Background illustration for clinical trials search

Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

Filter
2

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

for
Transthyretin Amyloidosis, ATTR-CM, ATTRv-PN, ATTR, ATTR-Mixed,
Location: Durham NC, Richmond VA, Greenville SC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06465810

Recruiting

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for
Non-Small Cell Lung Cancer
Location: Durham NC, Chapel Hill NC, Pinehurst NC, Blacksburg VA,
Sponsor: Summit Therapeutics

Sex: All

Age: 18+

Code: NCT06767514

Phase3, Recruiting

Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors

for
Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors,
Location: Durham NC, Washington D.C. DC, Cincinnati OH,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 1 - 70+

Code: NCT05868629

Recruiting

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

for
Myasthenia Gravis, MG, gMG, Generalized Myasthenia Gravis,
Location: Durham NC, Columbus OH, Chattanooga TN, Amherst NY,
Sponsor: argenx

Sex: All

Age: 18+

Code: NCT07294170

Recruiting

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

for
AChR-Ab Seropositive Generalized Myasthenia Gravis,
Location: Durham NC, Columbus OH, Chattanooga TN, Amherst NY,
Sponsor: argenx

Sex: All

Age: 18+

Code: NCT07284420

Phase2, Recruiting

Interested in new trials?

Get alerts for new trials in your area by subscribing now

Subscriber Image

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for
Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma,
Location: Durham NC, Fairfax VA, Cleveland OH, New York NY,
Sponsor: Plexium, Inc.

Sex: All

Age: 18+

Code: NCT07284186

Phase1, Recruiting

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for
Metastatic Clear Cell Renal Cell Carcinoma,
Location: Durham NC, Chapel Hill NC, Charlottesville VA,
Sponsor: Arcus Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT07011719

Phase3, Recruiting

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

for
Cardiovascular, Metabolic Disease, Dyslipidemias,
Location: Durham NC, High Point NC, Jacksonville FL,
Sponsor: CRISPR Therapeutics AG

Sex: All

Age: 18 - 70+

Code: NCT07491172

Phase1, Recruiting

COA-APTIC Cognitive Interview Study of Caregiver and Clinician Assessment of Acute Pain in Infants and Young Children

for
Acute Pain
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06164028

Recruiting

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

for
Systemic Lupus Erythematosus
Location: Durham NC, Washington D.C. DC, Philadelphia PA,
Sponsor: AstraZeneca

Sex: All

Age: 5 - 17

Code: NCT05835310

Phase3, Recruiting

A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18

for
Glycogen Storage Disease Type II Infantile Onset
Location: Durham NC, Pittsburgh PA, Atlanta GA, Cincinnati OH,
Sponsor: Amicus Therapeutics

Sex: All

Age: 0 - 17

Code: NCT04808505

Phase3, Recruiting

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

for
End Stage Kidney Disease
Location: Durham NC, Raleigh NC, Greenville NC, Charlotte NC,
Sponsor: CSL Behring

Sex: All

Age: 18+

Code: NCT05485961

Phase2, Phase3, Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for
Heart Failure and Impaired Kidney Function
Location: Durham NC, Chapel Hill NC, Pinehurst NC, Charlotte NC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06307652

Phase3, Recruiting

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

for
Polymyositis, Dermatomyositis
Location: Durham NC, Charlotte NC, Summerville SC, Charleston SC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06455449

Phase3, Recruiting

A Study of Brepocitinib in Adults With Cutaneous Sarcoidosis

for
Cutaneous Sarcoidosis
Location: Durham NC, Philadelphia PA, Madison WI,
Sponsor: Priovant Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06978725

Phase2, Phase3, Recruiting

A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments

for
Multiple Myeloma
Location: Chapel Hill NC, Wilson NC, Canton OH, Chattanooga TN,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT05714839

Phase1, Phase2, Recruiting

A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

for
Liver Diseases, Alcoholic
Location: Chapel Hill NC, Richmond VA, Detroit MI,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18 - 70

Code: NCT06613698

Phase2, Recruiting

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

for
Colonic Neoplasms, Neoplasms, Colon
Location: Durham NC, Richmond VA, Bethesda MD, Detroit MI,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT05855200

Phase3, Recruiting

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

for
Lung Diseases, Interstitial
Location: Durham NC, Gainesville FL, Philadelphia PA, New York NY,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06572384

Phase3, Recruiting

A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

for
HIV Infections
Location: Durham NC, Greensboro NC, Charlotte NC, Wilmington NC,
Sponsor: ViiV Healthcare

Sex: All

Age: 18+

Code: NCT07202546

Phase2, Recruiting