Age: 18+

Code: NCT07767227

Recruiting
Active & Responsive

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for
Diabetes Mellitus, Type 2, Hypertension,
Location: Orange CA, Long Beach CA, Pomona CA, Torrance CA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07064473

Phase3, Recruiting
Active & Responsive

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease

for
Graves' Disease, Graves Disease
Location: Orange CA, Pasadena CA, Shavano Park TX, Irving TX,
Sponsor: argenx

Sex: All

Age: 18+

Code: NCT07570316

Phase3, Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

for
Major Depressive Disorder (MDD)
Location: Orange CA, Garden Grove CA, Lemon Grove CA,
Sponsor: Vanda Pharmaceuticals

Sex: All

Age: 18 - 65

Code: NCT06830044

Phase3, Recruiting
Active & Responsive

A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer

for
IO-resistant sqNSCLC
Location: Fountain Valley CA, Los Alamitos CA, Torrance CA,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT07217301

Phase3, Recruiting
Active & Responsive

Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

for
Parenteral Nutrition Associated Liver Disease (PNALD),
Location: Fountain Valley CA, Los Angeles CA, Seattle WA,
Sponsor: Fresenius Kabi

Sex: All

Age: 0 - 17

Code: NCT06274788

Recruiting
Active & Responsive

A Study of IPN10200 for the Treatment of Cervical Dystonia in Adults

for
Cervical Dystonia
Location: Fountain Valley CA, Spokane WA, Chicago IL, Atlanta GA,
Sponsor: Ipsen

Sex: All

Age: 18 - 70+

Code: NCT06937931

Phase2, Recruiting
Active & Responsive

A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo

for
Non-segmental Vitiligo
Location: Fountain Valley CA, Thousand Oaks CA, San Diego CA,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 18 - 70+

Code: NCT07431177

Phase2, Recruiting