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Paid Clinical Trials Boston

Discover 3,070 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Study of REM-422 in Patients With AML or Higher Risk MDS

for
Myelodysplastic Syndromes,
Location: Boston MA, New York NY, Tampa FL, Houston TX, Duarte CA
Sponsor: Remix Therapeutics

Sex: All

Age: 18+

Code: NCT06297941

Phase1, Recruiting
Active & Responsive

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

for
Mesial Temporal Lobe Epilepsy
Location: Boston MA, Lebanon NH, Hackensack NJ, New Brunswick NJ,
Sponsor: UniQure Biopharma B.V.

Sex: All

Age: 18 - 70+

Code: NCT06063850

Phase1, Phase2, Recruiting
Active & Responsive

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

for
Alzheimer Disease, Family Members
Location: Boston MA, Cambridge MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 55 - 70+

Code: NCT05776641

Recruiting
Active & Responsive

Intermuscular Coherence as a Biomarker for ALS

for
Amyotrophic Lateral Sclerosis
Location: Boston MA, St Louis MO, Miami FL
Sponsor: University of Chicago

Sex: All

Age: 20 - 70+

Code: NCT05104710

Recruiting
Active & Responsive

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for
Hereditary Hemorrhagic Telangiectasia,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: Cure HHT

Sex: All

Age: 0+

Code: NCT06259292

Recruiting

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Active & Responsive

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for
Carcinoma, Non-Small-Cell Lung
Location: Boston MA, Norwich CT, New Haven CT, Valhalla NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06623422

Phase3, Recruiting
Active & Responsive

REcovery From DEXmedetomidine-induced Unconsciousness

for
Anesthesia, Healthy, Consciousness, Level Altered
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 65

Code: NCT06003127

Recruiting
Active & Responsive

Pivotal Study of N-acetyl-L-leucine for CACNA1A

for
CACNA1A, Spinocerebellar Ataxia Type 6, Episodic Ataxia Type 2,
Location: Boston MA, Baltimore MD, Houston TX
Sponsor: IntraBio Inc

Sex: All

Age: 4+

Code: NCT07221292

Phase3, Recruiting
Active & Responsive

Identifying Multidimensional Signatures of Gastric Interoception in Functional Dyspepsia

for
Functional Dyspepsia, Anorexia Nervosa
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 65

Code: NCT07772167

Recruiting
Active & Responsive

GBPDC: Gut-Brain in PD Consortium Master Protocol

for
Parkinson Disease (PD), PARKINSON DISEASE (Disorder),
Location: Boston MA, Chicago IL, Rochester MN, Stanford CA
Sponsor: Duke University

Sex: All

Age: 21 - 70+

Code: NCT07567794

Recruiting
Active & Responsive

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

for
Lymphoma, Non-Hodgkin, B-cell Lymphoma,
Location: Boston MA, New Haven CT, New York NY, Philadelphia PA,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07101328

Phase1, Recruiting
Active & Responsive

Brostrom Chronic Lateral Ankle Instability Repairs Augmented With BioBrace®

for
Lateral Ankle Instability, Chronic Lateral Ankle Instability,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 65

Code: NCT07708584

Recruiting
Active & Responsive

Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

for
Unresectable or Metastatic Hepatocellular Carcinoma,
Location: Boston MA, Atlanta GA, Peoria IL, Orange CA, Irvine CA,
Sponsor: CatalYm GmbH

Sex: All

Age: 18 - 70+

Code: NCT07219459

Phase2, Recruiting
Active & Responsive

PrP-targeting siRNA Safety & Mechanism Study

for
Prion Disease
Location: Boston MA, New York NY, Cleveland OH, Nashville TN,
Sponsor: Broad Institute of MIT and Harvard

Sex: All

Age: 18+

Code: NCT07444580

Phase1, Recruiting
Active & Responsive

A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

for
FGFR2 Gene Fusion/Rearrangement, Other Solid Tumors, Adult
Location: Boston MA, New York NY, Chicago IL, Tampa FL,
Sponsor: Elevar Therapeutics

Sex: All

Age: 18+

Code: NCT07359820

Phase2, Recruiting
Active & Responsive

A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma

for
Multiple Myeloma in Relapse, Myeloma Multiple,
Location: Boston MA, Hackensack NJ, Atlanta GA, Tampa FL,
Sponsor: Kelonia Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07075185

Phase1, Recruiting
Active & Responsive

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for
Glioblastoma (GBM), Newly Diagnosed Glioblastoma, GBM,
Location: Boston MA, New Haven CT, Lake Success NY, The Bronx NY,
Sponsor: Black Diamond Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT07326566

Phase2, Recruiting
Active & Responsive

Momelotinib During and After HCT in Myelofibrosis

for
Myelofibrosis, Hematopoietic Cell Transplantation (HCT)
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT07104799

Phase1, Recruiting
Active & Responsive

A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for
Immune Thrombocytopenic Purpura (ITP)
Location: Boston MA, Portland OR
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06948318

Phase3, Recruiting
Active & Responsive

Study to Assess Safety, Efficacy and Persistence of ACE1831, in Subjects With IgG4-Related Disease

for
IgG4 Related Disease
Location: Boston MA, Atlanta GA
Sponsor: Acepodia Biotech, Inc.

Sex: All

Age: 18+

Code: NCT07061938

Phase1, Phase2, Recruiting

With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.

Why choose Boston for clinical trials?

Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.

The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.

Common conditions studied in Boston

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