Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Clinical trials in Irvine address a diverse range of conditions, from mental health disorders and neurological diseases to skin conditions and cardiovascular issues. As one of California’s thriving research hubs, the city provides participants with a chance to explore cutting-edge therapies and receive specialized care, all while contributing to the advancement of medical science in their region.
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Results: 3,580
Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer
for
Non-small Cell Lung Cancer
Location: Irvine CA, Duarte CA, Phoenix AZ, Grand Junction CO,
Sponsor: Canadian Cancer Trials Group
Sex: All
Age: 18+
Code: NCT06686771
Phase3, Recruiting
Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial
for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Irvine CA, Long Beach CA, Duarte CA, Newnan GA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT07218510
Phase2, Recruiting
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
for
Breast Neoplasms, Neoplasm Metastasis
Location: Irvine CA, Duarte CA, Oceanside CA, Chandler AZ,
Sponsor: Eli Lilly and Company
Sex: All
Age: 18+
Code: NCT07174336
Phase3, Recruiting
Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia
for
Recurrent Chronic Lymphocytic Leukemia,
Location: Irvine CA, Duarte CA, Sacramento CA, Salt Lake City UT,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT07061951
Phase2, Recruiting
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
for
Advanced/Metastatic Solid Tumors, Bladder Cancer,
Location: Irvine CA, Duarte CA, San Antonio TX, Conroe TX,
Sponsor: Pfizer
Sex: All
Age: 18+
Code: NCT07090499
Phase1, Recruiting
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Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3
for
Advanced Colon Adenocarcinoma,
Location: Irvine CA, Huntington Beach CA, Corona CA,
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT07595874
Phase2, Recruiting
Different Types of Massage Therapy to Reduce Anxiety During Chemotherapy Infusion in Patients With Cancer
for
Hematopoietic and Lymphatic System Neoplasm,
Location: Irvine CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT07184294
Recruiting
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Irvine CA, Corona CA, Upland CA, Duarte CA,
Sponsor: National Cancer Institute (NCI)
Sex: All
Age: 18+
Code: NCT07061964
Phase2, Recruiting
Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer
for
Small Cell Lung Cancer, Small Cell Lung Cancer ( SCLC ),
Location: Irvine CA, Duarte CA, New Lenox IL, Hinsdale IL
Sponsor: Pfizer
Sex: All
Age: 18+
Code: NCT07476287
Phase2, Recruiting
Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors
for
Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT06731894
Phase2, Recruiting
Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer
for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT06910761
Phase2, Recruiting
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
for
Relapsed/Refractory Multiple Myeloma
Location: Irvine CA, Duarte CA, Salt Lake City UT, Seattle WA,
Sponsor: BeOne Medicines
Sex: All
Age: 18+
Code: NCT04973605
Phase1, Phase2, Recruiting
A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Irvine CA, Duarte CA, Henderson NV, Chandler AZ,
Sponsor: Loxo Oncology, Inc.
Sex: All
Age: 18+
Code: NCT06588478
Phase2, Recruiting
Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer
for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center
Sex: All
Age: 18+
Code: NCT06260033
Phase2, Recruiting
A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)
Location: Irvine CA, Stanford CA, Sacramento CA, Seattle WA,
Sponsor: Nuvalent Inc.
Sex: All
Age: 18+
Code: NCT06521554
Phase1, Recruiting
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
for
Advanced Solid Tumors, Colorectal Cancer
Location: Irvine CA, Duarte CA, Los Angeles CA,
Sponsor: Vividion Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT06004245
Phase1, Recruiting
A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer
for
Gastric Adenocarcinoma, Gastric Cancer,
Location: Irvine CA, Duarte CA, Santa Monica CA, Fort Worth TX,
Sponsor: Toray Industries, Inc
Sex: All
Age: 18+
Code: NCT06038578
Phase2, Recruiting
An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and Olaparib
for
Ovary Cancer, Peritoneal Cancer, Fallopian Tube Cancer
Location: Irvine CA, Aurora CO, Madison WI, Chicago IL,
Sponsor: University of Colorado, Denver
Sex: Female
Age: 18 - 70+
Code: NCT05887609
Phase2, Recruiting
Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
for
Prostate Adenocarcinoma, Stage IIIB Prostate Cancer AJCC v8,
Location: Irvine CA, Duarte CA, Burbank CA, Santa Maria CA,
Sponsor: SWOG Cancer Research Network
Sex: Male
Age: 18+
Code: NCT05806515
Phase2, Recruiting
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
for
Cervical Cancer
Location: Irvine CA, Newport Beach CA, Upland CA, Duarte CA,