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ALS Clinical Trials

Browse 127 ALS clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Phase 2/3 Study on the Efficacy and Safety of Mangaciclanol for Contrast-Enhanced MRI of CNS or Body in Adult Patients

for
Known or Highly Suspected Central Nervous System (CNS) Lesion,
Location: Rochester MN, The Woodlands TX
Sponsor: GE Healthcare

Sex: All

Age: 18+

Code: NCT07472491

Phase2, Phase3, Recruiting

Systemic Hypothermia in Acute Cervical Spinal Cord Injury

for
Spinal Cord Injury, Acute
Location: Philadelphia PA, Baltimore MD, Miami FL, Columbia SC,
Sponsor: University of Miami

Sex: All

Age: 18 - 70

Code: NCT02991690

Recruiting

ACDF Using Structural Allograft vs. Tritanium C

for
Degenerative Disc Disease
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All

Age: 18 - 70+

Code: NCT04388332

Recruiting

Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer

for
Malignant Pleural Effusion, Malignant Ascites
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All

Age: 18 - 70+

Code: NCT06016179

Phase1, Recruiting

Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer

for
Cancer, Breast Cancer
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female

Age: 20 - 70+

Code: NCT06858449

Recruiting

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EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

for
Cancer
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All

Age: 20 - 70+

Code: NCT06083324

Recruiting

Effect of Hindmilk on Growth Velocity of Very Preterm Infants

for
Weight Gain
Location: Calgary
Sponsor: Belal Alshaikh

Sex: All

Age: 0+

Code: NCT03637413

Recruiting

EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer

for
Breast Cancer, Breast Carcinoma in Situ, Breast Cancer Female
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female

Age: 20 - 70+

Code: NCT06115486

Recruiting

Impact of Tamsulosin on Post-Operative Urinary Retention Following Pelvic Reconstructive Surgery

for
Urinary Retention Postoperative
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female

Age: 18+

Code: NCT04597372

Phase2, Recruiting

Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors

for
Malignant Pleural Effusion, Malignant Mesothelioma,
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All

Age: 18 - 70+

Code: NCT07443020

Phase1, Recruiting

EXERT-BC Cardio: Cardio or Conditioning Training With Breast Cancer

for
Cancer, Breast Cancer
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female

Age: 20 - 70+

Code: NCT07739563

Recruiting

Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

for
Cancer, Breast Cancer
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female

Age: 20 - 70+

Code: NCT07023887

Recruiting

Intra-tumoral (IT) Injection of vvDD-hIL2-2-RG-1 for Metastatic Gastrointestinal and Peritoneal Tumors

for
Gastric Neoplasms, Esophageal Cancer, Liver Cancer,
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All

Age: 18 - 69

Code: NCT07001592

Phase1, Recruiting

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

for
Opioid-use Disorder
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All

Age: 22 - 65

Code: NCT04354077

Recruiting

Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery

for
Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer,
Location: Pittsburgh PA
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All

Age: 18 - 70+

Code: NCT06731998

Recruiting

Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])

for
Prostate Cancer
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: Male

Age: 18+

Code: NCT05038332

Phase2, Recruiting

Early Feasibility of the Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) Also Known as TriAlign™.

for
Chronic Symptomatic Functional Tricuspid Regurgitation,
Location: New York NY, Washington, D.C. DC, Charlottesville VA,
Sponsor: Mitralign, Inc.

Sex: All

Age: 18 - 70+

Code: NCT02574650

Recruiting

Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for
Ovarian Cancer, Fallopian Tube Cancer,
Location: Houston TX, Oklahoma City OK
Sponsor: Imunon

Sex: Female

Age: 18+

Code: NCT05739981

Phase1, Phase2, Recruiting

An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)

for
Guillain-Barre Syndrome
Location: Worcester MA, Jacksonville FL, Detroit MI, Rochester MN,
Sponsor: Annexon, Inc.

Sex: All

Age: 12 - 70+

Code: NCT07020819

Phase3, Recruiting

Pegtibatinase as a Treatment for Patients With Classical Homocystinuria (HCU) (Also Known as the COMPOSE Study)

for
Homocystinuria
Location: Morrisville NC
Sponsor: Travere Therapeutics, Inc.

Sex: All

Age: 5 - 65

Code: NCT03406611

Phase1, Phase2, Recruiting

What are ALS clinical trials?

Amyotrophic Lateral Sclerosis (ALS) clinical trials are research studies conducted to explore and evaluate new treatments, therapies, and diagnostic tools for ALS, commonly known as Lou Gehrig’s disease. These trials are crucial in the search for effective ways to slow the progression of the disease, manage symptoms, and ultimately find a cure for ALS.

The importance of clinical trials in ALS research

Clinical trials are essential in ALS research as they are the primary method for testing new treatments and interventions. They help in understanding the effectiveness and safety of these treatments in humans. Through these trials, researchers can uncover new insights into the disease, leading to improved care, symptom management, and potentially life-extending therapies for those affected by ALS.

Types of ALS clinical trials

Innovations in ALS treatment through clinical trials

Who can participate in ALS clinical trials?

How to enroll in an ALS clinical trial