Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE
for
Macular Edema Secondary to Inflammation
Location: Pasadena CA, Glendale CA, Redlands CA, Los Angeles CA,
Sponsor: Kodiak Sciences Inc
Sex: All
Age: 18+
Code: NCT06996080
Phase3, Recruiting
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
for
HER2-positive Gastric Cancer,
Location: Los Alamitos CA, Upland CA, Duarte CA, Los Angeles CA,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT06764875
Phase3, Recruiting
Parent Navigator Program (PNP) to Improve Outcomes in Latino/x Children and Parents
for
Congenital Heart Disease
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles
Sex: All
Age: 0+
Code: NCT07023367
Recruiting
Pacritinib in Combination With a BTK Inhibitor for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
Location: Fullerton CA, Long Beach CA, Pasadena CA,
Sponsor: Amgen
Sex: All
Age: 50+
Code: NCT07614776
Phase3, Recruiting
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A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
for
Geographic Atrophy, Macular Degeneration
Location: Fullerton CA, Pasadena CA, Poway CA, La Jolla CA,
Sponsor: Janssen Research & Development, LLC
Sex: All
Age: 60+
Code: NCT06635148
Phase2, Phase3, Recruiting
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
for
Small Cell Lung Cancer
Location: Fullerton CA, Los Angeles CA, San Francisco CA,
Sponsor: Daiichi Sankyo
Sex: All
Age: 18+
Code: NCT06203210
Phase3, Recruiting
A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia
for
Immune Thrombocytopenia (ITP)
Location: Los Angeles CA, Palo Alto CA, Austin TX,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT06721013
Phase1, Phase2, Recruiting
An Evaluation of the Pink Cloud Application in Post- Treatment Substance Use Disorder Support
for
Substance Use
Location: Los Angeles CA
Sponsor: Loyola Marymount University
Sex: All
Age: 18+
Code: NCT07042451
Recruiting
Hormonal Contraception Access Through Pharmacist Prescribing Implementation
for
Contraception, Pharmaceutical Services,
Location: Del Mar CA
Sponsor: EMPOWERX INC
Sex: All
Age: 18+
Code: NCT06823037
Recruiting
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
for
Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Location: Los Angeles CA, Phoenix AZ, Tucson AZ,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 18+
Code: NCT07063745
Phase2, Phase3, Recruiting
A Study to Assess How Effective and Safe NVD003 is for Treating Patients With Congenital Pseudarthrosis of the Tibia.
for
Congenital Pseudarthrosis of Tibia
Location: Loma Linda CA, Phoenix AZ, Rochester MN, Baltimore MD
Sponsor: Novadip Biosciences
Sex: All
Age: 0 - 17
Code: NCT07112443
Phase3, Recruiting
Alternative Splicing Based Prediction of Chemotherapy Response in Gastric Cancer
for
Gastric Cancer
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT07587229
Recruiting
Molecular Profiling for Risk Stratification in Appendiceal Cancer
for
Appendiceal Cancer, Appendiceal Adenocarcinoma
Location: Durate CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT07587268
Recruiting
GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study
for
Aortic Arch Dissection, Aortic Arch Aneurysm
Location: Los Angeles CA, Scottsdale AZ, Sacramento CA, Murray UT,
Sponsor: W.L.Gore & Associates
Sex: All
Age: 18+
Code: NCT07166133
Recruiting
Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
for
End of Life, Cancer
Location: Fullerton CA, Duarte CA, Los Angeles CA, Fresno CA,
Sponsor: Stanford University
Sex: All
Age: 18+
Code: NCT05297734
Recruiting
Study of FID-022 in Participants With Advanced Solid Tumors
for
Advanced Solid Tumors
Location: Duarte CA, Los Angeles CA, Tampa FL
Sponsor: Fulgent Pharma LLC.
Sex: All
Age: 18+
Code: NCT06694480
Phase1, Recruiting
Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
for
Glioblastoma Multiforme
Location: Los Angeles CA
Sponsor: Chirag G. Patil
Sex: All
Age: 18+
Code: NCT04977375
Phase1, Phase2, Recruiting
A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
for
CLL, Chronic Lymphocytic Leukemia
Location: Whittier CA, Los Angeles CA, San Diego CA, Eugene OR,
Sponsor: BeOne Medicines
Sex: All
Age: 18+
Code: NCT06846671
Phase3, Recruiting
A Post-market, Real-world Experience: Expanding Access to Care by Incorporating the Symani® Surgical System and Enabling Surgeons
for
Open Surgery, Lymphedema, Free Tissue Transfer, Microsurgery,
Location: Beverly Hills CA, Cleveland OH, Tampa FL, Buffalo NY,