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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Active & Responsive

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for
Single Ventricle Heart Disease
Location: Durham NC, Washington D.C. DC, Charleston SC,
Sponsor: Mezzion Pharma Co. Ltd

Sex: All

Age: 12 - 18

Code: NCT05918211

Phase3, Recruiting
Active & Responsive

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for
Pleuropulmonary Blastoma
Location: Durham NC, Chapel Hill NC, Charlottesville VA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT06647953

Phase3, Recruiting
Active & Responsive

CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

for
Cardiac Valve Disease
Location: Durham NC, Greenville NC, Philadelphia PA, Cleveland OH,
Sponsor: Corcym S.r.l

Sex: All

Age: 0+

Code: NCT05002543

Recruiting
Active & Responsive

CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma

for
Relapsed/Refractory Multiple Myeloma
Location: Durham NC, Charlotte NC, Richmond VA, Lexington KY,
Sponsor: Caribou Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT05722418

Phase1, Recruiting
Active & Responsive

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for
Heart Failure With Preserved Ejection Fraction,
Location: Durham NC, Statesville NC, Roanoke VA, Salem VA,
Sponsor: Amgen

Sex: All

Age: 18 - 70+

Code: NCT07037459

Phase3, Recruiting

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Active & Responsive

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

for
Gastric Adenocarcinoma,
Location: Durham NC, Winston-Salem NC, New York NY, Chicago IL,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT05365581

Phase1, Recruiting
Active & Responsive

A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

for
Cytomegalovirus Prophylaxis
Location: Durham NC, Charlotte NC, Pittsburgh PA, Philadelphia PA,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 17

Code: NCT07199465

Phase1, Recruiting
Active & Responsive

HCMT/MM2401: Ph2 Study of Selinexor + Bispecific Antibody for RRMM

for
Multiple Myeloma in Relapse, Multiple Myeloma, Refractory
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06822972

Phase2, Recruiting
Active & Responsive

HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCT

for
Hematologic Malignancy
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06731504

Early_phase1, Recruiting
Active & Responsive

A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

for
Dravet Syndrome
Location: Durham NC, Chapel Hill NC, Charlottesville VA,
Sponsor: Stoke Therapeutics, Inc

Sex: All

Age: 2 - 17

Code: NCT06872125

Phase3, Recruiting
Active & Responsive

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for
Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
Location: Durham NC, Chapel Hill NC, Fayetteville NC,
Sponsor: Cleerly, Inc.

Sex: All

Age: 55+

Code: NCT06112418

Recruiting
Active & Responsive

Retinal Imaging in Neurodegenerative Disease

for
Alzheimer's Disease, Mild Cognitive Impairment,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT03233646

Recruiting
Active & Responsive

A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

for
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP),
Location: Durham NC, Chapel Hill NC, Raleigh NC, Winston-Salem NC,
Sponsor: Takeda

Sex: All

Age: 18+

Code: NCT06747351

Phase3, Recruiting
Active & Responsive

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for
Healthy
Location: Durham NC, North Chesterfield VA, Richmond VA,
Sponsor: Pfizer

Sex: All

Age: 0 - 49

Code: NCT07160244

Phase3, Recruiting
Active & Responsive

Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users

for
Cannabis
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 65

Code: NCT05401929

Recruiting
Active & Responsive

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for
Stroke, Stroke, Acute, Stroke, Ischemic
Location: Durham NC, Charlottesville VA, Columbia SC,
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT05338697

Recruiting
Active & Responsive

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

for
End Stage Renal Disease (ESRD), Kidney Failure,
Location: Durham NC, Raleigh NC, Charlotte NC, Orangeburg SC,
Sponsor: W.L.Gore & Associates

Sex: All

Age: 18 - 70+

Code: NCT04671771

Recruiting
Active & Responsive

UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells

for
Adrenoleukodystrophy, Batten Disease, Mucopolysaccharidosis II,
Location: Durham NC
Sponsor: Joanne Kurtzberg, MD

Sex: All

Age: 0 - 22

Code: NCT02254863

Phase1, Recruiting
Active & Responsive

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for
Mesial Temporal Lobe Epilepsy
Location: Durham NC, Winston-Salem NC, Charlotte NC,
Sponsor: Neurona Therapeutics

Sex: All

Age: 18 - 70+

Code: NCT05135091

Phase3, Recruiting
Active & Responsive

PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

for
Coronary Artery Disease Risk Factors Multiple,
Location: Durham NC, Hiram GA, New York NY, Birmingham AL,
Sponsor: Duke University

Sex: All

Age: 30 - 60

Code: NCT07232069

Phase3, Recruiting