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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Encinitas CA, La Jolla CA, San Diego CA, Surprise AZ,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06532279

Phase2, Recruiting

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for
Recurrent Mycosis Fungoides, Recurrent Sezary Syndrome,
Location: Duarte CA, St Louis MO
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07003100

Recruiting

Transcatheter Fontan Stenting: Impact on Hepatic Stiffness and Exercise Capacity

for
Single-ventricle, Stenosis
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles

Sex: All

Age: 12 - 21

Code: NCT07073612

Recruiting

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

for
Agitation Associated With Alzheimer's Dementia
Location: Anaheim CA, Las Vegas NV, Tampa FL, Brandon FL,
Sponsor: Intra-Cellular Therapies, Inc.

Sex: All

Age: 55+

Code: NCT06651567

Phase2, Recruiting

Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Upland CA, Duarte CA, Torrance CA, Arcadia CA,
Sponsor: City of Hope Medical Center

Sex: Female

Age: 40+

Code: NCT06954831

Phase2, Recruiting

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Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

for
High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements,
Location: Los Angeles CA, Portland OR, Missoula MT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06649812

Phase2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for
Colorectal Cancer
Location: Fullerton CA, Los Angeles CA, Portland OR,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07023289

Phase2, Recruiting

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

for
Asthma
Location: Huntington Beach CA, Laguna Niguel CA, La Palma CA,
Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All

Age: 12+

Code: NCT06664619

Phase3, Recruiting

A Phase 2 Study of PTX 100 in Patients With Relapsed/Refractory CTCL

for
CTCL
Location: Duarte CA, Rochester NY, Richmond VA, New Haven CT,
Sponsor: Prescient Therapeutics, Ltd.

Sex: All

Age: 18+

Code: NCT06854653

Phase2, Recruiting
Featured

A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for
Non-Squamous Non-Small Cell Lung Cancer
Location: Newport Beach CA, Los Angeles CA, Chandler AZ, Reno NV,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07005102

Phase2, Phase3, Recruiting

ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial

for
Glioblastoma, Glioblastoma, IDH-Wildtype, Gliosarcoma,
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07089641

Phase1, Recruiting

Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease

for
Graves Disease
Location: Huntington Beach CA, Burbank CA, San Diego CA,
Sponsor: Biohaven Therapeutics Ltd.

Sex: All

Age: 18 - 70

Code: NCT07661056

Phase3, Recruiting

HEPA, PM2.5, and Cardiometabolic Health

for
Air Pollution, Cardiometabolic Health
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 65 - 70+

Code: NCT05718245

Recruiting

A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

for
Asthma
Location: Mission Viejo CA, Huntington Beach CA, Bakersfield CA,
Sponsor: GlaxoSmithKline

Sex: All

Age: 12 - 17

Code: NCT05757102

Phase3, Recruiting

A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)

for
Dry Age-related Macular Degeneration, Geographic Atrophy
Location: Huntington Beach CA, Los Angeles CA, Austin TX,
Sponsor: Regenerative Patch Technologies, LLC

Sex: All

Age: 55 - 70+

Code: NCT06557460

Phase2, Recruiting

A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC)

for
Neoplasms, Lung
Location: Los Angeles CA, Toronto, Wilson NC, Ottawa, Montreal
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT07099898

Phase3, Recruiting

Effects of Using a Storybook, to Explain Leukemia to Children Versus the Standard Child Life Intervention, on Parental Stress.

for
Leukemia
Location: Los Angeles CA
Sponsor: Children's Hospital Los Angeles

Sex: All

Age: 3+

Code: NCT06360718

Recruiting

A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema

for
Macular Edema
Location: Huntington Beach CA, Arcadia CA, Pasadena CA, Poway CA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT06962839

Phase2, Recruiting

Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for
Proliferative Diabetic Retinopathy (PDR)
Location: Huntington Beach CA, Loma Linda CA, Santa Barbara CA,
Sponsor: Jaeb Center for Health Research

Sex: All

Age: 18+

Code: NCT06790784

Phase3, Recruiting

Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for
Epiretinal Membrane
Location: Huntington Beach CA, Torrance CA, Glendale CA,
Sponsor: Jaeb Center for Health Research

Sex: All

Age: 50+

Code: NCT05145491

Recruiting