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Paid Clinical Trials Columbus

Discover 1,289 paid clinical trials in Columbus, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

for
Malignant Neoplasm
Location: Columbus OH, Toronto, Hackensack NJ, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06979596

Phase2, Recruiting

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

for
Endometrial Cancer
Location: Columbus OH, Centerville OH, Kettering OH,
Sponsor: Merck Sharp & Dohme LLC

Sex: Female

Age: 18+

Code: NCT06952504

Phase3, Recruiting

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

for
Upper Urinary Tract Urothelial Carcinoma, Urothelial Carcinoma
Location: Columbus OH, Cincinnati OH, Charlottesville VA,
Sponsor: UroGen Pharma Ltd.

Sex: All

Age: 18+

Code: NCT06774131

Phase3, Recruiting

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

for
Metastatic Head-and-neck Squamous-cell Carcinoma,
Location: Columbus OH, Pittsburgh PA, Chicago IL, Toronto,
Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT06064877

Phase3, Recruiting

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

for
Relapsed/Refractory Multiple Myeloma
Location: Columbus OH, Chicago IL, Toronto, Milwaukee WI,
Sponsor: BeOne Medicines

Sex: All

Age: 18+

Code: NCT04973605

Phase1, Phase2, Recruiting

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Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours

for
Germ Cell Tumor
Location: Columbus OH, Oak Lawn IL, Chicago IL, Park Ridge IL,
Sponsor: University of Sydney

Sex: All

Age: 11 - 50

Code: NCT02582697

Phase3, Recruiting

A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment

for
Hepatotoxicity, Tenosynovial Giant Cell Tumor
Location: Columbus OH, Boston MA, Santa Monica CA
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT04635111

Recruiting

A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Participants With Multiple Myeloma That is Resistant to Current Standard of Care Treatments

for
Multiple Myeloma
Location: Columbus OH, Detroit MI, Indianapolis IN,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT05137054

Phase1, Recruiting

Study of APVO436 in Patients With AML or MDS

for
AML, MDS
Location: Columbus OH, Greenville SC, Westwood KS, Gainesville FL,
Sponsor: Aptevo Research and Development LLC

Sex: All

Age: 18+

Code: NCT03647800

Phase1, Recruiting

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

for
Head and Neck Squamous Cell Carcinoma (HNSCC),
Location: Columbus OH, Grand Rapids MI, Houston TX,
Sponsor: Tanabe Pharma America, Inc.

Sex: All

Age: 18+

Code: NCT06943521

Phase1, Phase2, Recruiting

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
Location: Columbus OH, Cincinnati OH, Fort Wayne IN, Lexington KY,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18+

Code: NCT06119581

Phase3, Recruiting

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for
Neoplasms
Location: Columbus OH, Cincinnati OH, Cleveland OH, Lexington KY,
Sponsor: Celgene

Sex: All

Age: 0+

Code: NCT03435796

Phase2, Phase3, Recruiting

A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors

for
Metastatic Castration-Resistant Prostate Cancer (mCRPC),
Location: Columbus OH, Morgantown WV, Detroit MI,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT03972657

Phase1, Phase2, Recruiting

A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Columbus OH, Detroit MI, Toronto, Fairfax VA,
Sponsor: Nuvalent Inc.

Sex: All

Age: 18+

Code: NCT06521554

Phase1, Recruiting

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

for
Locally Advanced Solid Tumor, Metastatic Solid Tumor
Location: Columbus OH, Detroit MI, Chicago IL, Toronto,
Sponsor: Nuvalent Inc.

Sex: All

Age: 12+

Code: NCT05384626

Phase1, Phase2, Recruiting

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

for
Non-small Cell Lung Cancer
Location: Columbus OH, Edgewood KY, Huntington WV, Cleveland OH,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06077760

Phase3, Recruiting

Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for
Low-grade NMIBC, FGFR Gene Amplification, FGFR Gene Alterations,
Location: Columbus OH, Greenwood IN, Jeffersonville IN,
Sponsor: Tyra Biosciences, Inc

Sex: All

Age: 18+

Code: NCT06995677

Phase2, Recruiting
New

Serum Inflammatory Protein Concentration During Dental Treatment

for
Periodontal Disease, Periodontal Surgery
Location: Columbus OH
Sponsor: Ohio State University

Sex: All

Age: 21 - 70+

Code: NCT07468929

Recruiting

Acellular Collagen Matrix as a Tool to Obtain Wound Closure Following a Guided Bone Regeneration Procedure

for
Bone Graft
Location: Columbus OH
Sponsor: Ohio State University

Sex: All

Age: 21 - 70+

Code: NCT06871735

Recruiting

Taking Measurements of a Gum Graft Site as it Heals

for
Gingival Recession
Location: Columbus OH
Sponsor: Ohio State University

Sex: All

Age: 18 - 50

Code: NCT07386457

Recruiting