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Leukemia Clinical Trials

Browse 1,314 Leukemia clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for
Acute Leukemia of Ambiguous Lineage,
Location: Scarborough ME, Boston MA, Providence RI, Worcester MA,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 0 - 1

Code: NCT06317662

Phase2, Recruiting

CLAG-GO for Patients With Persistent, Relapsed or Refractory AML

for
Acute Myeloid Leukemia, Adult, Acute Myeloid Leukemia Recurrent,
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT04050280

Phase2, Recruiting

Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

for
Leukemia
Location: Cincinnati OH
Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All

Age: 1 - 39

Code: NCT03826992

Phase1, Recruiting

Anti-CD7 CAR-T Cells in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia or Lymphoma

for
T-Cell Acute Lymphoblastic Leukemia/Lymphoma
Location: Philadelphia PA
Sponsor: Stephan Grupp MD PhD

Sex: All

Age: 0 - 29

Code: NCT06934382

Phase1, Recruiting

CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)

for
AML, Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
Location: Nashville TN, Houston TX, Denver CO, Sacramento CA
Sponsor: CERo Therapeutics Holdings, Inc.

Sex: All

Age: 18 - 70+

Code: NCT06834282

Phase1, Recruiting

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AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion

for
Acute Leukemia, Severe Aplastic Anemia, Non-hodgkin Lymphoma,
Location: Valhalla NY
Sponsor: Mitchell Cairo

Sex: All

Age: 0 - 30

Code: NCT04099966

Phase2, Recruiting

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

for
Acute Lymphoblastic Leukemia in Remission,
Location: Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT03670966

Phase1, Phase2, Recruiting

Study of Cordycepin Plus Pentostatin in Patients With Refractory TdT-Positive Leukemia

for
Refractory TdT-Positive Leukemia
Location: Boston MA, San Antonio TX
Sponsor: OncoVista, Inc.

Sex: All

Age: 18+

Code: NCT00709215

Phase1, Phase2, Recruiting

A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: New York NY, Houston TX, Duarte CA
Sponsor: Edgewood Oncology Inc.

Sex: All

Age: 18+

Code: NCT04243785

Phase1, Recruiting

Treatment of Hematologic Malignancies With Single-Unit or Double-Unit Cord Blood Transplantation

for
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
Location: Denver CO
Sponsor: Colorado Blood Cancer Institute

Sex: All

Age: 18 - 49

Code: NCT00328237

Phase2, Recruiting

Oral Adherence in Hematological Oncology Agents and Impact on Comorbid Therapy Adherence

for
Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia,
Location: Nashville TN
Sponsor: University of Tennessee

Sex: All

Age: 18+

Code: NCT04663100

Recruiting

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for
Hematologic Malignancy, AML, ALL, BPDCN, MDS,
Location: New York NY, Washington DC, Ann Arbor MI, Cincinnati OH,
Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All

Age: 1 - 21

Code: NCT05476770

Phase1, Recruiting

Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies

for
Acute Myeloid Leukemia, B-cell Acute Lymphoblastic Leukemia,
Location: Cincinnati OH, Birmingham AL, Nashville TN, Houston TX,
Sponsor: Vincerx Pharma, Inc.

Sex: All

Age: 18+

Code: NCT06034275

Phase1, Recruiting

Study of NRX 195183 Therapy for Patients With Relapsed or Refractory Acute Promyelocytic Leukemia

for
Acute Promyelocytic Leukemia
Location: Santa Monica, CA
Sponsor: NuRx Pharmaceuticals, Inc.

Sex: All

Age: 18+

Code: NCT00675870

Phase2, Recruiting

Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)

for
Chronic Lymphocytic Leukemia, CLL, Untreated, Front-line,
Location: Boston MA, New Hyde Park NY, Houston TX, La Jolla CA
Sponsor: Chronic Lymphocytic Leukemia Research Consortium

Sex: All

Age: 0+

Code: NCT00628238

Phase2, Recruiting

Trial of Cladribine, Cytarabine, Mitoxantrone, Filgrastim (CLAG-M) in Relapsed Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma,
Location: Valhalla NY
Sponsor: New York Medical College

Sex: All

Age: 0+

Code: NCT01513603

Phase2, Recruiting

KRT-232 and TKI Study in Chronic Myeloid Leukemia

for
Chronic Myeloid Leukemia
Location: Toronto, Pittsburgh PA, Augusta GA, Birmingham AL,
Sponsor: Kartos Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT04835584

Phase1, Phase2, Recruiting

Bright Ideas - CIN Feasibility Study

for
Acute Lymphoblastic Leukemia (ALL)
Location: New Brunswick NJ, Falls Church VA, Toronto,
Sponsor: The Hospital for Sick Children

Sex: All

Age: 4 - 18

Code: NCT04929899

Recruiting

Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia

for
Acute Lymphoblastic Leukemia, Hepatotoxicity
Location: Orange CA
Sponsor: Children's Hospital of Orange County

Sex: All

Age: 5 - 29

Code: NCT05501899

Early_phase1, Recruiting

A PALG Prospective Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) and Two Standard Salvage Regimens (FLAG-IDA vs CLAG-M) in AML Patients ≤ 60 Years Old

for
Acute Myeloid Leukemia
Location: New York NY
Sponsor: Polish Adult Leukemia Group

Sex: All

Age: 18 - 60

Code: NCT03257241

Phase3, Recruiting

What are clinical trials for leukemia?

Clinical trials for leukemia are research studies designed to evaluate new treatments, therapies, or diagnostic methods for different types of leukemia, a group of cancers that affect the blood and bone marrow. These trials aim to discover more effective ways to treat leukemia, manage its symptoms, and improve patient outcomes. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.

Why are leukemia clinical trials important?

Leukemia clinical trials are crucial because they drive advancements in treatment by testing new therapies, improving existing ones, and exploring novel approaches to manage and potentially cure the disease. These trials provide essential data on the safety and effectiveness of new treatments, which can lead to better outcomes and fewer side effects compared to current options.

Types of clinical trials for leukemia

Why participate in a leukemia clinical trial

Who can participate in a clinical trial for leukemia?

How to enroll in a leukemia clinical trial