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Esophageal Cancer Clinical Trials

Browse 222 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Active & Responsive

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Boston MA, Fairfax VA, Orlando FL, Cleveland OH,
Sponsor: Terremoto Biosciences Inc.

Sex: All

Age: 18+

Code: NCT07109726

Phase1, Phase2, Recruiting
Active & Responsive

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

for
Gastric Adenocarcinoma,
Location: New York NY, Durham NC, Winston-Salem NC, Chicago IL,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: All

Age: 18+

Code: NCT05365581

Phase1, Recruiting
New

Prehabilitation in High-risk Oncologic Surgery

for
Pancreatic Cancer, Colo-rectal Cancer, Gastric Cancer,
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT07638410

Recruiting
New

A Study of 2141-V11 in People With Esophageal, Gastric, or Gastroesophageal Junction Adenocarcinoma

for
Esophageal Cancer, Advanced Esophageal Cancer, Gastric Cancer,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT07818018

Phase1, Phase2, Recruiting
New

SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors

for
Selected Advanced Solid Tumors, Colorectal Cancer (CRC),
Location: Glen Burnie MD
Sponsor: SK Life Science, Inc.

Sex: All

Age: 18+

Code: NCT07812805

Phase1, Recruiting

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Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for
Non Small Cell Lung Cancer, Esophageal Cancer,
Location: Boston MA, New Haven CT, New York NY,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT05983432

Phase1, Recruiting

Tissue Collection Protocol for Gastroesophageal Cancers

for
Esophageal Cancer
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT02495337

Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for
Diffuse Astrocytoma, IDH-Mutant, Glioblastoma, IDH-wildtype,
Location: Boston MA, Boynton Beach FL, Nashville TN, Dallas TX,
Sponsor: Neonc Technologies, Inc.

Sex: All

Age: 18+

Code: NCT06047379

Phase1, Phase2, Recruiting

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

for
Esophageal Cancer, Gastric Adenocarcinoma, HER2 Gene Mutation
Location: Boston MA, Commack NY, Uniondale NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06123338

Phase2, Recruiting

18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer

for
Esophageal Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06414902

Phase1, Recruiting

Pulsed Low Dose Rate Radiation With Concurrent Chemotherapy for Non-Small Cell Lung Cancer and Esophageal Cancer

for
Lung Cancer, Esophageal Cancer
Location: Philadelphia PA
Sponsor: Fox Chase Cancer Center

Sex: All

Age: 18+

Code: NCT03094884

Phase1, Recruiting

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

for
Healthy Volunteer, Prostate Cancer, Head and Neck Cancer,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT04354064

Recruiting

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

for
Non-small Cell Lung Cancer, Esophageal Cancer, Gastric Cancer,
Location: Columbia MO
Sponsor: University of Missouri-Columbia

Sex: All

Age: 18+

Code: NCT02838836

Recruiting

Non-endoscopic Esophageal Sampling to Detect Barrett's Esophagus and Esophageal Cancer in Veterans

for
Barrett Esophagus, GERD, Obesity, Esophageal Cancer
Location: Cleveland OH
Sponsor: Cleveland VA Medical Research and Education Foundation

Sex: All

Age: 40 - 70+

Code: NCT05210049

Recruiting

64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

for
Metastatic Sarcoma, Esophageal Cancer, Gastric Cancer,
Location: Cincinnati OH, Grand Rapids MI, Duarte CA, Orange CA,
Sponsor: Lantheus Medical Imaging

Sex: All

Age: 15+

Code: NCT06298916

Phase1, Phase2, Recruiting

Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers

for
Esophageal Cancer, Head and Neck Cancer, Lung Cancer,
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 21 - 70+

Code: NCT00900419

Recruiting

Chemoradiotherapy for Advanced Esophageal Cancer

for
Esophageal Cancer
Location: Calgary
Sponsor: AHS Cancer Control Alberta

Sex: All

Age: 18+

Code: NCT02297217

Phase2, Recruiting

EsophaCap for the Detection of Early Esophageal Carcinoma

for
Barrett Esophagus, Esophageal Cancer, Gastric Cancer
Location: Baltimore MD
Sponsor: Johns Hopkins University

Sex: All

Age: 18+

Code: NCT04214119

Recruiting

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for
Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer,
Location: Miami FL, Florence SC, Charleston SC, Cleveland OH,
Sponsor: Adela, Inc

Sex: All

Age: 40+

Code: NCT05366881

Recruiting

Serial MRI Scans During Radiation Therapy

for
Glioblastoma, Esophageal Cancer, Radiotherapy,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT04188535

Recruiting