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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

for
Anaplastic Large Cell Lymphoma, ALK-Negative,
Location: Irvine CA, Orange CA, Duarte CA, Burbank CA, Phoenix AZ,
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18 - 70+

Code: NCT06724237

Phase3, Recruiting

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

for
B Acute Lymphoblastic Leukemia
Location: Irvine CA, Costa Mesa CA, Orange CA, Las Vegas NV,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18 - 39

Code: NCT03150693

Phase3, Recruiting

Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

for
Sinonasal Squamous Cell Carcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Sacramento CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07281417

Phase2, Recruiting

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative,
Location: Irvine CA, Orange CA, Duarte CA, La Jolla CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT03739814

Phase2, Recruiting

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

for
Gastric Adenocarcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Palo Alto CA,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 18+

Code: NCT07001748

Phase2, Phase3, Recruiting

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Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene

for
Burkitt Lymphoma, Double-Expressor Lymphoma,
Location: Irvine CA, Orange CA, Oklahoma City OK,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07069699

Phase1, Phase2, Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Irvine CA, Orange CA, La Jolla CA, Sacramento CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07097142

Phase3, Recruiting

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

for
Advanced Hepatocellular Carcinoma,
Location: Irvine CA, Orange CA, Sunnyvale CA, Mountain View CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07166406

Phase3, Recruiting

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

for
Head and Neck Squamous Cell Carcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Portland OR,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06980038

Phase2, Recruiting

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

for
Locally Advanced Urothelial Carcinoma,
Location: Irvine CA, Orange CA, Phoenix AZ, Anaconda MT,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06524544

Phase3, Recruiting

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

for
Metastatic Colorectal Adenocarcinoma,
Location: Irvine CA, Costa Mesa CA, Orange CA, Los Angeles CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06102902

Phase1, Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

for
Non-Small Cell Lung Cancer
Location: Irvine CA, Orange CA, Reno NV, Edwards CO, Portland OR,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07100080

Phase2, Phase3, Recruiting

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for
Anatomic Stage I Breast Cancer AJCC v8,
Location: Irvine CA, Orange CA, Yorba Linda CA, La Jolla CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT06876714

Phase3, Recruiting

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for
Locally Advanced Cervical Adenocarcinoma,
Location: Irvine CA, Orange CA, Corona CA, Bellflower CA,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT07061977

Phase3, Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for
Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma
Location: Irvine CA, Orange CA, Los Angeles CA, Santa Monica CA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT06989437

Phase2, Phase3, Recruiting

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for
Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma,
Location: Irvine CA, Orange CA, La Jolla CA, Santa Barbara CA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT06958328

Phase3, Recruiting

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

for
Carcinoma, Hepatocellular, Hepatocellular Cancer,
Location: Irvine CA, Orange CA, Los Angeles CA, Pasadena CA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07227012

Phase1, Phase2, Recruiting

E-Mindfulness Approaches for Living After Breast Cancer

for
Breast Cancer, Depression
Location: Irvine CA, Costa Mesa CA, Orange CA, Anaheim CA,
Sponsor: NRG Oncology

Sex: All

Age: 18 - 50

Code: NCT06748222

Phase3, Recruiting

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

for
Prostate Cancer (Adenocarcinoma)
Location: Irvine CA, Newport Beach CA, Orange CA, Anaheim CA,
Sponsor: Canadian Cancer Trials Group

Sex: Male

Age: 18+

Code: NCT06592924

Phase3, Recruiting

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for
Recurrent Non-Muscle Invasive Bladder Carcinoma,
Location: Irvine CA, Orange CA, Phoenix AZ, Gilbert AZ,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07000084

Phase3, Recruiting