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Active & Responsive

Investigation of Psychedelic Effects in Psychoactive Substances

for
Psychedelic Effects in Healthy Volunteers
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 25 - 55

Code: NCT06772753

Phase 1, Recruiting
Active & Responsive

Effect of Cannabis on Cigarette Use Behavior

for
Cannabis Use, Tobacco Use, Cigarette Smoking
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 21+

Code: NCT06609083

Phase 1, Recruiting
Active & Responsive

Technology Assisted Motivational Interviewing

for
Smoking, Smoking Cessation
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT06713603

Recruiting
Active & Responsive

Building Connections

for
Cancer Colorectal, Cancer Cervix, Depression, Anxiety, Obesity
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT07091032

Recruiting
Active & Responsive

Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE)

for
Pain, Sleep, Anxiety, Depression, Epilepsy
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 19+

Code: NCT04526093

Recruiting

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Active & Responsive

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

for
Plasma Cell Myeloma
Location: Exeter NH, Westerly RI, Waterford CT, Guilford CT,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 0+

Code: NCT05561387

Phase 3, Recruiting
Active & Responsive

Concurrent TMS-fMRI

for
Healthy Control, Depression
Location: Iowa City IA
Sponsor: Jing Jiang

Sex: All

Age: 18 - 65

Code: NCT06633913

Recruiting
Active & Responsive

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

for
Amyotrophic Lateral Sclerosis, Movement Disorders,
Location: Boston MA, New York NY, Georgetown DC, Jacksonville FL,
Sponsor: Target ALS Foundation, Inc.

Sex: All

Age: 18+

Code: NCT05137665

Recruiting
Active & Responsive

Neurostimulation Versus Therapy for Problems With Emotions

for
Emotion Regulation, Mood Disorders, Stress Disorder,
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 55

Code: NCT05712057

Recruiting
Active & Responsive

Defining Neurobiological Links Between Substance Use and Mental Illness

for
Major Depressive Disorder, Substance Use Disorder,
Location: Baltimore MD
Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All

Age: 18 - 60

Code: NCT05538910

Recruiting
Active & Responsive

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

for
Asthma
Location: Boston MA, Quebec, New York NY, Saint-Laurent, Doral FL,
Sponsor: Eli Lilly and Company

Sex: All

Age: 18 - 70+

Code: NCT07219173

Phase 2, Recruiting
Active & Responsive

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

for
Mania, Bipolar Disorder
Location: Staten Island NY, Boynton Beach FL, Savannah GA,
Sponsor: Bristol-Myers Squibb

Sex: All

Age: 18 - 65

Code: NCT07140913

Phase 3, Recruiting
Active & Responsive

A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism

for
Myopia, Astigmatism
Location: Draper UT
Sponsor: Hoopes Vision

Sex: All

Age: 22 - 50

Code: NCT07201298

Recruiting
Active & Responsive

ADRC Clinical Cohort (Alzheimer's Disease)

for
Alzheimer Disease, Mild Cognitive Impairment, Dementia
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 25 - 70+

Code: NCT06703541

Recruiting
Active & Responsive

Oklahoma Study of Native American Pain Risk III: Stress and Resilience

for
Discrimination, Racial, Stress Physiology, Pain
Location: Tulsa OK
Sponsor: University of Oklahoma

Sex: All

Age: 18+

Code: NCT05723081

Recruiting
Active & Responsive

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

for
Neuropathic Pain
Location: Indianapolis IN
Sponsor: Indiana University

Sex: All

Age: 18 - 70+

Code: NCT06420141

Recruiting
Active & Responsive

Natural History of Depression, Bipolar Disorder and Suicide Risk

for
Behavioral Symptoms, Suicide, Self-Injurious Behavior,
Location: Bethesda MD
Sponsor: National Institute of Mental Health (NIMH)

Sex: All

Age: 18 - 70+

Code: NCT06462196

Recruiting
Active & Responsive

Blood Flow Restriction Training for People With Disabilities

for
Weakness, Muscle
Location: Milwaukee WI
Sponsor: Medical College of Wisconsin

Sex: All

Age: 18+

Code: NCT06441422

Recruiting
Active & Responsive

R61/33 - VR Study Phase 4

for
Attention Deficit Hyperactivity Disorder
Location: New Brunswick NJ, Baton Rouge LA
Sponsor: Rutgers, The State University of New Jersey

Sex: All

Age: 18 - 25

Code: NCT07169760

Recruiting
Active & Responsive

Open-Label Psilocybin Study in Transdiagnostic Population

for
Transdiagnostic, Depression - Major Depressive Disorder,
Location: New Haven CT
Sponsor: Yale University

Sex: All

Age: 18+

Code: NCT06442423

Phase 1, Recruiting