Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
for
Tophaceous Gout
Location: Orange CA, Norco CA, Covina CA, Menifee CA,
Sponsor: Crystalys Therapeutics
Sex: All
Age: 18 - 70+
Code: NCT07089888
Phase3, Recruiting
A Study of Lorigerlimab in Participants With Advanced Solid Tumors
for
Platinum-resistant Ovarian Cancer,
Location: Los Angeles CA, San Antonio TX, Houston TX,
Sponsor: MacroGenics
Sex: Female
Age: 18+
Code: NCT06730347
Phase2, Recruiting
Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers
for
Head and Neck Carcinoma
Location: Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT06985784
Recruiting
This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma
for
Non-Hodgkin Lymphoma Refractory/ Relapsed,
Location: Duarte CA, Seattle WA, St Louis MO, Nashville TN,
Sponsor: LTZ Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT07121946
Phase1, Recruiting
Improving Mobility After Revascularization in Peripheral Artery Disease
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Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
for
Atrial Fibrillation (AF)
Location: Huntington Beach CA, Covina CA, Pomona CA, Pasadena CA,
Sponsor: Regeneron Pharmaceuticals
Sex: All
Age: 18+
Code: NCT07175428
Phase2, Recruiting
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
for
Major Depressive Disorder (MDD),
Location: Garden Grove CA, Redlands CA, San Jose CA, Glendale CA,
Sponsor: Seaport Therapeutics
Sex: All
Age: 18 - 65
Code: NCT07065240
Phase2, Recruiting
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™
for
Aortic Regurgitation, Aortic Valve Insufficiency,
Location: Los Angeles CA, La Jolla CA, Thousand Oaks CA,
Sponsor: JenaValve Technology, Inc.
Sex: All
Age: 0+
Code: NCT06608823
Recruiting
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
for
Atrial Fibrillation (AF)
Location: Huntington Beach CA, Pasadena CA, West Hills CA,
Sponsor: Regeneron Pharmaceuticals
Sex: All
Age: 18+
Code: NCT07430956
Phase3, Recruiting
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
for
Diabetic Kidney Disease (DKD)
Location: Huntington Beach CA, San Dimas CA, Victorville CA,
Sponsor: Regeneron Pharmaceuticals
Sex: All
Age: 18 - 70+
Code: NCT07271186
Phase2, Recruiting
A Platform Study of Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer
for
High-risk Prostate Cancer
Location: Los Angeles CA
Sponsor: Edwin Posadas, MD
Sex: Male
Age: 18+
Code: NCT06888102
Early_phase1, Recruiting
Efficacy, Safety, and Tolerability of NBI-1065890 Versus Placebo in Adults With Tardive Dyskinesia
for
Tardive Dyskinesia
Location: Huntington Beach CA, Long Beach CA, Chino CA,
Sponsor: Neurocrine Biosciences
Sex: All
Age: 18 - 70+
Code: NCT07365462
Phase2, Recruiting
Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple Myeloma
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia
for
Healthy Participants, Dyslipidemia
Location: Glendale CA, San Antonio TX, Inverness FL,
Sponsor: AstraZeneca
Sex: All
Age: 18 - 70
Code: NCT06980428
Phase1, Recruiting
A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)
for
Multiple Myeloma
Location: Duarte CA, Denver CO, Houston TX, Iowa City IA,
Sponsor: AstraZeneca
Sex: All
Age: 18+
Code: NCT07073547
Phase1, Recruiting
A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema
for
Atopic Dermatitis, Eczema, Atopic
Location: Huntington Beach CA, Northridge CA, Pittsburgh PA,
Sponsor: Pfizer
Sex: All
Age: 18 - 64
Code: NCT07216027
Phase2, Recruiting
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis