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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy

for
Brain Tumor Related Epilepsy (BTRE)
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT07271966

Recruiting

Planning Grant for TOPS for Breast Cancer Survivors

for
Breast Cancer, Weight Loss
Location: Durham NC
Sponsor: Duke University

Sex: Female

Age: 21 - 70+

Code: NCT06658912

Recruiting

L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma

for
Locally Advanced Cutaneous Squamous Cell Carcinoma
Location: Durham NC, Atlanta GA, Boston MA, Houston TX, Orange CA
Sponsor: Philogen S.p.A.

Sex: All

Age: 18+

Code: NCT07228442

Phase2, Recruiting

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for
Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma,
Location: Durham NC, Chapel Hill NC, Raleigh NC, Cary NC,
Sponsor: National Cancer Institute (NCI)

Sex: Female

Age: 18+

Code: NCT05256225

Phase3, Recruiting

The HOPE Biobank Resource (BMT CTN 2402 HOPE)

for
Aplastic Anemias, Hemoglobinopathies, Bone Marrow Failure
Location: Durham NC, Richmond VA, Atlanta GA, New York NY,
Sponsor: Medical College of Wisconsin

Sex: All

Age: 0+

Code: NCT07227155

Recruiting

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Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for
Anatomic Stage II Breast Cancer AJCC v8,
Location: Durham NC, Raleigh NC, Cary NC, Goldsboro NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT07391774

Phase3, Recruiting

Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs

for
Epilepsy Intractable
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT06545643

Recruiting

IL-17 Blockade to Decrease irAEs (REPLAY)

for
Metastatic Melanoma
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18+

Code: NCT07237594

Phase1, Recruiting

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

for
Diffuse Large B-cell Lymphoma (DLBCL)
Location: Durham NC, Greenville NC, Baltimore MD, Lexington KY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06091865

Phase3, Recruiting

A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

for
Meningioma
Location: Durham NC, Fairfax VA, Columbus OH, Jacksonville FL,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT07428616

Phase2, Recruiting

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Location: Durham NC, Norfolk VA, Pittsburgh PA, Philadelphia PA,
Sponsor: Amgen

Sex: Male

Age: 18+

Code: NCT07493512

Phase1, Recruiting

Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

for
Posterior Fossa Ependymal Tumor
Location: Durham NC, Baltimore MD, Birmingham AL, St Louis MO,
Sponsor: University of California, San Francisco

Sex: All

Age: 1 - 39

Code: NCT07226453

Phase2, Recruiting

SickleFit Exercise and Nutrition Study

for
Sickle Cell Disease, Aging
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 35+

Code: NCT07442851

Recruiting

Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

for
Anaplastic Large Cell Lymphoma, ALK-Negative,
Location: Durham NC, Chapel Hill NC, Kernersville NC,
Sponsor: Eastern Cooperative Oncology Group

Sex: All

Age: 18 - 70+

Code: NCT06724237

Phase3, Recruiting

A Study to Assess the Safety and Effectiveness of the UrOActive® Artificial Urinary sPHincter (AUS)

for
Stress Urinary Incontinence (SUI)
Location: Durham NC, Charlotte NC, Virginia Beach VA,
Sponsor: UroMems SAS

Sex: Male

Age: 22+

Code: NCT06968741

Recruiting

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC,
Location: Durham NC, Fairfax VA, Baltimore MD, Cincinnati OH,
Sponsor: Revolution Medicines, Inc.

Sex: All

Age: 18+

Code: NCT07491445

Phase3, Recruiting

Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC

for
Metastatic Non-Squamous Non-Small Cell Lung Cancer,
Location: Durham NC, New York NY, Mineola NY, Birmingham AL,
Sponsor: CatalYm GmbH

Sex: All

Age: 18+

Code: NCT07246863

Phase2, Recruiting

Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

for
Metastatic Non-Squamous Non-Small Cell Lung Cancer,
Location: Durham NC, Charleston SC, New York NY, Birmingham AL,
Sponsor: CatalYm GmbH

Sex: All

Age: 18+

Code: NCT07098988

Phase2, Recruiting

A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for
Adenovirus Infections
Location: Durham NC, Washington D.C. DC, Philadelphia PA,
Sponsor: SymBio Pharmaceuticals

Sex: All

Age: 0+

Code: NCT07387367

Phase3, Recruiting

129 Xenon Imaging in Patients Treated With Sotatercept

for
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Location: Durham NC
Sponsor: Bastiaan Driehuys

Sex: All

Age: 18 - 70+

Code: NCT06351345

Phase2, Recruiting