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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Well-being in IBS: Strengths and Happiness (WISH) 2.0

for
Irritable Bowel Syndrome
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06866106

Recruiting
Active & Responsive

A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

for
Fuchs Endothelial Corneal Dysfunction,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 20 - 70+

Code: NCT07780890

Recruiting
Active & Responsive

Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Support Therapy in Functional Dyspepsia

for
Functional Dyspepsia
Location: Boston MA
Sponsor: Spaulding Rehabilitation Hospital

Sex: All

Age: 18 - 65

Code: NCT06360900

Recruiting
Active & Responsive

A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

for
Amputation
Location: Boston MA, Cambridge MA, Bethesda MD
Sponsor: Brigham and Women's Hospital

Sex: All

Age: 18 - 65

Code: NCT03882073

Recruiting
Active & Responsive

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

for
REM Sleep Behavior Disorder
Location: Boston MA, Aurora CO
Sponsor: Yale University

Sex: All

Age: 50 - 70+

Code: NCT06996652

Phase2, Recruiting

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Active & Responsive

US Benchmarking Clinical Study

for
HFpEF - Heart Failure With Preserved Ejection Fraction, HFmrEF,
Location: Boston MA
Sponsor: eMyosound SAS

Sex: All

Age: 60+

Code: NCT07215715

Recruiting
Active & Responsive

Ultrasound Stimulation for Patients in a Disorder of Consciousness

for
Consciousness Disorders,
Location: Boston MA, Pomona CA, Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: All

Age: 18 - 70+

Code: NCT06939348

Recruiting
Active & Responsive

PDT For Induction Therapy For Head And Neck Cancer

for
Squamous Cell Carcinoma,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07214987

Phase2, Recruiting
Active & Responsive

Resilient Families Feasibility Trial

for
Parents
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07383948

Recruiting
Active & Responsive

The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium

for
Delirium, Postoperative, Delirium in Old Age
Location: Boston MA, New York NY, Columbus OH
Sponsor: Beth Israel Deaconess Medical Center

Sex: All

Age: 60+

Code: NCT06721819

Phase3, Recruiting
Active & Responsive

Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for
Optic Neuritis, Myelitis, Myelitis, Transverse
Location: Boston MA, North Haven CT, New York NY, Baltimore MD,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT07100990

Phase3, Recruiting
Active & Responsive

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for
Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma,
Location: Boston MA, New Haven CT, New York NY, New Brunswick NJ,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT05303519

Phase3, Recruiting
Active & Responsive

A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

for
Dravet Syndrome
Location: Boston MA, New York NY, Rochester NY,
Sponsor: Stoke Therapeutics, Inc

Sex: All

Age: 2 - 17

Code: NCT06872125

Phase3, Recruiting
Active & Responsive

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Boston MA, New York NY, Durham NC
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07024615

Phase1, Recruiting
Active & Responsive

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Boston MA, Fairfax VA, Cleveland OH, Zion IL,
Sponsor: Terremoto Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07109726

Phase1, Phase2, Recruiting
Active & Responsive

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for
Immune Thrombocytopenic Purpura (ITP)
Location: Boston MA, Philadelphia PA, Bethesda MD,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06722235

Phase3, Recruiting
Active & Responsive

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Boston MA, Hackensack NJ, New York NY,
Sponsor: ModernaTX, Inc.

Sex: All

Age: 12+

Code: NCT05533697

Phase1, Phase2, Recruiting
Active & Responsive

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for
Advanced Melanoma
Location: Boston MA, Lake Success NY, New York NY,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT05549297

Phase3, Recruiting
Active & Responsive

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for
Glioblastoma
Location: Boston MA, New Haven CT, New York NY, Montreal, Toronto,
Sponsor: Global Coalition for Adaptive Research

Sex: All

Age: 18+

Code: NCT03970447

Phase2, Phase3, Recruiting
Active & Responsive

Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma

for
Melanoma, Unresectable Melanoma
Location: Boston MA, New York NY, Los Angeles CA
Sponsor: NYU Langone Health

Sex: All

Age: 18 - 70+

Code: NCT05428007

Phase2, Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

Local regulations and guidelines

Benefits of participating in clinical trials

How to enroll in a clinical trial in Boston