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Oncology Clinical Trials

Browse 9,232 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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1

Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients

for
End Stage Renal Disease, Hypertension,
Location: Dallas TX
Sponsor: VA Office of Research and Development

Sex: All

Age: 18+

Code: NCT04163614

Recruiting

Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

for
Colorectal Cancer, Early Onset Colorectal Cancer, Diet Habit,
Location: Chicago IL, Denver CO
Sponsor: San Raffaele University

Sex: All

Age: 18 - 49

Code: NCT05732623

Recruiting

PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer

for
Prostate Cancer, Prostate Adenocarcinoma,
Location: Miami FL
Sponsor: University of Miami

Sex: Male

Age: 18+

Code: NCT06392295

Phase2, Recruiting

Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial

for
Locally Advanced Bladder Urothelial Carcinoma,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06764095

Recruiting

Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

for
Gastric Cancers
Location: Chicago IL
Sponsor: University of Chicago

Sex: All

Age: 0+

Code: NCT01416714

Recruiting

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Patient-Centered Communication of Life Expectancy Estimates in Genitourinary Malignancies

for
Prostate Cancer Stage I, Kidney Cancer Stage I,
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT03522155

Recruiting

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

for
Prostate Cancer,
Location: Bala-Cynwyd PA, Towson MD, Myrtle Beach SC,
Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male

Age: 18+

Code: NCT04729114

Phase1, Recruiting

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for
Advanced Melanoma
Location: Boston MA, Lake Success NY, Hackensack NJ,
Sponsor: Immunocore Ltd

Sex: All

Age: 18+

Code: NCT06112314

Phase3, Recruiting

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

for
Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum,
Location: Cleveland OH
Sponsor: Case Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT04624555

Recruiting

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

for
Metastatic Colorectal Cancer (Mcrc),
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05286814

Phase2, Recruiting

Role of Gut Microbiome in Cancer Therapy

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT05112614

Recruiting

Collection of Blood for Multiple Collaborative Studies

for
HIV
Location: San Francisco CA
Sponsor: University of California, San Francisco

Sex: All

Age: 18+

Code: NCT01336855

Recruiting

Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel

for
Pancreatic Adenocarcinoma, Metastatic Pancreatic Cancer,
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06483555

Phase1, Phase2, Recruiting

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-159642 in Participants With Advanced Solid Tumors

for
Advanced Solid Tumors
Location: Fairfax VA, Grand Rapids MI, Irving TX, Austin TX,
Sponsor: Vividion Therapeutics, Inc.

Sex: All

Age: 18+

Code: NCT06804824

Phase1, Recruiting

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

for
Myelodysplastic Syndromes, Acute Myeloid Leukemia,
Location: St. John's, Boston MA, New Haven CT, Mineola NY,
Sponsor: Taiho Oncology, Inc.

Sex: All

Age: 18+

Code: NCT04256317

Phase2, Phase3, Recruiting

Evaluation of Pirfenidone as a Novel Therapeutic Strategy Against Recurrent Acute Pancreatitis.

for
Recurrent Acute Pancreatitis
Location: Birmingham AL, Iowa City IA, Rochester MN
Sponsor: University of Alabama at Birmingham

Sex: All

Age: 18 - 70+

Code: NCT06253117

Phase2, Recruiting

HIPEC After Initial CRS in Patients Who Have Received NACT

for
Ovarian Cancer, Fallopian Tube Cancer,
Location: New Hyde Park NY
Sponsor: Northwell Health

Sex: Female

Age: 18 - 70+

Code: NCT03540017

Phase1, Recruiting

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

for
Thyroid Cancer
Location: Bethesda MD
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All

Age: 18 - 70+

Code: NCT03841617

Phase2, Recruiting

Feasibility of Remote Activity Assessment and PRO Collection Among Transgender Cancer Survivors

for
Neoplasms, Chronic Disease
Location: Los Angeles CA
Sponsor: Cedars-Sinai Medical Center

Sex: All

Age: 18+

Code: NCT05391217

Recruiting

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

for
Ovarian Cancer, Pancreas Cancer, Urothelial Carcinoma,
Location: New York NY, Rochester NY, Atlanta GA, Denver CO,
Sponsor: Nammi Therapeutics Inc

Sex: All

Age: 18+

Code: NCT06582017

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer