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Paid Clinical Trials Durham

Discover 1,621 paid clinical trials in Durham, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

for
Renal Cell Carcinoma (RCC),
Location: Durham NC, Charlottesville VA, Myrtle Beach SC,
Sponsor: Exelixis

Sex: All

Age: 18+

Code: NCT05176483

Phase1, Recruiting

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Durham NC, Winston-Salem NC, Greenville NC,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06672146

Phase2, Recruiting

Duke Customized Aortic Aneurysm Repair With Endovascular Stent-grafts - Duke CARES Trial

for
Aortic Disorders
Location: Durham NC
Sponsor: Chandler Long, MD

Sex: All

Age: 18+

Code: NCT07064460

Recruiting

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

for
Relapsed/Refractory Primary Central Nervous System Lymphoma
Location: Durham NC, Washington D.C. DC, Baltimore MD,
Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All

Age: 18+

Code: NCT07104032

Phase3, Recruiting

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

for
Muscle Invasive Bladder Urothelial Carcinoma,
Location: Durham NC, Chapel Hill NC, Midlothian VA, Richmond VA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07097142

Phase3, Recruiting

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Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

for
Advanced Hepatocellular Carcinoma,
Location: Durham NC, Raleigh NC, Fairfax VA, Falls Church VA,
Sponsor: NRG Oncology

Sex: All

Age: 18+

Code: NCT07166406

Phase3, Recruiting

Enhancing Heart Allograft Function With the OCS Heart System Trial

for
Heart Transplant
Location: Durham NC, New York NY, Valhalla NY, Tampa FL,
Sponsor: TransMedics

Sex: All

Age: 18+

Code: NCT07145515

Recruiting

Prescription of Letrozole for Uterine Myoma

for
Leiomyoma, Uterine, Leiomyoma, Fibroid, Fibroid Uterus
Location: Durham NC, Jackson MS, Rochester MN, Los Angeles CA,
Sponsor: University of California, San Francisco

Sex: Female

Age: 21 - 53

Code: NCT06143631

Recruiting

A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

for
Idiopathic Pulmonary Fibrosis
Location: Durham NC, Gainesville FL, Columbia MO, Iowa City IA
Sponsor: Boehringer Ingelheim

Sex: All

Age: 40+

Code: NCT07036523

Phase2, Recruiting

Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

for
BRAF V600 Mutation, Low-grade Glioma, Low Grade Glioma of Brain,
Location: Durham NC, Washington D.C. DC, Baltimore MD,
Sponsor: University of California, San Francisco

Sex: All

Age: 1 - 25

Code: NCT07110246

Phase2, Recruiting

A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for
Heart, Heart Failure With Preserved Ejection Fraction (HFPEF)
Location: Durham NC, Winston-Salem NC, Brick NJ, Jacksonville FL,
Sponsor: Vasa Therapeutics

Sex: All

Age: 50+

Code: NCT07219511

Phase1, Recruiting

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for
Heart Failure - NYHA II - IV
Location: Durham NC, Charlotte NC, Washington D.C. DC,
Sponsor: Boston Scientific Corporation

Sex: All

Age: 18+

Code: NCT07069738

Recruiting

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

for
Diffuse Midline Glioma, H3 K27-Altered,
Location: Durham NC, Washington D.C. DC, Baltimore MD,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 21

Code: NCT04870944

Phase1, Phase2, Recruiting

TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Location: Durham NC, Myrtle Beach SC, Charleston SC,
Sponsor: Novartis Pharmaceuticals

Sex: Male

Age: 18+

Code: NCT07190300

Phase1, Phase2, Recruiting

A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: Durham NC, Cincinnati OH, Cleveland OH, New York NY,
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All

Age: 18+

Code: NCT06859762

Phase1, Recruiting

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

for
Locally Advanced Adrenal Cortical Carcinoma,
Location: Durham NC, Cary NC, Raleigh NC, Richmond VA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 12+

Code: NCT06900595

Phase2, Recruiting

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for
Ovarian Neoplasms, Breast Neoplasms,
Location: Durham NC, Glen Burnie MD, Philadelphia PA, New York NY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07213791

Phase1, Recruiting

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

for
Castration-Sensitive Prostate Carcinoma,
Location: Durham NC, Pinehurst NC, Richmond VA, Tappahannock VA,
Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male

Age: 18+

Code: NCT06931340

Phase3, Recruiting

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

for
Acute Myeloid Leukemia (AML)
Location: Durham NC, Chapel Hill NC, Charlottesville VA,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT07007312

Phase3, Recruiting

An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)

for
Progressive Metastatic Castrate Resistant Prostate Cancer
Location: Durham NC, Atlanta GA, Cleveland OH, Denver CO,
Sponsor: Novartis Pharmaceuticals

Sex: Male

Age: 18+

Code: NCT07206056

Phase1, Phase2, Recruiting