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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

for
Diabetic Macular Edema
Location: Arcadia CA, Glendale CA, Beverly Hills CA, Oxnard CA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07553429

Phase1, Phase2, Recruiting

Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas

for
Follicular Helper T-Cell Lymphoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07293403

Phase2, Recruiting

A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

for
Multiple Myeloma
Location: Los Alamitos CA, Whittier CA, Torrance CA,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT07227311

Phase2, Recruiting

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for
Metastatic Gastric Adenocarcinoma,
Location: Los Alamitos CA, Las Vegas NV, Chandler AZ,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT07043400

Phase3, Recruiting

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

for
HER2-positive Breast Cancer, Breast Cancer
Location: Los Alamitos CA, Long Beach CA, Albuquerque NM,
Sponsor: Jazz Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07102381

Phase2, Recruiting

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A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

for
Interstitial Lung Diseases,
Location: Los Angeles CA, San Diego CA, Scottsdale AZ,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT06806592

Phase3, Recruiting

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

for
Breast Neoplasms
Location: Los Alamitos CA, Los Angeles CA, Santa Monica CA,
Sponsor: BioNTech SE

Sex: All

Age: 18+

Code: NCT07173751

Phase3, Recruiting

A Study of ZW251 in Participants With Advanced Solid Tumors

for
Hepatocellular Carcinoma,
Location: Santa Monica CA, San Francisco CA, San Antonio TX,
Sponsor: Zymeworks BC Inc.

Sex: All

Age: 18+

Code: NCT07164313

Phase1, Recruiting
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A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

for
Alopecia Areata
Location: Fountain Valley CA, Los Angeles CA, Thousand Oaks CA,
Sponsor: AbbVie

Sex: All

Age: 12 - 63

Code: NCT06012240

Phase3, Recruiting

Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

for
Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus
Location: Los Angeles CA, Santa Barbara CA, Aurora CO, Houston TX,
Sponsor: Insulet Corporation

Sex: All

Age: 14 - 70+

Code: NCT07579702

Recruiting

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

for
Colorectal Neoplasms
Location: Los Alamitos CA, Torrance CA, Los Angeles CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06750094

Phase3, Recruiting

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

for
Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation,
Location: Los Alamitos CA, Los Angeles CA, Houston TX, Chicago IL,
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 18+

Code: NCT06501625

Phase1, Phase2, Recruiting

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for
Colorectal Neoplasms
Location: Los Alamitos CA, Torrance CA, Los Angeles CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06662786

Phase3, Recruiting

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

for
Macular Edema Secondary to Inflammation
Location: Pasadena CA, Glendale CA, Redlands CA, Los Angeles CA,
Sponsor: Kodiak Sciences Inc

Sex: All

Age: 18+

Code: NCT06990399

Phase3, Recruiting

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

for
Colon Adenocarcinoma, Rectal Adenocarcinoma
Location: Los Angeles CA, Santa Monica CA, Las Vegas NV,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06997497

Phase3, Recruiting

Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

for
Severe Hypertriglyceridemia
Location: Los Angeles CA, Santa Clarita CA, Seattle WA,
Sponsor: Arrowhead Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06880770

Phase3, Recruiting

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

for
Prostate Cancer
Location: Los Angeles CA, La Jolla CA, San Diego CA,
Sponsor: AstraZeneca

Sex: Male

Age: 18+

Code: NCT06952803

Phase3, Recruiting

A Long Term Follow-up Study of TScan TCR-T Products

for
AML, ALL, MDS
Location: Duarte CA, New York NY
Sponsor: TScan Therapeutics, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06976736

Recruiting

ORION-1: Study of AVZO-023 as a Single Agent and in Combination With AVZO-021, and/or Endocrine Therapy in Advanced Solid Tumors

for
HR+/HER2- Breast Cancer, HR+, HER2-, Advanced Breast Cancer
Location: Los Angeles CA, New Haven CT, Orlando FL, Tampa FL,
Sponsor: Avenzo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06998407

Phase1, Phase2, Recruiting

AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions

for
Coronary Arterial Disease (CAD),
Location: Los Angeles CA, La Jolla CA, Thousand Oaks CA,
Sponsor: Boston Scientific Corporation

Sex: All

Age: 18+

Code: NCT06959524

Recruiting