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Leukemia Clinical Trials

Browse 1,314 Leukemia clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse

for
Acute Myeloid Leukemia, Acute Undifferentiated Leukemia,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT06928662

Phase1, Phase2, Recruiting

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

for
B-Cell Lymphoma, Myelodysplastic Syndromes (MDS),
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 12 - 70+

Code: NCT05092451

Phase1, Phase2, Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment

for
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Location: Houston TX
Sponsor: Taiho Oncology, Inc.

Sex: All

Age: 18+

Code: NCT04953897

Phase1, Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment

for
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Location: Houston TX
Sponsor: Taiho Oncology, Inc.

Sex: All

Age: 18+

Code: NCT04953910

Phase1, Recruiting

Tazemetostat and Palbociclib With CPX-351for R/R AML

for
Recurrent Acute Myeloid Leukemia,
Location: Philadelphia PA
Sponsor: Thomas Jefferson University

Sex: All

Age: 18+

Code: NCT05627232

Phase1, Recruiting

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ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

for
Acute Myelogenous Leukemia, Myelodysplastic Syndromes (MDS)
Location: New Haven CT, New York NY, Chapel Hill NC, Tampa FL,
Sponsor: Beijing InnoCare Pharma Tech Co., Ltd.

Sex: All

Age: 18+

Code: NCT06656494

Phase1, Recruiting

CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies

for
Acute Lymphoblastic Leukemia, Non-Hodgkin's Lymphoma,
Location: Ottawa, Vancouver
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18 - 70+

Code: NCT03765177

Phase1, Phase2, Recruiting

A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia (AML)
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05756777

Phase1, Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for
Hematologic Malignancies, Inherited Disorders of Metabolism,
Location: Boston MA, New Haven CT, Stony Brook NY, Lake Sucess NY,
Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All

Age: 0+

Code: NCT01351545

Recruiting

Metabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With CD19+ Relapsed/Refractory NHL, CLL/SLL

for
B-cell Non Hodgkin Lymphoma, Chronic Lymphocytic Leukemia
Location: Charleston SC
Sponsor: Medical University of South Carolina

Sex: All

Age: 18+

Code: NCT05702853

Phase1, Phase2, Recruiting

Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC

for
Leukemia, Inborn Errors of Metabolism,
Location: Philadelphia PA
Sponsor: Children's Hospital of Philadelphia

Sex: All

Age: 0 - 30

Code: NCT02356653

Early_phase1, Recruiting

Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma

for
Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18+

Code: NCT06839053

Phase2, Recruiting

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

for
Breast Cancer, Colorectal Cancer, Pancreas Cancer,
Location: Kingston, Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05403177

Recruiting

CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies

for
Recurrent B-Cell Non-Hodgkin Lymphoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT04892277

Phase1, Recruiting

CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia

for
Acute Myeloid Leukemia, Recurrent Adult Acute Myeloid Leukemia,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT05672147

Phase1, Recruiting

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

for
Central Nervous System Lymphoma,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05011045

Recruiting

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

for
Previously Untreated Relapsed Refractory Acute Myeloid Leukemia
Location: New York NY, Baltimore MD, Chapel Hill NC,
Sponsor: Beat AML, LLC

Sex: All

Age: 18+

Code: NCT03013998

Phase2, Phase3, Recruiting

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

for
Acute Myeloid Leukemia, Leukemia, Leukemia, Myeloid,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06138587

Phase1, Recruiting

Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

for
Acute Myeloid Leukemia, Essential Thrombocythemia,
Location: Seattle WA
Sponsor: University of Washington

Sex: All

Age: 18+

Code: NCT04282187

Phase2, Recruiting

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

for
B-Cell Non-Hodgkin Lymphoma,
Location: Jacksonville FL
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06191887

Phase1, Recruiting

What are clinical trials for leukemia?

Clinical trials for leukemia are research studies designed to evaluate new treatments, therapies, or diagnostic methods for different types of leukemia, a group of cancers that affect the blood and bone marrow. These trials aim to discover more effective ways to treat leukemia, manage its symptoms, and improve patient outcomes. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.

Why are leukemia clinical trials important?

Leukemia clinical trials are crucial because they drive advancements in treatment by testing new therapies, improving existing ones, and exploring novel approaches to manage and potentially cure the disease. These trials provide essential data on the safety and effectiveness of new treatments, which can lead to better outcomes and fewer side effects compared to current options.

Types of clinical trials for leukemia

Why participate in a leukemia clinical trial

Who can participate in a clinical trial for leukemia?

How to enroll in a leukemia clinical trial