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Head & Neck Cancer Clinical Trials

Browse 313 head & neck cancer clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

for
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT05420948

Phase2, Recruiting

Response-Adaptive Treatment in Untreated Locoregional HPV-Negative Head and Neck Cancer

for
Head and Neck Cancer, HPV
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT07065630

Phase2, Recruiting

Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK)

for
Head and Neck Cancer
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT07101432

Phase1, Recruiting

Stereotactic Post-operative Radiotherapy for Intraparotid Metastatic Cutaneous Squamous Cell Carcinoma

for
Cutaneous, Head and Neck Cancer Squamous Cell Carcinoma
Location: London
Sponsor: David Palma

Sex: All

Age: 18+

Code: NCT07337161

Recruiting

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

for
Head and Neck Neoplasms, Carcinoma, Squamous Cell,
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 18+

Code: NCT06912087

Phase1, Recruiting

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Velopharyngeal Dysfunction in Head & Neck Cancer Patients, Pilot Study

for
Velopharyngeal Insufficiency, Head and Neck Cancer,
Location: Charlottesville VA
Sponsor: Vanessa Torrecillas

Sex: All

Age: 18+

Code: NCT07264036

Recruiting

Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema

for
Head and Neck Cancer, Lymphedema of the Head and Neck
Location: Philadelphia PA, Nashville TN
Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All

Age: 18+

Code: NCT06837480

Recruiting

Survivorship After HNC: A Randomized Controlled Trial Evaluating Patient Care and Adherence to Follow-up

for
Head and Neck Cancer, Survivorship
Location: London
Sponsor: Western University, Canada

Sex: All

Age: 18+

Code: NCT06127784

Recruiting

Apixaban or Enoxaparin After Head and Neck Cancer Surgery

for
Venous Thromboembolism, Head and Neck Cancer
Location: Syracuse NY
Sponsor: Kiranya Arnold

Sex: All

Age: 18 - 70+

Code: NCT07189897

Recruiting

Supporting Treatment Resilience With Optimized Nutrition and Guided Exercise in Head and Neck Cancer Patients Undergoing Chemoradiation

for
Head and Neck Cancer
Location: Reno NV
Sponsor: Renown Health

Sex: All

Age: 18+

Code: NCT07160296

Recruiting

Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

for
Head and Neck Cancer,
Location: Cincinnati OH
Sponsor: University of Cincinnati

Sex: All

Age: 18+

Code: NCT07213934

Phase1, Phase2, Recruiting

NLit and Outcomes in HNC Survivor-Caregiver Dyads

for
Head and Neck Cancer, Caregiver Burden,
Location: Kansas City KS
Sponsor: University of Kansas Medical Center

Sex: All

Age: 18+

Code: NCT07021885

Recruiting

Pembrolizumab Plus Ultrasound-Induced Microbubble Cavitation in Head and Neck Cancer

for
Head and Neck Cancer, Head and Neck Small Cell Carcinoma,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT07501650

Phase1, Recruiting

Impact of Photobiomodulation (PBM) on Biomarkers of Radiation Lymphedema and Fibrosis in Head and Neck Cancer Patients

for
Radiation Lymphedema, Radiation Fibrosis, Head and Neck Cancer
Location: New York NY
Sponsor: NYU Langone Health

Sex: All

Age: 18+

Code: NCT06708754

Recruiting

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

for
Neoplasms, Head and Neck
Location: Worcester MA, Farmington CT, New Haven CT, The Bronx NY,
Sponsor: GlaxoSmithKline

Sex: All

Age: 18+

Code: NCT06256588

Phase3, Recruiting

Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus

for
Head and Neck Cancer, Trismus
Location: Edmonton
Sponsor: University of Alberta

Sex: All

Age: 18+

Code: NCT06531083

Recruiting

Study of Non-invasive Acupuncture-like Transcutaneous Electrical Nerve Stimulation (Altens) to Help Alleviate Xerostomia After Radiation Therapy for Cancers of the Head and Neck

for
Head and Neck Cancer
Location: Rochester NY
Sponsor: University of Rochester

Sex: All

Age: 18+

Code: NCT04805528

Recruiting

Implementing the NYU Electronic Patient Visit Assessment (ePVA) for Head and Neck Cancer In Rural and Urban Populations

for
Head and Neck Cancer
Location: New York NY, Kansas City KS
Sponsor: The University of Texas Health Science Center, Houston

Sex: All

Age: 18+

Code: NCT06030011

Recruiting

Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy

for
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma,
Location: Durham NC, Charleston SC, St Louis MO, Houston TX
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT05793151

Recruiting

A Motion Exergaming Approach for Symptom Management: HNC

for
Head and Neck Cancer
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18+

Code: NCT04632654

Recruiting