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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for
Heart Failure, Heart Diseases, Cardiovascular Diseases,
Location: Chapel Hill NC, Charlotte NC, Charlottesville VA,
Sponsor: Abbott Medical Devices

Sex: All

Age: 18+

Code: NCT06526195

Recruiting
Active & Responsive

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for
Diabetes Mellitus, Type 2, Hypertension,
Location: Chapel Hill NC, Cary NC, Savannah GA, Winston-Salem NC,
Sponsor: Boehringer Ingelheim

Sex: All

Age: 18+

Code: NCT07064473

Phase3, Recruiting
Active & Responsive

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for
Frontotemporal Lobar Degeneration (FTLD),
Location: Chapel Hill NC, Bethesda MD, Baltimore MD,
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04363684

Recruiting
Active & Responsive

Nephrotic Syndrome Study Network

for
Minimal Change Disease (MCD), Membranous Nephropathy,
Location: Chapel Hill NC, Charlotte NC, Charleston SC,
Sponsor: University of Michigan

Sex: All

Age: 0 - 70+

Code: NCT01209000

Recruiting
Active & Responsive

Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

for
Barrett Esophagus, Gastroesophageal Reflux,
Location: Chapel Hill NC, Baltimore MD, Cleveland OH, Aurora CO
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 50+

Code: NCT06687603

Recruiting

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Active & Responsive

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

for
HER2-positive Metastatic Breast Cancer
Location: Chapel Hill NC, Washington D.C. DC, Baltimore MD,
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06551116

Recruiting
Active & Responsive

Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

for
Polycythemia Vera
Location: Chapel Hill NC, Bethesda MD, Roanoke VA, Cleveland OH,
Sponsor: Italfarmaco

Sex: All

Age: 18+

Code: NCT06093672

Phase3, Recruiting
Active & Responsive

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for
Hereditary Hemorrhagic Telangiectasia,
Location: Chapel Hill NC, Augusta GA, Philadelphia PA,
Sponsor: Cure HHT

Sex: All

Age: 0+

Code: NCT06259292

Recruiting
Active & Responsive

DILIN - Prospective Study

for
Liver Diseases
Location: Chapel Hill NC, Bethesda MD, Philadelphia PA,
Sponsor: Duke University

Sex: All

Age: 2+

Code: NCT00345930

Recruiting
Active & Responsive

Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART

for
Diabetes type1, Diabetes Mellitus, Type 1, Diabetes, Autoimmune,
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 30+

Code: NCT06405373

Recruiting
Active & Responsive

Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults

for
Autism Spectrum Disorder, Depression, Anxiety
Location: Chapel Hill NC, Charlottesville VA
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18+

Code: NCT06060860

Recruiting
Active & Responsive

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

for
Oropharyngeal Squamous Cell Carcinoma, Carcinoma, Squamous Cell,
Location: Chapel Hill NC, North Charleston SC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04564989

Recruiting
Active & Responsive

Safety of MOON101 for the Treatment of Peanut Allergy

for
Peanut Allergy
Location: Chapel Hill NC, Atlanta GA, Ann Arbor MI,
Sponsor: Moonlight Therapeutics, Inc.

Sex: All

Age: 4 - 55

Code: NCT07580898

Phase1, Recruiting
Active & Responsive

RESTORE: Comparing Two Approaches to Repeat TT Surgery Performed by Integrated Eye Care Workers (IECWs)

for
Trachoma, Eye Diseases, Trichiasis
Location: Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18+

Code: NCT07322302

Recruiting
Active & Responsive

PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

for
Bronchopulmonary Dysplasia (BPD), Premature Births,
Location: Chapel Hill NC, Greenville NC, Amherst MA,
Sponsor: Duke University

Sex: All

Age: 0

Code: NCT07101640

Phase1, Phase2, Recruiting
Active & Responsive

NEPTUNE Match Study

for
Nephrotic Syndrome in Children,
Location: Chapel Hill NC, Charlotte SC, Baltimore MD,
Sponsor: University of Michigan

Sex: All

Age: 1 - 70+

Code: NCT04571658

Recruiting
Active & Responsive

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

for
Ulcerative Colitis (UC), Crohn's Disease (CD),
Location: Chapel Hill NC, Winston-Salem NC, Charlotte NC,
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18+

Code: NCT07237516

Recruiting
Active & Responsive

EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

for
PIK3CA-related Overgrowth Spectrum (PROS)
Location: Chapel Hill NC, Pittsburgh PA, Columbus OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 2 - 70+

Code: NCT06997588

Phase2, Recruiting
Active & Responsive

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

for
AML With Gene Mutations
Location: Chapel Hill NC, College Park MD, Atlanta GA,
Sponsor: Lomond Therapeutics Holdings, Inc.

Sex: All

Age: 18+

Code: NCT06366789

Phase1, Recruiting
Active & Responsive

Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study

for
Breast Cancer, Breast Neoplasms
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: Female

Age: 20 - 70+

Code: NCT07214610

Recruiting