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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Los Alamitos CA, Los Angeles CA, Irving TX, Houston TX,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT06589596

Phase1, Recruiting

Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors

for
Small Cell Lung Cancer Metastatic or Locally Advanced,
Location: Glendale CA, Long Beach CA, Los Angeles CA, Aurora CO,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT07080242

Phase1, Recruiting
New

BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

for
Small Cell Lung Cancer Extensive Stage, Small-cell Lung Cancer,
Location: Glendale CA, Long Beach CA, Los Angeles CA, Fairfax VA,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT07625644

Phase3, Recruiting

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

for
Colitis, Ulcerative
Location: Los Alamitos CA, La Jolla CA, Mesa AZ, Littleton CO,
Sponsor: Pfizer

Sex: All

Age: 18 - 64

Code: NCT06398626

Recruiting

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

for
Overweight, Obesity
Location: Los Alamitos CA, Long Beach CA, Los Angeles CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07282600

Phase3, Recruiting

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Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for
Breast Cancer, Locally Advanced Breast Cancer,
Location: Los Alamitos CA, Beverly Hills CA, La Jolla CA,
Sponsor: Olema Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT07085767

Phase3, Recruiting

Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules

for
Thyroid Gland Nodule
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 19+

Code: NCT03676647

Recruiting

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

for
Major Depressive Disorder (MDD)
Location: Costa Mesa CA, Bellflower CA, Phoenix AZ, Lafayette CA,
Sponsor: Draig Therapeutics Ltd

Sex: All

Age: 18 - 70+

Code: NCT07610473

Phase2, Recruiting

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

for
COVID-19 SARS-CoV-2 Infection
Location: Los Alamitos CA, Long Beach CA, South Gate CA,
Sponsor: Pfizer

Sex: All

Age: 12+

Code: NCT06679140

Phase3, Recruiting
New

AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications

for
Type 2 Diabetes, Cardiovascular Risk
Location: Los Alamitos CA, San Dimas CA, Lomita CA, Northridge CA,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 45+

Code: NCT07797335

Phase3, Recruiting

PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis

for
Lupus Nephritis
Location: Los Alamitos CA, La Mesa CA, Las Vegas NV, El Paso TX,
Sponsor: Aurinia Pharmaceuticals Inc.

Sex: All

Age: 18 - 70+

Code: NCT07611214

Recruiting

Transcatheter vs. Surgical Treatment of Degenerative Mitral Regurgitation

for
Degenerative Mitral Valve Disease
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 60+

Code: NCT07605715

Recruiting

Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts

for
Cerebral Vasospasm, Aneurysmal Subarachnoid Hemorrhage (aSAH)
Location: Burbank CA, Walnut Creek CA, Salt Lake City UT,
Sponsor: Vesalio

Sex: All

Age: 22+

Code: NCT06893588

Recruiting

Menopausal HT for Women Living With HIV (HoT)

for
HIV Infection, Menopause
Location: Torrance CA, Los Angeles CA, San Diego CA,
Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Sex: Female

Age: 40 - 60

Code: NCT06856174

Recruiting

Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration

for
Neovascular (Wet) Age-Related Macular Degeneration
Location: Beverly Hills CA, McAllen TX, The Woodlands TX,
Sponsor: Eyconis INC.

Sex: All

Age: 50+

Code: NCT07587515

Phase1, Phase2, Recruiting

Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease

for
Peripheral Artery Disease (PAD)
Location: Los Angeles CA, Oxnard CA, Avondale AZ, Amarillo TX,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07318610

Phase3, Recruiting

An Open-label Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

for
Phelan-McDermid Syndrome
Location: Glendale CA, San Rafael CA, Houston TX, Birmingham AL,
Sponsor: Neuren Pharmaceuticals Limited

Sex: All

Age: 3 - 12

Code: NCT07593391

Phase3, Recruiting

Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer

for
Prostate Adenocarcinoma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: Male

Age: 40+

Code: NCT07468903

Recruiting

A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

for
Untreated Follicular Lymphoma
Location: Los Alamitos CA, Springfield MO, Winnipeg,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06549595

Phase3, Recruiting

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

for
Cervical Squamous Cell Carcinoma,
Location: Los Angeles CA, Phoenix AZ, San Antonio TX, Houston TX,
Sponsor: Alentis Therapeutics AG

Sex: All

Age: 18+

Code: NCT07169734

Phase1, Phase2, Recruiting