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Paid Clinical Trials Irvine

Discover 3,580 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

for
Anatomic Stage IV Breast Cancer AJCC v8,
Location: Irvine CA, Long Beach CA, Duarte CA, South Pasadena CA,
Sponsor: City of Hope Medical Center

Sex: All

Age: 70+

Code: NCT04305834

Phase2, Recruiting

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for
Advanced Malignant Solid Neoplasm,
Location: Irvine CA, Duarte CA, Encinitas CA, La Jolla CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06311214

Phase2, Recruiting

Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

for
Lung Carcinoma
Location: Irvine CA, Upland CA, Duarte CA, Stanford CA, Davis CA,
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06196008

Recruiting

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for
Breast Cancer
Location: Irvine CA, Fullerton CA, Whittier CA, Duarte CA,
Sponsor: Greenwich LifeSciences, Inc.

Sex: All

Age: 18 - 70+

Code: NCT05232916

Phase3, Recruiting

ADG126 in Combination With Pembrolizumab in Patients With Advanced/Metastatic Solid Tumors

for
Advanced/Metastatic Solid Tumors
Location: Irvine CA, Duarte CA, Scottsdale AZ, Seattle WA,
Sponsor: Adagene Inc

Sex: All

Age: 18+

Code: NCT05405595

Phase1, Phase2, Recruiting

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Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

for
Lung Non-Small Cell Carcinoma, Malignant Solid Neoplasm,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05830058

Phase2, Recruiting

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

for
Ovarian Cancer, Fallopian Tube Cancer,
Location: Irvine CA, Orange CA, Duarte CA, Seattle WA, Chicago IL,
Sponsor: Regeneron Pharmaceuticals

Sex: Female

Age: 18+

Code: NCT04590326

Phase1, Phase2, Recruiting

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

for
Advanced Malignant Solid Neoplasm,
Location: Irvine CA, Duarte CA, La Jolla CA, San Diego CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05327010

Phase2, Recruiting

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for
Multiple Myeloma
Location: Irvine CA, Los Alamitos CA, Duarte CA, Los Angeles CA,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05552222

Phase3, Recruiting

Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer

for
Advanced Lung Non-Small Cell Carcinoma,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06249282

Phase1, Recruiting

Study of XB010 in Subjects With Solid Tumors

for
Locally Advanced or Metastatic Solid Tumors,
Location: Irvine CA, Los Angeles CA, Oklahoma City OK, Austin TX,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT06545331

Phase1, Recruiting

Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07126301

Recruiting

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

for
Nausea, Vomiting,
Location: Irvine CA, Los Alamitos CA, Walnut Creek CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07169851

Phase2, Recruiting

Adding a Live Biotherapeutic Product (CBM588) to Pembrolizumab for the Treatment of Renal Cell Cancer After Surgery

for
Clear Cell Renal Cell Carcinoma,
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07037004

Phase2, Recruiting

Study of GB-4362 With Enfortumab Vedotin and Pembrolizumab for Advanced Urothelial Cancer

for
Advanced Urothelial Cancer, Metastatic Urothelial Carcinoma
Location: Irvine CA, Duarte CA, Houston TX, Zion IL, Tucker GA,
Sponsor: Generate Biomedicines

Sex: All

Age: 18+

Code: NCT07484022

Phase1, Recruiting

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

for
Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer,
Location: Irvine CA, Goodyear AZ, Temple TX, Houston TX,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT07154290

Phase2, Recruiting

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

for
Lymphoplasmacytic Lymphoma, Waldenstrom Macroglobulinemia
Location: Irvine CA, Tucson AZ, Nampa ID, Meridian ID, Boise ID,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04840602

Phase2, Recruiting

AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

for
Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR),
Location: Irvine CA, Newport Beach CA, Irving TX, Zion IL,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07403721

Phase1, Recruiting

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Los Angeles CA, Phoenix AZ,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT07258511

Phase3, Recruiting

A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

for
Multiple Myeloma
Location: Irvine CA, Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT07225738

Recruiting