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Leukemia Clinical Trials

Browse 1,314 Leukemia clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Study of Mogamulizumab to Prevent Adult T-cell Leukemia/Lymphoma in People With HTLV-1

for
T-Cell Leukemia/Lymphoma, Adult, T-cell Leukemia/Lymphoma,
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06698003

Phase2, Recruiting

Personalized NK Cell Therapy in CBT

for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 15 - 70+

Code: NCT02727803

Phase2, Recruiting

Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies

for
Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS,
Location: Baltimore MD, Washington D.C. DC
Sponsor: Catherine Bollard

Sex: All

Age: 0 - 70+

Code: NCT02203903

Phase1, Recruiting

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for
Acute Myeloid Leukemia,
Location: Halifax, Brunswick ME, Portland ME, Scarborough ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05564390

Phase2, Recruiting

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for
B-cell Acute Lymphoblastic Leukemia,
Location: Boston MA, New Haven CT, Valhalla NY, New York NY,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 0 - 25

Code: NCT06395103

Phase1, Phase2, Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Saint John, Damariscotta ME, Brunswick ME, Augusta ME,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT04269902

Phase3, Recruiting

A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia

for
Advanced Chronic Myeloid Leukemia,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT06401603

Phase1, Recruiting

Niclosamide in Pediatric Patients With Relapsed and Refractory AML

for
Acute Myeloid Leukemia (AML)
Location: Palo Alto CA
Sponsor: Stanford University

Sex: All

Age: 2 - 25

Code: NCT05188170

Phase1, Recruiting

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia,
Location: Halifax, Bangor ME, Scarborough ME, Boston MA,
Sponsor: PedAL BCU, LLC

Sex: All

Age: 0 - 22

Code: NCT04726241

Phase1, Phase2, Recruiting

A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)

for
Chronic Myelomonocytic Leukemia,
Location: Boston MA, Tampa FL, Rochester MN, Houston TX,
Sponsor: Solu Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06950034

Phase1, Recruiting

CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia

for
Acute Lymphoblastic Leukemia,
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT06847269

Phase2, Recruiting

Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia

for
Myelodysplastic Syndromes, Acute Myeloid Leukemia,
Location: Winnipeg
Sponsor: University of Manitoba

Sex: All

Age: 18+

Code: NCT06599762

Phase2, Recruiting

A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Azacitidine and Venetoclax, in Patients With Higher-risk Myeloproliferative Chronic Myelomonocytic Leukemia or Higher-risk Myelodysplastic Syndromes With Excess Blasts

for
Myelodysplastic Syndromes,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT05365035

Phase2, Recruiting

Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment

for
Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma,
Location: Portland OR
Sponsor: OHSU Knight Cancer Institute

Sex: All

Age: 18+

Code: NCT06784167

Recruiting

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

for
Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia,
Location: Houston TX
Sponsor: Baylor College of Medicine

Sex: All

Age: 0 - 70+

Code: NCT01853631

Phase1, Recruiting

Evaluate the Safety, Tolerability, Pharmacokinetic Profile, Efficacy of Bl-M11D1

for
Relapsed/Refractory Acute Myeloid Leukemia
Location: New Haven CT, Hackensack NJ, Philadelphia PA,
Sponsor: SystImmune Inc.

Sex: All

Age: 18+

Code: NCT06714591

Phase1, Recruiting

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for
Acute Myeloid Leukemia
Location: Halifax, Bangor ME, Scarborough ME, Boston MA,
Sponsor: Children's Oncology Group

Sex: All

Age: 0 - 21

Code: NCT04293562

Phase3, Recruiting

CD19x22 Chimeric Antigen Receptor T-cell Therapy (CAR T) in Pediatric B-ALL

for
B-cell Acute Lymphoblastic Leukemia
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 0 - 30

Code: NCT06559189

Phase1, Recruiting

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome,
Location: Boston MA, New Haven CT, Commack NY, Uniondale NY,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT06484062

Phase1, Recruiting

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

for
Acute Leukemia
Location: Boston MA, Providence RI, The Bronx NY, New York NY,
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 2+

Code: NCT04811560

Phase1, Phase2, Recruiting

What are clinical trials for leukemia?

Clinical trials for leukemia are research studies designed to evaluate new treatments, therapies, or diagnostic methods for different types of leukemia, a group of cancers that affect the blood and bone marrow. These trials aim to discover more effective ways to treat leukemia, manage its symptoms, and improve patient outcomes. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.

Why are leukemia clinical trials important?

Leukemia clinical trials are crucial because they drive advancements in treatment by testing new therapies, improving existing ones, and exploring novel approaches to manage and potentially cure the disease. These trials provide essential data on the safety and effectiveness of new treatments, which can lead to better outcomes and fewer side effects compared to current options.

Types of clinical trials for leukemia

Why participate in a leukemia clinical trial

Who can participate in a clinical trial for leukemia?

How to enroll in a leukemia clinical trial