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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

for
Atherosclerotic Cardiovascular Disease, Overweight, Obesity
Location: Durham NC, Raleigh NC, Greensboro NC, Winston-Salem NC,
Sponsor: Amgen

Sex: All

Age: 45 - 70+

Code: NCT07037433

Phase3, Recruiting
Active & Responsive

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for
NASH - Nonalcoholic Steatohepatitis,
Location: Durham NC, Chapel Hill NC, Raleigh NC, Fayetteville NC,
Sponsor: Akero Therapeutics, Inc

Sex: All

Age: 18 - 70+

Code: NCT06528314

Phase3, Recruiting
Active & Responsive

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for
NASH With Fibrosis, MASH With Fibrosis
Location: Durham NC, Chapel Hill NC, Raleigh NC, Fayetteville NC,
Sponsor: Akero Therapeutics, Inc

Sex: All

Age: 18 - 70+

Code: NCT06215716

Phase3, Recruiting
Active & Responsive

IAP-086-1: A Phase 1 Single Ascending Dose First-Time in Human Study

for
HIV-1-infection
Location: Durham NC, Chapel Hill NC
Sponsor: University of North Carolina, Chapel Hill

Sex: All

Age: 18 - 70

Code: NCT07596888

Phase1, Recruiting
Active & Responsive

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

for
Cancer, PDAC - Pancreatic Ductal Adenocarcinoma,
Location: Durham NC, Fairfax VA, New York NY, Nashville TN,
Sponsor: Alterome Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06835569

Phase1, Recruiting

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Active & Responsive

A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)

for
Urinary Tract Infections
Location: Raleigh NC, Ocala FL, St Louis MO, Hialeah FL, Doral FL,
Sponsor: Locus Biosciences

Sex: Female

Age: 18 - 70+

Code: NCT05488340

Phase2, Recruiting
Active & Responsive

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease

for
Late-onset Pompe Disease
Location: Durham NC, Fairfax VA, St Louis MO, Irvine CA
Sponsor: Denali Therapeutics Inc.

Sex: All

Age: 18 - 70+

Code: NCT07354724

Phase1, Recruiting
Active & Responsive

A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle

for
Chondral Defect, Articular Cartilage Defect
Location: Durham NC, Charlottesville VA, Washington D.C. DC,
Sponsor: Vericel Corporation

Sex: All

Age: 17 - 65

Code: NCT06915233

Phase3, Recruiting
Active & Responsive

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

for
Intestinal Neoplasms, Gastrointestinal Neoplasms,
Location: Durham NC, Cary NC, Raleigh NC, Roanoke VA, Salem VA,
Sponsor: Pfizer

Sex: All

Age: 18+

Code: NCT07222800

Phase3, Recruiting
Active & Responsive

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

for
Parkinson Disease
Location: Durham NC, Asheville NC, Augusta GA, Lexington KY,
Sponsor: Appello Pharmaceuticals, Inc.

Sex: All

Age: 30 - 70+

Code: NCT07432958

Phase2, Recruiting
Active & Responsive

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for
Ductal Carcinoma in Situ
Location: Durham NC, Winston-Salem NC, Richmond VA, Atlanta GA,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female

Age: 18+

Code: NCT06075953

Phase2, Recruiting
Active & ResponsiveNew

Patient Navigation for HER2+ Metastatic Breast Cancer Patients Treated With Tucatinib

for
HER2+ Metastatic Breast Cancer (MBC)
Location: Durham NC
Sponsor: Duke University

Sex: Female

Age: 18+

Code: NCT06983691

Recruiting
Active & Responsive

A Study of PHST001 in Advanced Solid Tumors

for
Advanced Solid Tumors, Ovarian Cancer, Endometrial Cancer,
Location: Durham NC, Fairfax VA, New York NY, Lake Success NY,
Sponsor: Pheast Therapeutics

Sex: All

Age: 18+

Code: NCT06840886

Phase1, Recruiting
Active & Responsive

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for
Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma,
Location: Durham NC, Charlottesville VA, Fairfax VA,
Sponsor: Nuvation Bio Inc.

Sex: All

Age: 18+

Code: NCT05303519

Phase3, Recruiting
Active & Responsive

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer,
Location: Durham NC, Chapel Hill NC, Fairfax VA,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT06901531

Phase3, Recruiting
Active & Responsive

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

for
Pancreatic Ductal Adenocarcinoma
Location: Durham NC, New York NY, Boston MA
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT07024615

Phase1, Recruiting
Active & Responsive

Stress and Menstrual Health

for
Menstrual Dysfunction
Location: Durham NC
Sponsor: Duke University

Sex: Female

Age: 22 - 38

Code: NCT07566260

Recruiting
Active & Responsive

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

for
Surgery-Complications, Anesthesia Complication,
Location: Durham NC, Chapel Hill NC, Winston-Salem NC,
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT05991453

Recruiting
Active & Responsive

ASSESS ALL ALS Study

for
Amyotrophic Lateral Sclerosis
Location: Durham NC, Richmond VA, Washington D.C. DC, Bethseda MD,
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All

Age: 18+

Code: NCT06578195

Recruiting
Active & Responsive

ADRC Clinical Cohort (Alzheimer's Disease)

for
Alzheimer Disease, Mild Cognitive Impairment, Dementia
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 25 - 70+

Code: NCT06703541

Recruiting