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Paid Clinical Trials Columbus

Discover 1,289 paid clinical trials in Columbus, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

for
Advanced Unresectable Solid Tumor, Metastatic Solid Tumor
Location: Columbus OH, Detroit MI, Baltimore MD, Madison WI,
Sponsor: TopAlliance Biosciences

Sex: All

Age: 18+

Code: NCT04137900

Phase1, Recruiting

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

for
Carcinoma, Non-Small-Cell Lung
Location: Columbus OH, Philadelphia PA, Lebanon NH,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT04165070

Phase1, Phase2, Recruiting

Third Party Viral Specific T-cells (VSTs)

for
Viral Infection, Viral Reactivation,
Location: Columbus OH, Cincinnati OH, Akron OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 0+

Code: NCT02532452

Phase2, Recruiting

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for
Epithelial Ovarian Cancer, Primary Peritoneal,
Location: Columbus OH, Chicago IL, Toronto, Annapolis MD,
Sponsor: TORL Biotherapeutics, LLC

Sex: Female

Age: 18+

Code: NCT06690775

Phase2, Recruiting

Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling

for
HER2-negative Breast Cancer
Location: Columbus OH, Delaware OH, Newark OH, Mount Vernon OH,
Sponsor: NSABP Foundation Inc

Sex: Female

Age: 18+

Code: NCT03412643

Phase2, Recruiting

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for
Acute Myeloid Leukemia, Mixed Lineage Leukemia Gene Mutation,
Location: Columbus OH, Cleveland OH, Louisville KY, Ann Arbor MI,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT05735184

Phase1, Recruiting

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for
HIV Infection, Tobacco-Related Carcinoma
Location: Columbus OH, Washington D.C. DC, St Louis MO,
Sponsor: AIDS Malignancy Consortium

Sex: All

Age: 45 - 70+

Code: NCT04949464

Recruiting

A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

for
Advanced Biliary Tract Cancer, Biliary Tract Cancer (BTC)
Location: Columbus OH, Cleveland OH, Detroit MI, Louisville KY,
Sponsor: J-Pharma Co., Ltd.

Sex: All

Age: 18+

Code: NCT07265674

Phase3, Recruiting

Ziftomenib Maintenance Post Allo-HCT

for
Acute Myeloid Leukemia, Acute Myeloid Leukemia in Remission,
Location: Columbus OH, Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18+

Code: NCT06440135

Phase1, Recruiting

Computer-Based Continuing Education for Doctors in Examination and Counseling of Patients on Skin Cancer or Weight Control

for
Melanoma (Skin), Non-melanomatous Skin Cancer
Location: Columbus OH, Philadelphia PA, Providence RI, Wichita KS,
Sponsor: Rhode Island Hospital

Sex: All

Age: 18+

Code: NCT00295906

Recruiting

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

for
Advanced Solid Tumor
Location: Columbus OH, Pittsburgh PA, Toronto, Montreal,
Sponsor: Senhwa Biosciences, Inc.

Sex: All

Age: 18+

Code: NCT04890613

Phase1, Recruiting

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

for
Relapsed/Refractory B-cell Malignancies
Location: Columbus OH, Cleveland OH, Chapel Hill NC, Sarasota FL,
Sponsor: Accutar Biotechnology Inc

Sex: All

Age: 18+

Code: NCT05780034

Phase1, Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

for
Mature B-Cell Neoplasm, Non Hodgkin Lymphoma, DLBCL,
Location: Columbus OH, Canton OH, Buffalo NY, Milwaukee WI,
Sponsor: Schrödinger, Inc.

Sex: All

Age: 18+

Code: NCT05544019

Phase1, Recruiting

Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma

for
Multiple Myeloma
Location: Columbus OH, Louisville KY, Atlanta GA, New York NY,
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT03761108

Phase1, Phase2, Recruiting

A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

for
Non-muscle Invasive Bladder Cancer With Carcinoma in Situ
Location: Columbus OH, Cincinnati OH, Pittsburgh PA,
Sponsor: Ferring Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06545955

Phase3, Recruiting

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

for
Myelodysplastic Syndromes, Acute Myeloid Leukemia,
Location: Columbus OH, Buffalo NY, Toronto, Nashville TN,
Sponsor: Taiho Oncology, Inc.

Sex: All

Age: 18+

Code: NCT04256317

Phase2, Phase3, Recruiting

A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for
Metastatic Castration-resistant Prostate Cancer
Location: Columbus OH, Louisville KY, Buffalo NY, Milwaukee WI,
Sponsor: Regeneron Pharmaceuticals

Sex: Male

Age: 18+

Code: NCT05125016

Phase1, Phase2, Recruiting

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

for
Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute,
Location: Columbus OH, Chicago IL, Buffalo NY, Nashville TN,
Sponsor: BlossomHill Therapeutics

Sex: All

Age: 18+

Code: NCT06501196

Phase1, Recruiting

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

for
High Grade Epithelial Ovarian Cancer,
Location: Columbus OH, Pittsburgh PA, Detroit MI, Grand Rapids MI,
Sponsor: Genmab

Sex: All

Age: 18+

Code: NCT05579366

Phase1, Phase2, Recruiting

Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma

for
Relapsed and/or Refractory B-cell Lymphoma
Location: Columbus OH, Shelbyville KY, Park Ridge IL,
Sponsor: Kite, A Gilead Company

Sex: All

Age: 18+

Code: NCT04989803

Phase1, Phase2, Recruiting