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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: Duarte CA, San Diego CA, Las Vegas NV, Phoenix AZ,
Sponsor: Immuneering Corporation

Sex: All

Age: 18+

Code: NCT07562152

Phase3, Recruiting
Active & Responsive

A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

for
AML, MDS
Location: Duarte CA, Denver CO, Aurora CO, Austin TX, Dallas TX,
Sponsor: TScan Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05473910

Phase1, Recruiting
Active & Responsive

A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes

for
Diabetes Mellitus, Type 1, Impaired Hypoglycemic Awareness,
Location: Duarte CA, San Francisco CA, Vancouver, Dallas TX,
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 18 - 65

Code: NCT04786262

Phase3, Recruiting
Active & Responsive

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

for
Prostate Carcinoma
Location: Duarte CA, San Francisco CA, Portland OR, Seattle WA,
Sponsor: University of Washington

Sex: Male

Age: 40+

Code: NCT04472338

Recruiting
Active & Responsive

Study of REM-422 in Patients With AML or Higher Risk MDS

for
Myelodysplastic Syndromes,
Location: Duarte CA, Houston TX, Tampa FL, New York NY, Boston MA
Sponsor: Remix Therapeutics

Sex: All

Age: 18+

Code: NCT06297941

Phase1, Recruiting

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Active & Responsive

A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

for
Metastatic Hepatocellular Carcinoma,
Location: Duarte CA, Goodyear AZ, Houston TX, Zion IL,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06427941

Phase1, Phase2, Recruiting
Active & Responsive

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

for
Hematologic Malignancy, GvHD, GVHD,Acute, GVHD, Chronic,
Location: Duarte CA, Seattle WA, Minneapolis MN, New York NY,
Sponsor: Tr1X, Inc.

Sex: All

Age: 18+

Code: NCT06462365

Phase1, Recruiting
Active & Responsive

Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for
Lymphoid Leukemia
Location: Duarte CA, Palo Alto CA, San Francisco CA, Tucson AZ,
Sponsor: Stanford University

Sex: All

Age: 0 - 26

Code: NCT05865301

Recruiting
Active & Responsive

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

for
Breast Atypical Hyperplasia, Breast Carcinoma,
Location: Duarte CA, Kansas City KS, Chicago IL, Columbus OH
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 35+

Code: NCT05941520

Phase2, Recruiting
Active & Responsive

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

for
Lymphoma, Non-Hodgkin, B-cell Lymphoma,
Location: Duarte CA, Denver CO, Aurora CO, Seattle WA, Dallas TX,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07101328

Phase1, Recruiting
Active & Responsive

A Study of Rebecsinib for Patients With Relapsed/Refractory Secondary Acute Myeloid Leukemia or High Risk Myelofibrosis

for
Secondary AML, Myelofibrosis
Location: Duarte CA, San Diego CA, Sacramento CA
Sponsor: Aspera Biomedicines, Inc.

Sex: All

Age: 18+

Code: NCT07250646

Phase1, Recruiting
Active & Responsive

A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

for
Multiple Myeloma in Relapse, Myeloma Multiple,
Location: Duarte CA, Palo Alto CA, San Francisco CA, Portland OR,
Sponsor: Kelonia Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07075185

Phase1, Recruiting
Active & Responsive

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

for
Colorectal Cancer, Colorectal Cancer (CRC),
Location: Duarte CA, Los Angeles CA, Phoenix AZ, San Francisco CA,
Sponsor: Cartography Biosciences

Sex: All

Age: 18+

Code: NCT07321106

Phase1, Recruiting
Active & Responsive

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for
Breast Neoplasms, Colorectal Neoplasms, Prostate Neoplasm,
Location: Duarte CA, Santa Monica CA, Stanford CA, Houston TX,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07114601

Phase1, Recruiting
Active & Responsive

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

for
Bone Pain, Metastatic Malignant Neoplasm in the Bone,
Location: Duarte CA, Los Angeles CA, Minneapolis MN, Atlanta GA,
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT03858205

Recruiting
Active & Responsive

Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for
Acute Myeloid Leukemia
Location: Duarte CA, Phoenix AZ, Stanford CA, Salt Lake City UT,
Sponsor: Norman J. Lacayo

Sex: All

Age: 0 - 21

Code: NCT05101551

Phase1, Recruiting
Active & Responsive

Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma

for
Non-Hodgkin Lymphoma, Adult, Non-Hodgkin Lymphoma, Refractory,
Location: Duarte CA, Denver CO, Aurora CO, Austin TX,
Sponsor: Marker Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT05798897

Phase1, Recruiting
Active & Responsive

Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL

for
CLL/SLL
Location: Duarte CA, Seattle WA, Cleveland OH, Canton OH,
Sponsor: Ascentage Pharma Group Inc.

Sex: All

Age: 18 - 70+

Code: NCT04215809

Phase1, Recruiting
Active & ResponsiveNew

A Modular, Phase I/II, Multicentre Study to Evaluate AZD4045, in Participants With Relapsed or Refractory Multiple Myeloma

for
Relapsed or Refractory Multiple Myeloma
Location: Duarte CA
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07681596

Phase1, Phase2, Recruiting
Active & Responsive

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Duarte CA, Atlanta GA, Boston MA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06059391

Phase2, Recruiting