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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for
Brain Metastases
Location: Irvine CA, Corona CA, Upland CA, Duarte CA, Torrance CA,
Sponsor: Canadian Cancer Trials Group

Sex: All

Age: 18+

Code: NCT03550391

Phase3, Recruiting

Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

for
Acute Respiratory Distress Syndrome, ARDS
Location: Irvine CA, Phoenix AZ, Davis CA, Sacramento CA,
Sponsor: Direct Biologics, LLC

Sex: All

Age: 18 - 70+

Code: NCT05354141

Phase3, Recruiting

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

for
Pediatric Migraine
Location: Costa Mesa CA, Fountain Valley CA, Anaheim CA,
Sponsor: Pfizer

Sex: All

Age: 6 - 17

Code: NCT04649242

Phase3, Recruiting

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

for
Osteoarthritis, Overweight or Obesity
Location: Santa Ana CA, Fountain Valley CA, Spring Valley CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07353931

Phase3, Recruiting

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

for
Ovarian Cancer, Lung Adenocarcinoma, Endometrial Cancer,
Location: Irvine CA, Duarte CA, Aurora CO, Portland OR,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT05797168

Phase1, Phase2, Recruiting

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for
Non-small Cell Lung Cancer (NSCLC)
Location: Irvine CA, Duarte CA, Loma Linda CA, Los Angeles CA,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT07291037

Phase3, Recruiting

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Atlanta GA, Ann Arbor MI,
Sponsor: AstraZeneca

Sex: All

Age: 18+

Code: NCT06106945

Phase1, Phase2, Recruiting

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for
Endometrial Cancer
Location: Irvine CA, Duarte CA, La Jolla CA, Eugene OR,
Sponsor: AstraZeneca

Sex: Female

Age: 18+

Code: NCT06989112

Phase3, Recruiting

The iLet Experience Study

for
Type 1 Diabetes
Location: Irvine CA
Sponsor: Beta Bionics, Inc.

Sex: All

Age: 6+

Code: NCT06891898

Recruiting

GEMINI-NSCLC: NSCLC Biomarker Study

for
Non-Small Cell Lung Cancer
Location: Fountain Valley CA, Los Angeles CA, Las Vegas NV,
Sponsor: Tempus AI

Sex: All

Age: 18+

Code: NCT05236114

Recruiting

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

for
Chronic Idiopathic Constipation (CIC)
Location: Santa Ana CA, Inglewood CA, Canoga Park CA,
Sponsor: Ardelyx

Sex: All

Age: 18 - 70+

Code: NCT07382167

Phase3, Recruiting

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for
Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung
Location: Fountain Valley CA, Beverly Hills CA, Dallas TX,
Sponsor: Lantern Pharma Inc.

Sex: All

Age: 18+

Code: NCT05456256

Phase2, Recruiting

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Location: Fountain Valley CA, Whittier CA, Los Angeles CA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06129864

Phase3, Recruiting

Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer

for
Non-small Cell Lung Cancer (NSCLC)
Location: Fountain Valley CA, San Diego CA, Santa Rosa CA,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT07288177

Phase2, Recruiting

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

for
Metastatic Castration-Resistant Prostate Cancer
Location: Fountain Valley CA, Laguna Hills CA, Anaheim CA,
Sponsor: Pfizer

Sex: Male

Age: 18+

Code: NCT06629779

Phase3, Recruiting

DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for
Relapsed Diffuse Large B-cell Lymphoma,
Location: Fountain Valley CA, Santa Fe NM, Omaha NE, Saskatoon,
Sponsor: ImmunoVaccine Technologies, Inc. (IMV Inc.)

Sex: All

Age: 18+

Code: NCT04920617

Phase2, Recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for
Metastatic Non-small Cell Lung Cancer
Location: Fountain Valley CA, La Jolla CA, San Diego CA,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06417814

Phase3, Recruiting

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

for
Type 2 Diabetes, Cortisol Excess
Location: Fountain Valley CA, Long Beach CA, Huntington Park CA,
Sponsor: Sparrow Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07296484

Phase2, Recruiting

A Safety and Immunogenicity Study of CHIKV VLP Vaccine in Children.

for
Chikungunya Virus
Location: Fountain Valley CA, West Jordan UT, Omaha NE,
Sponsor: Bavarian Nordic

Sex: All

Age: 1 - 11

Code: NCT07003984

Phase3, Recruiting

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

for
Colorectal Neoplasms
Location: Fountain Valley CA, Anaheim CA, Pasadena CA,
Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All

Age: 18+

Code: NCT05253651

Phase3, Recruiting