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Paid Clinical Trials Orange County

Discover 3,614 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Global Patient Registry to Monitor Long-term Safety and Effectiveness of Increlex® in Children and Adolescents With Severe Primary Insulin-like Growth Factor-1 Deficiency (SPIGFD).

for
IGF1 Deficiency
Location: Orange CA, Cincinnati OH, Miami FL
Sponsor: Esteve Pharmaceuticals, S.A.

Sex: All

Age: 2 - 18

Code: NCT00903110

Recruiting
Active & Responsive

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

for
Epileptic Encephalopathy
Location: Orange CA, Columbus OH, Boston MA
Sponsor: Institut de Recherches Internationales Servier

Sex: All

Age: 2 - 12

Code: NCT07227857

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

for
Pediatric Tumor of CNS, Pediatric Tumor of Brain,
Location: Orange CA
Sponsor: Neonc Technologies, Inc.

Sex: All

Age: 5 - 18

Code: NCT06357377

Phase 1, Recruiting
Active & Responsive

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for
Lymphoblastic Leukemia
Location: Orange CA, Los Angeles CA, Madera CA, Phoenix AZ,
Sponsor: Tanja Andrea Gruber

Sex: All

Age: 0 - 1

Code: NCT05848687

Phase 1, Phase 2, Recruiting
Active & Responsive

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

for
Sickle Cell Disease
Location: Orange CA, Houston TX, Flowood MS, Chicago IL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 12 - 70+

Code: NCT06439082

Phase 3, Recruiting

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Active & Responsive

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for
Glioblastoma
Location: Orange CA, La Jolla CA, San Francisco CA,
Sponsor: Global Coalition for Adaptive Research

Sex: All

Age: 18+

Code: NCT03970447

Phase 2, Phase 3, Recruiting
Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Orange CA, Chino CA, Glendale CA, West Hills CA,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase 2, Recruiting
Active & Responsive

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for
Macular Degeneration, Age-Related Macular Degeneration,
Location: Santa Ana CA, Encino CA, Mountain View CA, Gilbert AZ,
Sponsor: EyeBiotech Ltd.

Sex: All

Age: 50+

Code: NCT07496567

Phase 2, Phase 3, Recruiting
Active & Responsive

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for
Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver,
Location: Orange CA, Irvine CA, Duarte CA, Scottsdale AZ,
Sponsor: Massive Bio, Inc.

Sex: All

Age: 0+

Code: NCT03452774

Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

for
Major Depressive Disorder (MDD)
Location: Orange CA, Garden Grove CA, Redlands CA, Las Vegas NV,
Sponsor: Vanda Pharmaceuticals

Sex: All

Age: 18 - 65

Code: NCT06830044

Phase 3, Recruiting
Active & Responsive

Suramin for the Treatment of Autism Trial: KZ101 in a Male Pediatric Population With Autism Spectrum Disorder (ASD)

for
Autism Spectrum Disorder (ASD)
Location: Orange CA, Baltimore MD
Sponsor: Children's Hospital of Orange County

Sex: Male

Age: 5 - 14

Code: NCT06866275

Phase 2, Recruiting
Active & Responsive

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Orange CA, Irvine CA, Los Angeles CA, Beverly Hills CA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05136196

Phase 2, Recruiting
Active & Responsive

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for
Platinum-resistant Ovarian Cancer,
Location: Orange CA, Newport Beach CA, Duarte CA, La Jolla CA,
Sponsor: Genelux Corporation

Sex: Female

Age: 18+

Code: NCT05281471

Phase 3, Recruiting
Active & Responsive

Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

for
Unresectable or Metastatic Hepatocellular Carcinoma,
Location: Orange CA, Irvine CA, Los Angeles CA, Santa Monica CA,
Sponsor: CatalYm GmbH

Sex: All

Age: 18 - 70+

Code: NCT07219459

Phase 2, Recruiting
Active & Responsive

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

for
Cutaneous Melanoma
Location: Orange CA, Irvine CA, Los Angeles CA, Loma Linda CA,
Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All

Age: 70+

Code: NCT07068074

Phase 3, Recruiting
Active & Responsive

Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)

for
Esophageal Carcinoma, Gastric Cancer (Diagnosis),
Location: Orange CA
Sponsor: University of California, Irvine

Sex: All

Age: 18+

Code: NCT07795749

Phase 2, Recruiting
Active & Responsive

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

for
Ovarian Cancer, Cognitive Impairment
Location: Orange CA
Sponsor: University of California, Irvine

Sex: Female

Age: 18+

Code: NCT04520139

Phase 1, Phase 2, Recruiting
Active & Responsive

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for
Colorectal Cancer
Location: Orange VA, Whittier CA, Los Angeles CA, La Jolla CA,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06562543

Recruiting
Active & Responsive

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for
Diabetes Mellitus, Type 2, Hypertension,
Location: Orange CA, Long Beach CA, Torrance CA, Pomona CA,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07064473

Phase 3, Recruiting
Active & Responsive

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease

for
Graves' Disease, Graves Disease
Location: Orange CA, Pasadena CA, Carlsbad CA, San Jose CA,
Sponsor: argenx

Sex: All

Age: 18+

Code: NCT07570316

Phase 3, Recruiting