Discover 3,560 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Orange County offers clinical trials for a variety of conditions, including high blood pressure, heart disease, and skin disorders such as eczema, alopecia, and psoriasis. The city’s medical institutions are actively recruiting both healthy volunteers, as well as those with specific health needs to participate in studies that could improve treatments and outcomes for these, and many other widespread health issues.
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Results: 3,560
Featured
A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years
for
Chronic Migraine
Location: Anaheim CA, Long Beach CA, Oceanside CA, Fresno CA,
Sponsor: AbbVie
Sex: All
Age: 12 - 17
Code: NCT06810505
Phase3, Recruiting
Featured
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)
for
Migraine
Location: Anaheim CA, La Palma CA, Winnetka CA, Oceanside CA,
Sponsor: AbbVie
Sex: All
Age: 6 - 17
Code: NCT05125302
Phase3, Recruiting
Featured
A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine
for
Episodic Migraine
Location: Anaheim CA, Long Beach CA, San Jose CA, Walnut Creek CA,
Sponsor: AbbVie
Sex: All
Age: 6 - 17
Code: NCT05711394
Phase3, Recruiting
Featured
A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant in Participants With ER+/HER2- Early Breast Cancer Who Are Intolerant to Adjuvant Aromatase Inhibitor Therapy (novERA Breast Cancer)
for
Early Breast Cancer
Location: Fountain Valley CA, Sterling Heights MI
Sponsor: Genentech, Inc.
Sex: Female
Age: 18+
Code: NCT07541079
Phase3, Recruiting
Featured
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
for
Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
Location: Irvine CA, Orange CA, Newport Beach CA, Los Angeles CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT06793215
Phase3, Recruiting
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Featured
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
for
Atherosclerosis
Location: Irvine CA, Beverly Hills CA, West Hills CA,
Sponsor: Genentech, Inc.
Sex: All
Age: 18+
Code: NCT07448038
Phase2, Recruiting
Featured
A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer
for
Breast Cancer
Location: Anaheim CA, Palo Alto CA, Pierre SD, Mitchell SD,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT07405801
Phase2, Recruiting
Featured
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
for
Non Small Cell Lung Cancer
Location: Huntington Beach CA, Irvine CA, Duarte CA, Lancaster CA,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT04928846
Phase3, Recruiting
FeaturedNew
A Study to Assess the Safety and Efficacy of AGN-151586 Injections for the Treatment of Moderate to Severe Forehead Lines (FHL) in Adult Participants
for
Forehead Lines
Location: Newport Beach CA, Pflugerville TX, Wilmington NC,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07730554
Phase2, Recruiting
FeaturedNew
Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
for
Crohn's Disease, Ulcerative Colitis
Location: Anaheim CA, Los Alamitos CA, Rialto CA, Lancaster CA,
Sponsor: AbbVie
Sex: All
Age: 18 - 70+
Code: NCT07697456
Phase2, Recruiting
Featured
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
for
Moderately to Severely Active Crohns Disease
Location: Newport Beach CA, Santa Clarita CA, Lancaster CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 16 - 70+
Code: NCT06819891
Phase3, Recruiting
Featured
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations
for
Non Small Cell Lung Carcinoma
Location: Fullerton CA, Santa Monica CA, Oxnard CA,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT06772623
Phase1, Phase2, Recruiting
Featured
Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL
for
Relapsed or Refractory Aggressive B-Cell Non-Hodgkins Lymphoma
Location: Fullerton CA, Torrance CA, Glendale CA, Los Angeles CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT06806033
Phase2, Recruiting
Featured
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer,
Location: Irvine CA, Santa Monica CA, Duarte CA, Stanford CA,
Sponsor: Hoffmann-La Roche
Sex: Female
Age: 18+
Code: NCT04802759
Phase1, Phase2, Recruiting
Featured
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
for
Metastatic Breast Cancer
Location: Irvine CA, Corona CA, Duarte CA, Burbank CA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT05894239
Phase3, Recruiting
Featured
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
for
Small Cell Lung Cancer
Location: Irvine CA, Duarte CA, Goodyear AZ, Eugene OR, Tyler TX,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07365241
Phase3, Recruiting
Featured
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma
for
Multiple Myeloma
Location: Irvine CA, Duarte CA, Cincinnati OH, Atlanta GA,
Sponsor: Hoffmann-La Roche
Sex: All
Age: 18+
Code: NCT07555938
Phase3, Recruiting
Featured
A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors
for
Advanced Squamous Tumors
Location: Irvine CA, Duarte CA, Irving TX, Chicago IL,
Sponsor: AbbVie
Sex: All
Age: 18+
Code: NCT07241039
Phase1, Recruiting
Featured
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
for
Breast Cancer
Location: Irvine CA, Duarte CA, La Jolla CA, San Diego CA,
Sponsor: Genentech, Inc.
Sex: All
Age: 18+
Code: NCT07100106
Phase1, Phase2, Recruiting
Featured
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
for
Breast Cancer
Location: Irvine CA, Los Alamitos CA, Long Beach CA, Burbank CA,