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Leukemia Clinical Trials

Browse 1,314 Leukemia clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

for
Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04774393

Phase1, Phase2, Recruiting

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

for
AML, Childhood, Aml, Acute Myeloid Leukemia, Pediatric,
Location: St Louis MO
Sponsor: Washington University School of Medicine

Sex: All

Age: 18+

Code: NCT06158828

Phase1, Phase2, Recruiting

Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry

for
Multiple Myeloma, Amyloidosis, Plasma Cell Leukemia
Location: Birmingham AL
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 50+

Code: NCT05556928

Recruiting

Novel Digital Application for Patients With Acute Leukemia

for
Relapsed Adult Acute Myeloid Leukemia,
Location: Boston MA
Sponsor: Massachusetts General Hospital

Sex: All

Age: 18 - 70+

Code: NCT06472128

Recruiting

Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers

for
Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC)
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT04844528

Phase2, Recruiting

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Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

for
Hematologic Malignancies, Waldenstroms Macroglobulinaemia,
Location: Hackensack NJ, East Brunswick NJ, Montreal, Ottawa,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT04728893

Phase2, Recruiting

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Halifax, Portland ME, Scarborough ME, South Portland ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 59

Code: NCT05554393

Phase2, Recruiting

Early Integration of Palliative and Supportive Care in Cellular Therapy

for
Leukemia, Lymphoma, Multiple Myeloma, Blood Cancer,
Location: Calgary
Sponsor: Alberta Health Services, Calgary

Sex: All

Age: 18+

Code: NCT05190653

Recruiting

Factors Affecting Post-transplant Cyclophosphamide (PTCy) Efficacy

for
Leukemia, Not Otherwise Specified, Leukemia, Other
Location: Charlotte NC
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT03555851

Recruiting

Clinical Study of Anti-FLT3 CAR-T Cells for the Treatment of Relapsed/Refractory AML

for
Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)
Location: Houston TX
Sponsor: Hemogenyx Pharmaceuticals LLC

Sex: All

Age: 12+

Code: NCT06786533

Phase1, Recruiting

Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

for
Acute Bilineal Leukemia, Acute Biphenotypic Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03683433

Phase2, Recruiting

Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT)

for
Acute Leukemia, Acute Lymphoblastic Lymphoma
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 0+

Code: NCT06803745

Recruiting

Characterization of T-cell Repertoire in Patients With Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

for
Acute Myeloid Leukemia
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: All

Age: 18+

Code: NCT03921047

Recruiting

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

for
Leukemia, Lymphocytic, Chronic, B-Cell,
Location: Moncton, Sherbrooke, Albany NY, Greenfield Park,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT05947851

Phase3, Recruiting

Acute Myeloid Leukemia and Markers of Leukemia Stem Cells (CLL1 and CD45RA)

for
Acute Myeloid Leukemia
Location: Stony Brook NY
Sponsor: Suhu Liu

Sex: All

Age: 18+

Code: NCT06297551

Recruiting

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for
B Acute Lymphoblastic Leukemia Associated With Down Syndrome,
Location: Providence RI, New Haven CT, The Bronx NY,
Sponsor: Children's Oncology Group

Sex: All

Age: 6 - 39

Code: NCT05702645

Recruiting

Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Salt Lake City UT
Sponsor: University of Utah

Sex: All

Age: 18+

Code: NCT05183854

Phase2, Recruiting

Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study

for
Acute Myeloid Leukemia (AML)
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06811233

Phase2, Recruiting

Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01)

for
B-cell Acute Lymphoblastic Leukemia
Location: Boston MA, New York NY, Philadelphia PA, Buffalo NY,
Sponsor: Cellectis S.A.

Sex: All

Age: 15 - 50

Code: NCT04150497

Phase1, Phase2, Recruiting

HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML

for
Myeloid Malignancy, Acute Myeloid Leukemia,
Location: Minneapolis MN
Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All

Age: 18+

Code: NCT06594445

Phase1, Recruiting

What are clinical trials for leukemia?

Clinical trials for leukemia are research studies designed to evaluate new treatments, therapies, or diagnostic methods for different types of leukemia, a group of cancers that affect the blood and bone marrow. These trials aim to discover more effective ways to treat leukemia, manage its symptoms, and improve patient outcomes. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.

Why are leukemia clinical trials important?

Leukemia clinical trials are crucial because they drive advancements in treatment by testing new therapies, improving existing ones, and exploring novel approaches to manage and potentially cure the disease. These trials provide essential data on the safety and effectiveness of new treatments, which can lead to better outcomes and fewer side effects compared to current options.

Types of clinical trials for leukemia

Why participate in a leukemia clinical trial

Who can participate in a clinical trial for leukemia?

How to enroll in a leukemia clinical trial