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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

for
Lower Extremity Acute Limb Ischemia, LE ALI
Location: Chapel Hill NC, Raleigh NC, Concord NC,
Sponsor: Penumbra Inc.

Sex: All

Age: 18+

Code: NCT06747117

Recruiting
Active & Responsive

CARED : A Novel Rapid Treatment Paradigm for Depression

for
Major Depressive Disorder
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 70

Code: NCT07507370

Recruiting
Active & Responsive

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for
Recurrent Head and Neck Squamous Cell Carcinoma,
Location: Chapel Hill NC, Reidsville NC, Greensboro NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT04671667

Phase2, Recruiting
Active & Responsive

A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

for
Lung Non-Small Cell Carcinoma
Location: Chapel Hill NC, Washington PA, Greensburg PA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: All

Age: 18+

Code: NCT07293247

Phase2, Recruiting
Active & Responsive

PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease

for
Breast Cancer, Residual Disease,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT07069595

Phase2, Recruiting

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Active & ResponsiveNew

Daily Upgrade Trial

for
Healthy Women
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: Female

Age: 25 - 45

Code: NCT07792603

Recruiting
Active & Responsive

Tafasitamab and Rituximab for Front-Line Treatment of Post-Transplant Lymphoproliferative Disorder

for
Monomorphic B-Cell Post-Transplant Lymphoproliferative Disorder,
Location: Hillsborough NC, Columbus OH, New Brunswick NJ,
Sponsor: Timothy Voorhees

Sex: All

Age: 18+

Code: NCT05786040

Phase2, Recruiting
Active & Responsive

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for
Spinal Muscular Atrophy (SMA)
Location: Hillsborough NC, Hartford CT, Kissimmee FL, Boston MA,
Sponsor: argenx

Sex: All

Age: 5 - 17

Code: NCT07287982

Phase2, Recruiting
Active & Responsive

VTP-1000 in Adults With Celiac Disease

for
Celiac Disease
Location: Raleigh NC, Richmond VA, Baltimore MD, Columbus OH,
Sponsor: Barinthus Biotherapeutics

Sex: All

Age: 18 - 70

Code: NCT06310291

Early_phase1, Recruiting
Active & Responsive

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

for
Hypertension
Location: Raleigh NC, Richmond VA, Mt. Pleasant SC, Lancaster PA,
Sponsor: SoniVie Inc.

Sex: All

Age: 22 - 70+

Code: NCT06559891

Recruiting
Active & Responsive

SELUTION 4 De Novo Small Vessel IDE Trial

for
Coronary Artery Disease
Location: Raleigh NC, Richmond VA, Charleston WV,
Sponsor: M.A. Med Alliance S.A.

Sex: All

Age: 18+

Code: NCT05946629

Recruiting
Active & Responsive

Contour Neurovascular System™ ContiNued Access Investigational Device EXempTion (IDE) Trial (NEXT Trial)

for
Cerebral Aneurysms
Location: Raleigh NC, Charleston SC, Philadelphia PA,
Sponsor: Cerus Endovascular, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06693011

Recruiting
Active & Responsive

Fertilo In Vitro Research Study and Trial

for
In Vitro Maturation of Oocytes
Location: Raleigh NC, Charlotte NC, Rockville MD, New York NY,
Sponsor: Gameto, Inc.

Sex: Female

Age: 18 - 35

Code: NCT06858111

Phase3, Recruiting
Active & Responsive

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for
Major Depressive Disorder
Location: Raleigh NC, Towson MD, Stone Mountain GA,
Sponsor: Syndeio Biosciences, Inc

Sex: All

Age: 18 - 64

Code: NCT07115329

Phase2, Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for
Diabetic Peripheral Neuropathic Pain
Location: Raleigh NC, Winston-Salem NC, Richmond VA,
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 18 - 70+

Code: NCT06628908

Phase3, Recruiting
Active & Responsive

Study of EVO756 in Adults With Migraine

for
Migraine
Location: Raleigh NC, Crab Orchard WV, Asheville NC,
Sponsor: Evommune, Inc.

Sex: All

Age: 18 - 64

Code: NCT07616128

Phase2, Recruiting
Active & Responsive

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

for
Psoriasis, Overweight or Obesity
Location: Cary NC, Huntersville NC, Columbia SC, Rockville MD,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06857942

Recruiting
Active & Responsive

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for
Obesity, Heart Failure
Location: Apex NC, Concord NC, Statesville NC, Fort Mill SC,
Sponsor: Novo Nordisk A/S

Sex: All

Age: 18+

Code: NCT07567001

Phase3, Recruiting
Active & Responsive

Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

for
Schizophrenia
Location: Cary NC, Wilmington NC, Philadelphia PA, Atlanta GA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07379827

Recruiting
Active & Responsive

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for
Major Depressive Disorder (MDD),
Location: Cary NC, North Canton OH, Brooklyn NY, Orlando FL,
Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All

Age: 18 - 65

Code: NCT07284667

Phase2, Recruiting