Background illustration for clinical trials search

ALS Clinical Trials

Browse 127 ALS clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

Filter
1
Active & Responsive

Evaluating the Safety and Tolerability of Orally Administered DF-003 in ROSAH Syndrome Patients

for
ROSAH
Location: Durham NC, Salt Lake City UT
Sponsor: Shanghai Yao Yuan Biotechnology Ltd. (also known as Drug Farm)

Sex: All

Age: 18 - 65

Code: NCT06395285

Phase1, Recruiting
New

Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body Myositis

for
IBM, Inclusion Body Myositis, Myopathy, Myositis,
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT07823101

Recruiting

Neurologic Stem Cell Treatment Study

for
Neurologic Disorders, Nervous System Diseases,
Location: Westport CT, Coral Springs FL
Sponsor: MD Stem Cells

Sex: All

Age: 18+

Code: NCT02795052

Recruiting

UPenn Observational Research Repository on Neurodegenerative Disease

for
Frontotemporal Degeneration(FTD),
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT04715399

Recruiting

NYSCF Scientific Discovery Biobank

for
ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease,
Location: New York NY
Sponsor: New York Stem Cell Foundation Research Institute

Sex: All

Age: 0+

Code: NCT06203106

Recruiting

Interested in new trials?

Get alerts for new trials in your area by subscribing now

Subscriber Image

Examining Interactions Between PALS and Caregivers

for
Amyotrophic Lateral Sclerosis (ALS)
Location: University Park PA
Sponsor: Penn State University

Sex: All

Age: 18 - 70+

Code: NCT06819124

Recruiting

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

for
Brainstem Stroke, ALS, Tetraplegia, Spinal Cord Injuries,
Location: Boston MA
Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All

Age: 18 - 70+

Code: NCT06511934

Recruiting

ECoG BMI for Motor and Speech Control

for
ALS, SCI - Spinal Cord Injury, Stroke, Multiple Sclerosis,
Location: San Francisco CA
Sponsor: Karunesh Ganguly

Sex: All

Age: 21+

Code: NCT03698149

Recruiting

Virtual Reality as an Adjunct to Management of Pain and Anxiety in Palliative Care

for
Cancer, Heart Failure, Copd, ALS
Location: Winnipeg
Sponsor: Riverview Health Centre

Sex: All

Age: 0+

Code: NCT04138095

Recruiting

Combined Respiratory Training in Persons With ALS

for
ALS, Respiratory Insufficiency, Dysphagia
Location: Fort Lauderdale FL
Sponsor: Nova Southeastern University

Sex: All

Age: 18 - 70+

Code: NCT05913882

Recruiting

A Clinical Trial of Pimozide in Patients With Amyotrophic Lateral Sclerosis (ALS)

for
ALS, Amyotrophic Lateral Sclerosis
Location: Fredericton, Greenfield Park, Montreal, Ottawa, Toronto,
Sponsor: University of Calgary

Sex: All

Age: 18+

Code: NCT03272503

Phase2, Recruiting

Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients

for
ALSFTD, ALS (Amyotrophic Lateral Sclerosis),
Location: Fredericton, Montreal, Saskatoon
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All

Age: 18+

Code: NCT06051123

Recruiting

Controlling Amyotrophic Lateral Sclerosis Motor Neuron Excitability Study

for
ALS - Amyotrophic Lateral Sclerosis
Location: Boston MA
Sponsor: PathMaker Neurosystems Inc.

Sex: All

Age: 18 - 70+

Code: NCT06649955

Recruiting

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

for
ALS
Location: Boston MA, Montreal, Philadelphia PA,
Sponsor: Amylyx Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT06665165

Phase1, Recruiting

Amyotrophic Lateral Sclerosis (ALS) Families Project

for
ALS
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 18 - 70+

Code: NCT03865420

Recruiting

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

for
Parkinson's Disease, Dementia, Alzheimer's Disease, ALS,
Location: Bethesda MD
Sponsor: National Institute of Mental Health (NIMH)

Sex: All

Age: 18 - 70+

Code: NCT04396873

Phase1, Recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

for
Amyotrophic Lateral Sclerosis (ALS),
Location: Montreal, Toronto, London, Edmonton
Sponsor: Regeneron Pharmaceuticals

Sex: All

Age: 18+

Code: NCT06351592

Phase1, Phase2, Recruiting

Tofersen in Non-SOD1 ALS

for
ALS (Amyotrophic Lateral Sclerosis)
Location: Boston MA, Atlanta GA, St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT07294144

Phase2, Recruiting

Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

for
Amyotrophic Lateral Sclerosis (ALS)
Location: Boston MA, New Britain CT, Richmond VA,
Sponsor: Zydus Therapeutics Inc.

Sex: All

Age: 18+

Code: NCT07023835

Phase2, Recruiting

A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

for
Amyotrophic Lateral Sclerosis (ALS),
Location: Philadelphia PA, Philadelphi PA, Hershey PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT07071935

Phase2, Recruiting

What are ALS clinical trials?

Amyotrophic Lateral Sclerosis (ALS) clinical trials are research studies conducted to explore and evaluate new treatments, therapies, and diagnostic tools for ALS, commonly known as Lou Gehrig’s disease. These trials are crucial in the search for effective ways to slow the progression of the disease, manage symptoms, and ultimately find a cure for ALS.

The importance of clinical trials in ALS research

Clinical trials are essential in ALS research as they are the primary method for testing new treatments and interventions. They help in understanding the effectiveness and safety of these treatments in humans. Through these trials, researchers can uncover new insights into the disease, leading to improved care, symptom management, and potentially life-extending therapies for those affected by ALS.

Types of ALS clinical trials

Innovations in ALS treatment through clinical trials

Who can participate in ALS clinical trials?

How to enroll in an ALS clinical trial