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Vaccines Clinical Trials

Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.

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Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

for
HR+/HER2-negative Breast Cancer, Metastatic Breast Cancer
Location: Hershey PA, Miami FL, Cleveland OH, Ypsilanti MI,
Sponsor: SynDevRx, Inc.

Sex: All

Age: 18+

Code: NCT05455619

Phase1, Phase2, Recruiting

Influenza & COVID-19 Obstetric and Perinatal Epidemiology Study in India

for
Influenza, COVID-19, SARS-COV-2 Infection,
Location: Boston MA
Sponsor: Boston University

Sex: Female

Age: 18 - 50

Code: NCT06168019

Recruiting

National Liver Cancer Screening Trial

for
Carcinoma, Hepatocellular, Liver Cancer, Liver Cirrhosis,
Location: Boston MA, Manhasset NY, Philadelphia PA, Richmond VA,
Sponsor: University of Texas Southwestern Medical Center

Sex: All

Age: 18 - 70+

Code: NCT06084234

Recruiting

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06636734

Phase2, Recruiting

A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid Tumors

for
Triple Negative Locally Advanced Non-resectable Breast Cancer,
Location: Boston MA, Toronto, Columbus OH, Nashville TN,
Sponsor: Marengo Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06827613

Phase1, Phase2, Recruiting

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A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for
Advanced Solid Tumors, HER2 Mutation
Location: Boston MA, Toronto, Fort Myers FL, Cleveland OH,
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06760819

Phase2, Recruiting

A Study of D3L-001 as Monotherapy in Subjects With HER2-Positive Advanced Solid Tumors

for
HER-2 Positive Advanced Solid Tumors
Location: New York NY
Sponsor: D3 Bio (Wuxi) Co., Ltd

Sex: All

Age: 18+

Code: NCT05957536

Phase1, Recruiting

Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer

for
Breast Adenocarcinoma, HER2-Positive Breast Carcinoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: Female

Age: 18+

Code: NCT04517838

Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for
Breast Neoplasms, Breast Cancer, Breast Tumors, Angiosarcoma,
Location: New Haven CT, The Bronx NY, New York NY,
Sponsor: QuantumLeap Healthcare Collaborative

Sex: All

Age: 18+

Code: NCT01042379

Phase2, Recruiting

HPV Self-Collection Program

for
HPV
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: Female

Age: 25 - 65

Code: NCT06674681

Recruiting

Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer

for
Breast Cancer, Locally Advanced Breast Cancer,
Location: Stony Brook NY
Sponsor: Alison Stopeck

Sex: Female

Age: 18+

Code: NCT06220214

Early_phase1, Recruiting

Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer.

for
Vulvar Cancer, Cervical Cancer, Vulvar Dysplasia,
Location: Toronto
Sponsor: Dr. Danielle Vicus

Sex: Female

Age: 40+

Code: NCT03061435

Recruiting

Baloxavir and Oseltamivir for the Treatment of Severe Influenza Infection in Immunocompromised Patients

for
Hematopoietic and Lymphoid Cell Neoplasm, Influenza
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12+

Code: NCT04712539

Phase2, Recruiting

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

for
Adenocarcinoma of the Rectum,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05672524

Phase2, Recruiting

Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer

for
ER-Positive Breast Cancer, HER2-negative Breast Cancer
Location: Houston TX
Sponsor: The Methodist Hospital Research Institute

Sex: All

Age: 18+

Code: NCT05305924

Phase2, Recruiting

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

for
HPV-Associated Oropharyngeal Squamous Cell Carcinoma,
Location: Boston MA
Sponsor: Jonathan Schoenfeld, MD, MPH

Sex: All

Age: 22+

Code: NCT04900623

Phase2, Recruiting

HepB mAb19 in Individuals With Chronic Hepatitis B Infection

for
Hepatitis b Virus, Hepatitis B
Location: New York NY
Sponsor: Rockefeller University

Sex: All

Age: 18 - 70

Code: NCT05856890

Phase1, Recruiting

Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast Cancer

for
HER2-positive Breast Cancer
Location: Lee's Summit MO, Kansas City MO, Kansas City KS,
Sponsor: Qamar Khan

Sex: Female

Age: 18+

Code: NCT03238495

Phase2, Recruiting

COVID-19 Booster and IIV Schedule in Immunocompromised Hosts

for
COVID 19, Influenza, Rheumatoid Arthritis (RA),
Location: Montreal
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All

Age: 18+

Code: NCT06599658

Phase2, Recruiting

Screening for LID Clinical Studies Unit Healthy Volunteer Protocols

for
Zika, Influenza
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 18 - 65

Code: NCT01386424

Recruiting

What are vaccine clinical trials?

Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.

Importance of clinical trials for vaccines

Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.

Types of interventions studied in vaccine clinical trials

Eligibility and participation in vaccine clinical trials

How to enroll in a vaccine clinical trial