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Paid Clinical Trials Orange County

Discover 3,560 paid clinical trials in Orange County, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Los Angeles CA, San Diego CA, San Francisco CA, Reno NV,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase2, Recruiting
Active & Responsive

An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for
Plaque Psoriasis
Location: Santa Ana CA, Fountain Valley CA, Los Angeles CA,
Sponsor: Oruka Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07449702

Phase2, Recruiting
Active & Responsive

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

for
Type 2 Diabetes
Location: Santa Ana CA, Phoenix AZ, Rexburg ID, Redmond WA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT06897475

Phase2, Recruiting
Active & Responsive

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

for
Obesity or Overweight
Location: Santa Ana CA, Rolling Hills Estates CA, Rialto CA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07575399

Phase3, Recruiting
Active & Responsive

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

for
Obesity, Overweight
Location: Santa Ana CA, Fountain Valley CA, Long Beach CA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07684235

Phase3, Recruiting

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Active & Responsive

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

for
Obesity, Overweight
Location: Santa Ana CA, Fountain Valley CA, Tustin CA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07321886

Phase3, Recruiting
Active & Responsive

Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

for
Hemophilia B
Location: Orange CA, Memphis TN, Atlanta GA, Ann Arbor MI,
Sponsor: CSL Behring

Sex: Male

Age: 11 - 17

Code: NCT07080905

Phase3, Recruiting
Active & Responsive

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

for
Von Willebrand Disease, Type 3, Concomitant VWD and Hemophilia
Location: Orange CA, Redwood City CA, Seattle WA, Kansas City MO,
Sponsor: Bleeding and Clotting Disorders Institute Peoria, Illinois

Sex: All

Age: 0 - 70+

Code: NCT05500807

Phase1, Recruiting
Active & Responsive

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for
Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation
Location: Orange CA, Long Beach CA, La Jolla CA, Sacramento CA,
Sponsor: Chris Goss

Sex: All

Age: 6+

Code: NCT05548283

Recruiting
Active & Responsive

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

for
Langerhan's Cell Histiocytosis, Juvenile Xanthogranuloma,
Location: Orange CA, Phoenix AZ, San Francisco CA, Dallas TX,
Sponsor: Carl Allen

Sex: All

Age: 0+

Code: NCT04079179

Phase2, Recruiting
Active & Responsive

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: Orange CA, Long Beach CA, Las Vegas NV, Phoenix AZ,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 21

Code: NCT05183035

Phase3, Recruiting
Active & Responsive

Global Patient Registry to Monitor Long-term Safety and Effectiveness of Increlex® in Children and Adolescents With Severe Primary Insulin-like Growth Factor-1 Deficiency (SPIGFD).

for
IGF1 Deficiency
Location: Orange CA, Cincinnati OH, Miami FL
Sponsor: Esteve Pharmaceuticals, S.A.

Sex: All

Age: 2 - 18

Code: NCT00903110

Recruiting
Active & Responsive

A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

for
Dravet Syndrome
Location: Orange CA, Los Angeles CA, Phoenix AZ, San Francisco CA,
Sponsor: Stoke Therapeutics, Inc

Sex: All

Age: 2 - 17

Code: NCT06872125

Phase3, Recruiting
Active & Responsive

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for
Lymphoblastic Leukemia
Location: Orange CA, Los Angeles CA, Madera CA, Phoenix AZ,
Sponsor: Tanja Andrea Gruber

Sex: All

Age: 0 - 1

Code: NCT05848687

Phase1, Phase2, Recruiting
Active & Responsive

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for
Autoimmune Diseases, Ulcerative Colitis, Multiple Sclerosis,
Location: Orange CA, Sherman Oaks CA, Skokie IL, Lexington KY,
Sponsor: TScan Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06587828

Recruiting
Active & Responsive

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

for
Sickle Cell Disease
Location: Orange CA, Houston TX, Flowood MS, Chicago IL,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 12 - 70+

Code: NCT06439082

Phase3, Recruiting
Active & Responsive

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for
Glioblastoma
Location: Orange CA, Los Angeles CA, La Jolla CA,
Sponsor: Global Coalition for Adaptive Research

Sex: All

Age: 18+

Code: NCT03970447

Phase2, Phase3, Recruiting
Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Orange CA, Chino CA, Glendale CA, La Jolla CA,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase2, Recruiting
Active & Responsive

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for
Macular Degeneration, Age-Related Macular Degeneration,
Location: Santa Ana CA, Encino CA, Mountain View CA, Gilbert AZ,
Sponsor: EyeBiotech Ltd.

Sex: All

Age: 50+

Code: NCT07496567

Phase2, Phase3, Recruiting
Active & Responsive

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for
Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver,
Location: Orange CA, Irvine CA, Duarte CA, Scottsdale AZ,
Sponsor: Massive Bio, Inc.

Sex: All

Age: 0+

Code: NCT03452774

Recruiting