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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Culturally Informed Patient Navigation Program (CFPN) to Reduce Delays Between Diagnosis and Treatment in American Indian and Alaska Native Cancer Patients Living in Rural California

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Los Angeles CA, Bishop CA
Sponsor: University of Southern California

Sex: All

Age: 0+

Code: NCT07332312

Recruiting

Geriatric Assessment and Management for Older Adults Undergoing Chemotherapy and Radiation Therapy for Head and Neck Cancer and Their Family Caregivers

for
Localized Head and Neck Carcinoma
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07225855

Recruiting

Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant

for
Acute Myeloid Leukemia, Graft Versus Host Disease,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06996119

Phase1, Recruiting

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

for
Squamous Cell Carcinoma of Head and Neck
Location: Fullerton CA, Los Angeles CA, Murrieta CA, La Jolla CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07276399

Phase3, Recruiting

A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States

for
Advanced Unresectable Gastric Adenocarcinoma,
Location: Cerritos CA, Los Angeles CA, St Louis MO, Canton OH,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07554521

Phase2, Recruiting

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A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

for
Lupus Erythematosus, Systemic
Location: Fullerton CA, La Palma CA, Torrance CA, Upland CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18 - 70+

Code: NCT07438496

Phase3, Recruiting

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

for
Recurrent Astrocytoma, IDH-Mutant, Grade 4,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07544992

Phase1, Recruiting

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

for
Diabetes Mellitus, Type 2
Location: Los Alamitos CA, Long Beach CA, Lomita CA, Lancaster CA,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18 - 70+

Code: NCT07415954

Phase2, Recruiting

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

for
Neurofibromatosis Type 2, Vestibular Schwannoma,
Location: Los Angeles CA, Baltimore MD, Miami FL, New York NY,
Sponsor: Scott R. Plotkin, MD, PhD

Sex: All

Age: 12+

Code: NCT04374305

Phase2, Recruiting

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

for
Pancreatic Neoplasm
Location: Loma Linda CA, Burbank CA, Los Angeles CA, La Jolla CA,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 50 - 70+

Code: NCT04239573

Recruiting

Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety

for
Generalized Anxiety Disorder (GAD)
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT07430800

Recruiting

Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications

for
Negative Symptoms of Schizophrenia
Location: Garden Grove CA, Bellflower CA, Riverside CA,
Sponsor: Minerva Neurosciences

Sex: All

Age: 18 - 55

Code: NCT07565428

Phase3, Recruiting

A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs

for
Prostate Cancer
Location: Duarte CA, Salt Lake City UT, Calgary, St Louis MO,
Sponsor: AstraZeneca

Sex: Male

Age: 18+

Code: NCT07336446

Phase1, Phase2, Recruiting

Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients

for
Fracture Lower Leg, Diabetes, Fracture Fixation, Internal
Location: Los Angeles CA, El Paso TX
Sponsor: Texas Tech University Health Sciences Center, El Paso

Sex: All

Age: 18+

Code: NCT07561541

Recruiting

Post-market Safety and Effectiveness of the CORUS-LX System in Improving Lumbar Interbody Fusion Outcomes

for
Radiculopathy Lumbar, Degenerative Lumbar Disc Disease
Location: Los Angeles CA, Los Gatos CA, Scottsdale AZ,
Sponsor: Providence Medical Technology, Inc.

Sex: All

Age: 18 - 70+

Code: NCT07222787

Recruiting

Applause Study I - Append System Early Feasibility Study

for
Non Valvular Atrial Fibrillation
Location: Los Angeles CA, Jonesboro AR, New York NY
Sponsor: Append Medical Ltd.

Sex: All

Age: 18+

Code: NCT07278869

Recruiting

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for
Carcinoma, Non-Small-Cell Lung
Location: Fullerton CA, Long Beach CA, Denver CO, San Antonio TX,
Sponsor: Mirati Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT06875310

Phase3, Recruiting

A Study of TORL-5-700 in Relapsed/Refractory Non Hodgkin's Lymphoma

for
Histologically Confirmed Relapsed or Refractory B-cell Non-Hodgkin Lymphoma,
Location: Fullerton CA, Santa Monica CA, Stanford CA, Dallas TX,
Sponsor: TORL Biotherapeutics, LLC

Sex: All

Age: 18+

Code: NCT07439653

Phase1, Phase2, Recruiting

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

for
KRAS Altered Advanced or Metastatic Solid Tumors
Location: Duarte CA, Los Angeles CA, San Antonio TX, Edmonton,
Sponsor: Amgen

Sex: All

Age: 18+

Code: NCT07094113

Phase1, Recruiting

Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants

for
End Stage Kidney Disease
Location: San Dimas CA, Houston TX, Seattle WA, Knoxville TN,
Sponsor: Diality Inc.

Sex: All

Age: 18 - 70+

Code: NCT06613568

Recruiting