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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

for
Metastatic Microsatellite Stable Colorectal Carcinoma,
Location: Irvine CA, Orange CA, Cincinnati OH, West Chester OH,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06654037

Phase1, Recruiting

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for
Myelodysplastic Syndrome
Location: Irvine CA, Orange CA, Salt Lake City UT, Albuquerque NM,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06577441

Phase2, Recruiting

Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors

for
Metastatic Pancreatic Neuroendocrine Tumor, Pancreatic Neoplasm,
Location: Irvine CA, Orange CA, City of Saint Peters MO,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05687123

Phase1, Recruiting

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for
AL Amyloidosis
Location: Irvine CA, Orange CA, Duarte CA, Goodyear AZ, Tucson AZ,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06022939

Phase3, Recruiting

Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

for
Recurrent Ovarian High Grade Serous Adenocarcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Oklahoma City OK,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT04633239

Phase1, Recruiting

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Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

for
Metastatic Colorectal Carcinoma,
Location: Irvine CA, Orange CA, Oklahoma City OK, Fairway KS,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05803382

Phase1, Recruiting

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

for
Advanced Malignant Solid Neoplasm,
Location: Irvine CA, Orange CA, Oklahoma City OK,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05691491

Phase1, Phase2, Recruiting

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for
Carcinoma, Non-Small-Cell Lung,
Location: Irvine CA, Orange CA, Sacramento CA,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05208762

Phase1, Recruiting

Study With [225Ac]Ac-FL-020 in mCRPC Participants

for
Metastatic Castration-resistant Prostate Cancer
Location: Irvine CA, Duarte CA, Stanford CA, Cleveland OH,
Sponsor: Full-Life Technologies GmbH

Sex: Male

Age: 18+

Code: NCT06492122

Phase1, Recruiting

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

for
Non-Muscle Invasive Bladder Urothelial Carcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Bakersfield CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06770582

Phase2, Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

for
Carcinoma, Transitional Cell, Urinary Bladder Neoplasms,
Location: Irvine CA, Orange CA, Torrance CA, Los Angeles CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07218380

Phase3, Recruiting

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

for
Accelerated Phase Myeloproliferative Neoplasm,
Location: Irvine CA, Orange CA, Palo Alto CA, Sacramento CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06661915

Phase2, Recruiting

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for
Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma,
Location: Irvine CA, Orange CA, Riverside CA, Los Angeles CA,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT05256225

Phase3, Recruiting

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

for
Metastatic Malignant Solid Neoplasm,
Location: Irvine CA, Orange CA, Upland CA, Duarte CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05372614

Phase1, Recruiting

Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma

for
Recurrent Plasmablastic Lymphoma,
Location: Irvine CA, Orange CA, Duarte CA, Los Angeles CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07332507

Phase1, Recruiting

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

for
Astrocytoma, IDH-Mutant, Grade 2,
Location: Irvine CA, Orange CA, Duarte CA, La Jolla CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06860594

Phase1, Recruiting

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for
Astrocytoma, IDH-Mutant, Grade 3
Location: Irvine CA, Orange CA, Duarte CA, Bakersfield CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 12+

Code: NCT07215910

Phase3, Recruiting

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

for
Metastatic Castration-Resistant Prostate Carcinoma,
Location: Irvine CA, Orange CA, Los Angeles CA, Bakersfield CA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male

Age: 18+

Code: NCT07200830

Phase3, Recruiting

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Irvine CA, Orange CA, Beverly Hills CA, Los Angeles CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07518186

Phase3, Recruiting

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Irvine CA, Orange CA, Yorba Linda CA, Beverly Hills CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07391774

Phase3, Recruiting