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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO

for
Neovascular Age-Related Macular Degeneration (NVAMD),
Location: Santa Ana CA, Glendale CA, Modesto CA, Scottsdale AZ,
Sponsor: EyeBiotech Ltd.

Sex: All

Age: 18+

Code: NCT07205887

Phase2, Recruiting

A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

for
Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
Location: Santa Ana CA, Henderson NV, El Paso TX, Austin TX,
Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All

Age: 18 - 65

Code: NCT07096674

Phase2, Recruiting

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

for
Myopia, Juvenile Myopia, Myopia Progression
Location: Santa Ana CA, San Diego CA, Oakland CA,
Sponsor: SightGlass Vision, Inc.

Sex: All

Age: 6 - 8

Code: NCT06034327

Recruiting

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

for
Narcolepsy Type 1
Location: Santa Ana CA, Redwood City CA, Colorado Springs CO,
Sponsor: Takeda

Sex: All

Age: 16 - 70

Code: NCT05816382

Phase2, Phase3, Recruiting

Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

for
Grade 3b Follicular Lymphoma, High Grade B-Cell Lymphoma,
Location: Newport Beach CA, Huntington Beach CA, Long Beach CA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT05890352

Phase2, Recruiting

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Leflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma

for
Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Location: Newport Beach CA, Huntington Beach CA, Long Beach CA,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT04508790

Phase2, Recruiting

Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

for
Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8,
Location: Newport Beach CA, Irvine CA, Huntington Beach CA,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07288034

Phase2, Recruiting

Minimal Residual Disease Testing for the Early Detection of Cancer Recurrence in Resectable Stage II-IV Colorectal Cancer Patients

for
Resectable Colorectal Carcinoma,
Location: Newport Beach CA, Irvine CA, Huntington Beach CA,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07125729

Recruiting

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

for
Cardiotoxicity, HER2/Neu Positive,
Location: Newport Beach CA, Upland CA, Duarte CA, Torrance CA,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT03418961

Phase3, Recruiting

Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

for
Non-Arteritic Anterior Ischemic Optic Neuropathy
Location: Newport Beach CA, Los Angeles CA, Aurora CO, Houston TX,
Sponsor: Dompé Farmaceutici S.p.A

Sex: All

Age: 50 - 70+

Code: NCT07453888

Phase3, Recruiting

Tactile Pre-Visit Imagery

for
Dental Anxiety in Children, Behavior Change
Location: Santa Ana CA, Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 4 - 10

Code: NCT07719205

Recruiting

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

for
Areata Alopecia, Alopecia, Hypotrichosis, Hair Diseases,
Location: Santa Ana CA, Los Angeles CA, San Diego CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 6 - 17

Code: NCT05723198

Phase3, Recruiting

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

for
Advanced Clear Cell Renal Cell Carcinoma,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07128680

Phase1, Recruiting

First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors

for
Solid Tumor, Adult
Location: Newport Beach CA, Los Angeles CA, West Valley City UT,
Sponsor: DualityBio Inc.

Sex: All

Age: 18+

Code: NCT06554795

Phase1, Phase2, Recruiting
New

Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer

for
Colon Polyp, Colorectal Carcinoma, Localized Prostate Carcinoma,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: Male

Age: 40 - 70+

Code: NCT07790718

Recruiting

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

for
Hormone Receptor Positive HER-2 Negative Breast Cancer,
Location: Irvine CA, Fountain Valley CA, Los Angeles CA,
Sponsor: Puma Biotechnology, Inc.

Sex: All

Age: 18+

Code: NCT06369285

Phase2, Recruiting

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

for
Non-Small Cell Lung Cancer, NSCLC,
Location: Irvine CA, Duarte CA, San Diego CA, Gilbert AZ,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT06162221

Phase1, Phase2, Recruiting

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

for
Relapsed or Refractory Multiple Myeloma,
Location: Irvine CA, Duarte CA, San Francisco CA, Denver CO,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05652335

Phase1, Recruiting

Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

for
Prostate Cancer
Location: Irvine CA, Duarte CA, St Louis MO
Sponsor: Varian, a Siemens Healthineers Company

Sex: Male

Age: 18+

Code: NCT05804318

Recruiting

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

for
Breast Cancer
Location: Irvine CA, Newport Beach CA, Orange CA, Los Alamitos CA,
Sponsor: Stemline Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06492616

Phase3, Recruiting