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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Mechanisms Underlying Efficacy of Prolonged Exposure

for
Post Traumatic Stress Disorder
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05788302

Recruiting
Active & Responsive

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for
PIK3CA Mutation, Solid Tumor, Adult,
Location: Boston MA, New Haven CT, New York NY, New Brunswick NJ,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05216432

Phase1, Recruiting
Active & Responsive

Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia

for
Avoidant/Restrictive Food Intake Disorder, Dyspepsia,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05587127

Recruiting
Active & Responsive

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for
Treatment Resistant Depression
Location: Boston MA, Nashua NH, New York NY, Woodbury NY,
Sponsor: LivaNova

Sex: All

Age: 18+

Code: NCT03887715

Recruiting
Active & Responsive

Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity

for
Obesity
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT05933499

Phase2, Recruiting

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Active & Responsive

Nutrition for Precision Health, Powered by the All of Us

for
Nutrition, Health, Dietary Habits
Location: Boston MA, Chapel Hill NC, Kannapolis NC, Chicago IL,
Sponsor: RTI International

Sex: All

Age: 18+

Code: NCT05701657

Recruiting
Active & Responsive

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for
Treatment Resistant Depression
Location: Boston MA, New York NY, New Brunswick NJ,
Sponsor: Abbott Medical Devices

Sex: All

Age: 22 - 70

Code: NCT06423430

Recruiting
Active & Responsive

Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

for
Arthritis, Unstable Radial Head,
Location: Boston MA, Allentown PA, Dayton OH, Carmel IN,
Sponsor: Aptis Medical

Sex: All

Age: 18 - 70+

Code: NCT05796908

Recruiting
Active & Responsive

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for
Stroke, Stroke, Acute, Stroke, Ischemic
Location: Boston MA, Burlington MA, Springfield MA, New Haven CT,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT05338697

Recruiting
Active & Responsive

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for
Parkinson Disease
Location: Boston MA, New Haven CT, New York NY, Montreal,
Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All

Age: 30+

Code: NCT04477785

Recruiting
Active & Responsive

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

for
Prostate Carcinoma
Location: Boston MA, Philadelphia PA, Chicago IL, Seattle WA,
Sponsor: University of Washington

Sex: Male

Age: 40+

Code: NCT04472338

Recruiting
Active & Responsive

Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

for
Overweight, PreDiabetes, Diabetes Type 2, Obesity
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 65

Code: NCT05799222

Recruiting
Active & Responsive

Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)

for
Chronic Neuropathic Pain
Location: Boston MA, New York NY, Baltimore MD, Richmond VA,
Sponsor: Sangamo Therapeutics

Sex: All

Age: 18+

Code: NCT06980948

Phase1, Phase2, Recruiting
Active & Responsive

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for
Heart Failure, Heart Diseases, Cardiovascular Diseases,
Location: Boston MA, Portland ME, Manhasset NY, The Bronx NY,
Sponsor: Abbott Medical Devices

Sex: All

Age: 18+

Code: NCT06526195

Recruiting
Active & Responsive

Global Paradise System US Post Approval Study

for
Hypertension, Cardiovascular Diseases, Vascular Diseases
Location: Boston MA, Bridgeport CT, Albany NY, Stony Brook NY,
Sponsor: ReCor Medical, Inc.

Sex: All

Age: 18+

Code: NCT06297291

Recruiting
Active & Responsive

Assessment of CCM in HF With Higher Ejection Fraction

for
Heart Failure, Heart Failure With Preserved Ejection Fraction,
Location: Boston MA, Hartford CT, Danbury CT, Poughkeepsie NY,
Sponsor: Impulse Dynamics

Sex: All

Age: 18+

Code: NCT05064709

Recruiting
Active & Responsive

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for
Frontotemporal Lobar Degeneration (FTLD),
Location: Boston MA, New York NY, Philadelphia PA, Baltimore MD,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04363684

Recruiting
Active & ResponsiveNew

Effects of Estrogen on Heart Health in Women With Primary Ovarian Insufficiency

for
Primary Ovarian Insufficiency, Premature Menopause,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: Female

Age: 30 - 40

Code: NCT06866119

Recruiting
Active & Responsive

FOG-001 in Locally Advanced or Metastatic Solid Tumors

for
Cancer, Colorectal Cancer, Solid Tumor,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: Parabilis Medicines, Inc.

Sex: All

Age: 18+

Code: NCT05919264

Phase1, Phase2, Recruiting
Active & Responsive

A One-Arm Open Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior

for
Suicide Attempt, Suicide Ideation
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06967545

Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

Local regulations and guidelines

Benefits of participating in clinical trials

How to enroll in a clinical trial in Boston