Browse 1,747 esophageal cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.
There are two main types of esophageal cancer, and in the United States the more common one is now adenocarcinoma, linked to long term acid reflux and a condition called Barrett's esophagus. Because the esophagus stretches easily, symptoms such as trouble swallowing often appear only after the cancer has grown. Outcomes improve most when cancer is found early and treated with combinations, and trials are testing immunotherapy, targeted drugs, and better ways to spot cancer in people with Barrett's esophagus before it develops.
Sponsor: Masonic Cancer Center, University of Minnesota
Sex: All
Age: 18+
Code: NCT07541573
Phase 1, Recruiting
Active & Responsive
Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors
for
Advanced Malignant Solid Neoplasm,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute
Sex: All
Age: 18+
Code: NCT06320405
Phase 1, Phase 2, Recruiting
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Active & Responsive
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
for
Breast Cancer, Endometrial Cancer, Ovarian Cancer,
Location: Boston MA, Fairfax VA, Orlando FL, Cleveland OH,
Sponsor: Terremoto Biosciences Inc.
Sex: All
Age: 18+
Code: NCT07109726
Phase 1, Phase 2, Recruiting
Active & Responsive
Met Non Small Cell Cancer Registry (MOMENT)
for
Cancer
Location: Quebec, Ottawa, Fort Lauderdale FL, Toronto,
Sponsor: EMD Serono Research & Development Institute, Inc.
Sex: All
Age: 0+
Code: NCT05376891
Recruiting
Active & Responsive
A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors
for
Solid Tumor
Location: New York NY, Philadelphia PA, Washington D.C. DC,
Sponsor: Biohaven Therapeutics Ltd.
Sex: All
Age: 18+
Code: NCT06384807
Phase 1, Phase 2, Recruiting
Active & Responsive
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
for
Cancer, PDAC - Pancreatic Ductal Adenocarcinoma,
Location: Boston MA, New York NY, Fairfax VA, Durham NC,
Sponsor: Alterome Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT06835569
Phase 1, Recruiting
Active & Responsive
F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors)
for
Oral Mucositis, Periodontal Diseases, Cancer
Location: Washington D.C. DC
Sponsor: Georgetown University
Sex: All
Age: 25 - 70+
Code: NCT06315855
Recruiting
Active & Responsive
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
Location: New York NY, Jacksonville FL, Tampa FL, Columbus OH,
Sponsor: A2 Biotherapeutics Inc.
Sex: All
Age: 18+
Code: NCT06682793
Phase 1, Phase 2, Recruiting
Active & Responsive
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
for
PIK3CA Mutation, Solid Tumor, Adult,
Location: Boston MA, New Haven CT, New York NY, New Brunswick NJ,
Sponsor: Relay Therapeutics, Inc.
Sex: All
Age: 18+
Code: NCT05216432
Phase 1, Recruiting
Active & Responsive
Decentralized Clinical Trial of Effectiveness of EnergyPoints App in Cancer Survivors
for
Cancer-related Problem/Condition, Fatigue in Cancer Survivors,
Location: New York NY
Sponsor: 5 Point App, Inc.
Sex: All
Age: 18+
Code: NCT06754722
Recruiting
Active & Responsive
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO