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Leukemia Clinical Trials

Browse 1,314 Leukemia clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

for
CLL/SLL, Waldenstrom Macroglobulinemia, Follicular Lymphoma,
Location: Durham NC, Columbus OH, Cincinnati OH,
Sponsor: Newave Pharmaceutical Inc

Sex: All

Age: 18+

Code: NCT04775745

Phase1, Recruiting

Phase I/II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

for
Philadelphia Chromosome-Positive, Acute Lymphoblastic Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06308588

Phase1, Phase2, Recruiting

A Bilingual Virtually-based Intervention (PEDALL) for the Prevention of Weight Gain in Childhood ALL Patients Considering Key Genetic and Sociodemographic Risk Factors

for
Acute Lymphoblastic Leukemia, Obesity
Location: New York NY
Sponsor: Columbia University

Sex: All

Age: 5 - 21

Code: NCT05963971

Recruiting

Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

for
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
Location: New York NY, Atlanta GA
Sponsor: Meryx, Inc.

Sex: All

Age: 12+

Code: NCT04872478

Phase1, Recruiting

Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant

for
Hairy Cell Leukemia, Hairy Cell Leukemia Variant
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04815356

Phase1, Recruiting

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Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for
AML, AML With Mutated NPM1, Hematologic Malignancy, KMT2Ar,
Location: Boston MA, New Haven CT, Stony Brook NY,
Sponsor: Kura Oncology, Inc.

Sex: All

Age: 18+

Code: NCT06001788

Phase1, Recruiting

Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

for
Acute Myeloid Leukemia
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 50+

Code: NCT03586609

Phase2, Recruiting

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

for
Hypogammaglobulinemia, Bacterial Infections,
Location: Greenville NC, Bethesda MD, Morrisville NC,
Sponsor: Grifols Therapeutics LLC

Sex: All

Age: 18+

Code: NCT05645107

Phase3, Recruiting

CIML NK Cells With Venetoclax for AML

for
Acute Myeloid Leukemia, Acute Myeloid Leukemia Recurrent,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 18+

Code: NCT06152809

Phase1, Recruiting

Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia

for
Recurrent Acute Myeloid Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT03629171

Phase2, Recruiting

Mosaic Trial for Stem Cell Transplant Recipients

for
Hematologic Malignancy, Stem Cell Transplant,
Location: Nutley NJ, Washington D.C. DC, Chicago IL
Sponsor: Northwestern University

Sex: All

Age: 18+

Code: NCT06960993

Recruiting

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for
Hodgkin Lymphoma in Remission, Leukemia in Remission,
Location: Scarborough ME, Boston MA, Providence RI, New Haven CT,
Sponsor: Children's Oncology Group

Sex: All

Age: 0+

Code: NCT01790152

Recruiting

Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

for
Waldenstrom Macroglobulinemia, Lymphoplasmacytic Lymphoma,
Location: Bethesda MD
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All

Age: 18 - 70+

Code: NCT00923507

Recruiting

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

for
Acute Myeloid Leukemia, in Relapse,
Location: Winston-Salem NC, Charlotte NC, Houston TX
Sponsor: ARCE Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06680752

Phase1, Phase2, Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for
B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma,
Location: St. John's, Halifax, Bangor ME, Scarborough ME,
Sponsor: Children's Oncology Group

Sex: All

Age: 1 - 25

Code: NCT03959085

Phase3, Recruiting

Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT

for
Adult Acute Myeloid Leukemia
Location: Baltimore MD, Rochester NY, Tampa FL, Cleveland OH,
Sponsor: Priothera SAS

Sex: All

Age: 18 - 70+

Code: NCT05429632

Phase3, Recruiting

Co-administration of CART22-65s and huCART19 for B-ALL

for
B-cell Acute Lymphoblastic Leukemia,
Location: Philadelphia PA
Sponsor: Stephan Grupp MD PhD

Sex: All

Age: 0 - 29

Code: NCT05674175

Phase1, Phase2, Recruiting

A Study to Determine Number of Patients Who Develop High Ammonia Levels After Receiving Recombinant Erwinia Asparaginase

for
Hematopoietic and Lymphatic System Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 1+

Code: NCT06600659

Recruiting

CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML

for
Leukemia, Myeloid, Acute
Location: Philadelphia PA
Sponsor: University of Pennsylvania

Sex: All

Age: 18+

Code: NCT05945849

Phase1, Recruiting

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for
Acute Myeloid Leukemia
Location: Brunswick ME, Portland ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06317649

Phase2, Recruiting

What are clinical trials for leukemia?

Clinical trials for leukemia are research studies designed to evaluate new treatments, therapies, or diagnostic methods for different types of leukemia, a group of cancers that affect the blood and bone marrow. These trials aim to discover more effective ways to treat leukemia, manage its symptoms, and improve patient outcomes. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.

Why are leukemia clinical trials important?

Leukemia clinical trials are crucial because they drive advancements in treatment by testing new therapies, improving existing ones, and exploring novel approaches to manage and potentially cure the disease. These trials provide essential data on the safety and effectiveness of new treatments, which can lead to better outcomes and fewer side effects compared to current options.

Types of clinical trials for leukemia

Why participate in a leukemia clinical trial

Who can participate in a clinical trial for leukemia?

How to enroll in a leukemia clinical trial