Discover 1,289 paid clinical trials in Columbus, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Columbus hosts a variety of active clinical studies, including for conditions such as diabetes, asthma, and cardiovascular diseases. The city's prominent healthcare institutions are recruiting participants, both as healthy volunteers seeking paid research opportunities and individuals in need of trials for specific conditions, offering access to new and innovative treatments and therapies.
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Results: 1,289
Active & Responsive
KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)
for
Carcinoma, Non-Small-Cell Lung
Location: Columbus OH, Philadelphia PA, Lebanon NH,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 18+
Code: NCT04165798
Recruiting
Active & Responsive
A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety
for
Depression, Anxiety, Major Depressive Disorder
Location: Columbus OH
Sponsor: Ohio State University
Sex: All
Age: 21 - 65
Code: NCT06820723
Phase2, Recruiting
Active & ResponsiveNew
Study to Refine the Effectiveness of New Generation Therapies for Suicide
for
Suicide Risk, Suicide Attempt, Treatment Response
Location: Columbus OH
Sponsor: Ohio State University
Sex: All
Age: 18+
Code: NCT07818889
Recruiting
Active & Responsive
Uncertainty and Firearms: Obtaining Secure Storage
for
Anxiety
Location: Columbus OH
Sponsor: Ohio State University
Sex: All
Age: 18+
Code: NCT05818696
Recruiting
Active & Responsive
Anxiety Skills Study
for
Anxiety, Anxiety Acute, Anxiety Chronic,
Location: Columbus OH
Sponsor: Ohio State University
Sex: All
Age: 18+
Code: NCT07774481
Recruiting
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Active & ResponsiveNew
A Study of V132 in Healthy Older Participants (V132-001)
for
Healthy
Location: Columbus OH, Springfield MO, Omaha NE, Lincoln NE,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 50 - 70+
Code: NCT07712575
Phase1, Recruiting
Active & Responsive
A Study to Evaluate Safety, Tolerability, and Immunogenicity of V350A and V350B in Healthy Participants (V350-001).
for
Healthy
Location: Columbus OH, Springfield MO, Kansas City MO, Omaha NE,
Sponsor: Merck Sharp & Dohme LLC
Sex: All
Age: 12 - 30
Code: NCT06655324
Phase1, Recruiting
Active & Responsive
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
for
Diabetes Mellitus, Type 2, Hypertension,
Location: Columbus OH, Cincinnati OH, Richmond IN, Westlake OH,
Sponsor: Boehringer Ingelheim
Sex: All
Age: 18+
Code: NCT07064473
Phase3, Recruiting
Active & Responsive
Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD
for
COPD, Chronic Obstructive Pulmonary Disease
Location: Columbus OH, Detroit MI, DuBois PA, Philadelphia PA,
Sponsor: Nuvaira, Inc.
Sex: All
Age: 40 - 70+
Code: NCT07051707
Recruiting
Active & Responsive
A Study of SGT-212 Gene Therapy in Friedreich's Ataxia
for
Friedreich's Ataxia (FA)
Location: Columbus OH, Philadelphia PA, Los Angeles CA
Sponsor: Solid Biosciences Inc.
Sex: All
Age: 18 - 40
Code: NCT07180355
Phase1, Recruiting
Active & Responsive
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
for
Alzheimer's Disease
Location: Columbus OH, Dayton OH, Chicago IL,
Sponsor: Bristol-Myers Squibb
Sex: All
Age: 60 - 70+
Code: NCT06976216
Phase3, Recruiting
Active & Responsive
A Frequency-Modulated Music Intervention to Enhance Cognitive Processing Therapy (CPT) for PTSD
for
PTSD - Post Traumatic Stress Disorder
Location: Columbus OH, Dayton OH
Sponsor: Ohio State University
Sex: All
Age: 18+
Code: NCT06925867
Recruiting
Active & Responsive
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Sex: All
Age: 55 - 70+
Code: NCT06585787
Phase3, Recruiting
Active & Responsive
Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency
for
Exocrine Pancreatic Insufficiency
Location: Columbus OH, Pittsburgh PA, Chicago IL, Los Angeles CA
Sponsor: Ohio State University
Sex: All
Age: 18+
Code: NCT06477159
Recruiting
Active & Responsive
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
Location: Columbus OH, St Louis MO, New York NY, Rochester MN,
Sponsor: A2 Biotherapeutics Inc.
Sex: All
Age: 18+
Code: NCT06682793
Phase1, Phase2, Recruiting
Active & Responsive
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
for
Geographic Atrophy, Macular Degeneration
Location: Columbus OH, Dayton OH, Grand Blanc MI, Erie PA,
Sponsor: Astellas Pharma Global Development, Inc.
Sex: All
Age: 0+
Code: NCT06779773
Recruiting
Active & Responsive
ASSESS ALL ALS Study
for
Amyotrophic Lateral Sclerosis
Location: Colombus OH, Ann Arbor MI, Detroit MI, Indianapolis IN,
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix
Sex: All
Age: 18+
Code: NCT06578195
Recruiting
Active & Responsive
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression