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Paid Clinical Trials Columbus

Discover 1,289 paid clinical trials in Columbus, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

for
Ovarian Cancer, Fallopian Tube Cancer,
Location: Columbus OH, Cincinnati OH, Fort Wayne IN,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT06824467

Phase3, Recruiting

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

for
Limited Stage Small Cell Lung Cancer
Location: Columbus OH, Cincinnati OH, Lexington KY,
Sponsor: SCRI Development Innovations, LLC

Sex: All

Age: 18+

Code: NCT06773910

Phase2, Recruiting

A Long-term Extension Study of PCI-32765 (Ibrutinib)

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma,
Location: Columbus OH, Sioux Falls SD, Orange CA, Eugene OR
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT01804686

Phase3, Recruiting

CAR-T Long Term Follow Up (LTFU) Study

for
Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program,
Location: Columbus OH, Cincinnati OH, Ann Arbor MI, Detroit MI,
Sponsor: Novartis Pharmaceuticals

Sex: All

Age: 0 - 70+

Code: NCT02445222

Phase3, Recruiting

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

for
Metastatic Breast Cancer
Location: Columbus OH, Louisville KY, Grand Rapids MI, Toronto,
Sponsor: LeonaBio

Sex: All

Age: 18+

Code: NCT05696626

Phase3, Recruiting

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A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

for
Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD),
Location: Columbus OH, Cleveland OH, Chicago IL, Maywood IL,
Sponsor: Pierre Fabre Medicament

Sex: All

Age: 0+

Code: NCT03394365

Phase3, Recruiting

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Columbus OH, Cincinnati OH, Louisville KY, Chicago IL,
Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All

Age: 18+

Code: NCT06297226

Phase2, Recruiting

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for
Multiple Myeloma
Location: Columbus OH, Cincinnati OH, Cleveland OH, Ann Arbor MI,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT05552222

Phase3, Recruiting

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

for
Thrombocythemia, Essential, Primary Myelofibrosis,
Location: Columbus OH, Ann Arbor MI, Pittsburgh PA, Durham NC
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06351631

Phase3, Recruiting

Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

for
Acute Lymphocytic Leukemia
Location: Columbus OH, Cleveland OH, Boston MA, Omaha NE
Sponsor: Leland Metheny

Sex: All

Age: 16 - 70+

Code: NCT03104491

Phase1, Phase2, Recruiting

A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)

for
Sarcoma,Soft Tissue
Location: Columbus OH, Farmington Hills MI, Toronto, Durham NC,
Sponsor: Intensity Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06263231

Phase3, Recruiting

Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma

for
Retroperitoneal Liposarcoma
Location: Columbus OH, Toronto, Atlanta GA, Houston TX
Sponsor: Australia and New Zealand Sarcoma Association

Sex: All

Age: 18+

Code: NCT07377747

Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

for
Untreated, Unresectable, or Metastatic Colorectal Cancer
Location: Columbus OH, Silver Spring MD, Nashville TN,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07221357

Phase2, Phase3, Recruiting

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

for
Ovarian Neoplasms, Fallopian Tube Neoplasms,
Location: Hilliard OH, Columbus OH, Centerville OH, Cincinnati OH,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT07213804

Phase3, Recruiting

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

for
Cervical Cancer
Location: Columbus OH, London, Charlottesville VA, Knoxville TN,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT07216703

Phase3, Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

for
Non-Small Cell Lung Cancer
Location: Columbus OH, Cleveland OH, Pittsburgh PA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07100080

Phase2, Phase3, Recruiting

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

for
Relapsed Acute Myeloid Leukemia (AML),
Location: Columbus OH, Nashville TN, Chapel Hill NC,
Sponsor: Auron Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06846606

Phase1, Recruiting

Ivosidenib as Post-HSCT Maintenance for AML

for
IDH1 Mutation, Acute Myeloid Leukemia (AML),
Location: Columbus OH, Milwaukee WI, Atlanta GA, Boston MA,
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT06707493

Phase2, Recruiting

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

for
Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Location: Columbus OH, Lexington KY, Richmond VA, Hawthorne NY,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18+

Code: NCT07063745

Phase2, Phase3, Recruiting

Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

for
Multiple Myeloma, Newly Diagnosed, Multiple Myeloma (MM)
Location: Columbus OH, Nashville TN, Milwaukee WI, Chapel Hill NC,
Sponsor: SCRI Development Innovations, LLC

Sex: All

Age: 19+

Code: NCT06974786

Phase2, Recruiting