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Active & Responsive

Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation.

for
Overweight (BMI > 25), Obesity (BMI>30), Hs-CRP
Location: Chicago IL
Sponsor: Midwest Center for Metabolic and Cardiovascular Research

Sex: All

Age: 21 - 70+

Code: NCT07566325

Recruiting
Active & Responsive

Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease

for
Degenerative Disc Disease
Location: Philadelphia PA, Miami FL, Morgantown WV,
Sponsor: CGBio Inc.

Sex: All

Age: 21 - 70+

Code: NCT07017634

Phase 3, Recruiting
Active & Responsive

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

for
Moderate to Severe Chronic Obstructive Pulmonary Disease
Location: North Dartmouth MA, Fall River MA, Quebec, Flushing NY,
Sponsor: Pfizer

Sex: All

Age: 35 - 70+

Code: NCT07363694

Phase 2, Phase 3, Recruiting
Active & Responsive

A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System

for
Post Traumatic Arthritis, Osteoarthritis,
Location: Charleston SC, Louisville KY, South Bend IN,
Sponsor: Stryker Trauma and Extremities

Sex: All

Age: 21+

Code: NCT07118501

Recruiting
Active & Responsive

Home-Based tDCS for Depression in BPD

for
Major Depressive Disorder (MDD),
Location: Montreal
Sponsor: Ciusss de L'Est de l'Île de Montréal

Sex: All

Age: 18 - 65

Code: NCT06972368

Recruiting

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Active & Responsive

Effect of Mindfulness-based Neurofeedback for Adolescents With Elevated Repetitive Negative Thinking

for
Repetitive Negative Thinking, Neurofeedback
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 13 - 21

Code: NCT07055217

Recruiting
Active & Responsive

Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for
Diabetic Peripheral Neuropathic Pain
Location: Boston MA, Waltham MA, East Greenwich RI, New York NY,
Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All

Age: 18 - 70+

Code: NCT06628908

Phase 3, Recruiting
Active & Responsive

Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine

for
Major Depressive Disorder
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18 - 65

Code: NCT05327699

Early Phase 1, Recruiting
Active & Responsive

A Self-compassion Focused Intervention for Internalized Weight Bias and Weight Loss

for
Overweight and Obesity
Location: Greenville NC
Sponsor: East Carolina University

Sex: All

Age: 18+

Code: NCT05987306

Recruiting
Active & Responsive

Pistachio Snacking and Metabolic Flexibility

for
Overweight (BMI &gt; 25),
Location: Columbia SC
Sponsor: University of South Carolina

Sex: All

Age: 25 - 45

Code: NCT07340125

Recruiting
Active & Responsive

THC Titration of High-Potency Cannabis Concentrates

for
THC
Location: Toronto
Sponsor: Centre for Addiction and Mental Health

Sex: All

Age: 19 - 55

Code: NCT07105449

Recruiting
Active & Responsive

Fasted vs. Fed State Exercise

for
Obesity, Exercise, Weight Loss
Location: Fort Smith AR
Sponsor: Arkansas Colleges of Health Education

Sex: All

Age: 18 - 59

Code: NCT07487090

Phase 2, Recruiting
Active & Responsive

Observing Metabolism of EPA With Consideration of Genetics And Sex

for
Healthy, Omega 3, Metabolism, Lipids
Location: Toronto
Sponsor: University of Toronto

Sex: All

Age: 18 - 35

Code: NCT06975241

Recruiting
Active & Responsive

A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients

for
Breast Cancer Screening, Artificial Intelligence (AI)
Location: Boston MA, Miami FL, Madison WI, Seattle WA,
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06934239

Phase 4, Recruiting
Active & Responsive

Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression

for
Depression Disorders, Depression - Major Depressive Disorder,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 65

Code: NCT07082998

Recruiting
Active & Responsive

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

for
Long COVID, Sars-CoV-2 Infection, Coronavirus Infections,
Location: Boston MA, New Haven CT, Brooklyn NY, Morgantown WV,
Sponsor: Wes Ely

Sex: All

Age: 18+

Code: NCT06631287

Phase 3, Recruiting
Active & Responsive

Healthy Volunteers Study

for
Ovarian Cancer, Genetic Predisposition to Disease
Location: Philadelphia PA
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female

Age: 30 - 50

Code: NCT06962059

Recruiting
Active & Responsive

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for
PIK3CA Mutation, Solid Tumor, Adult,
Location: Boston MA, New Haven CT, New York NY, New Brunswick NJ,
Sponsor: Relay Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT05216432

Phase 1, Recruiting
Active & Responsive

Biomarkers of Depression and Treatment Response

for
Depressive Disorder, Major
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18 - 70

Code: NCT04581902

Recruiting
Active & Responsive

Influenza Human Challenge Model

for
Influenza
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18 - 49

Code: NCT05332899

Phase 1, Recruiting