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Oncology Clinical Trials

Browse 9,252 oncology clinical trials enrolling across the United States and Canada. 214 people applied to oncology studies last month. Search by city or state to find one near you.

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Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

for
Cholangiocarcinoma
Location: Charlottesville VA, Orlando FL, Tampa FL, Chicago IL,
Sponsor: Genfit

Sex: All

Age: 18+

Code: NCT05874414

Phase 1, Phase 2, Recruiting

Non-invasive Liquid Biopsy Analysis of Epigenomics Signatures in Multiple Cancer Types

for
Diagnosis of Cancer of Various Organs
Location: San Diego CA
Sponsor: ClearNote Health

Sex: All

Age: 21 - 70+

Code: NCT03869814

Recruiting

A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer
Location: New York City NY, Louisville KY, Nashville TN, Omaha NE,
Sponsor: Avistone Biotechnology Co., Ltd.

Sex: All

Age: 18+

Code: NCT06046495

Phase 1, Recruiting

Precision Medicine Approaches to Renal Osteodystrophy

for
Renal Osteodystrophy, Chronic Kidney Diseases, CKD-MBD,
Location: St Louis MO
Sponsor: Thomas Nickolas

Sex: All

Age: 18+

Code: NCT05880914

Recruiting

Study of APR-1051 in Patients With Advanced Solid Tumors

for
Advanced Solid Tumor
Location: New Brunswick NJ, Fairfax VA, Cleveland OH, Houston TX,
Sponsor: Aprea Therapeutics

Sex: All

Age: 18+

Code: NCT06260514

Phase 1, Recruiting

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Cetuximab, Cisplatin, and Radiotherapy in Women With Locally Advanced Cervical Carcinoma

for
Cancer of the Cervix
Location: Charlottesville VA
Sponsor: University of Virginia

Sex: Female

Age: 18+

Code: NCT00292955

Phase 2, Recruiting

Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors

for
Digestive System Neuroendocrine Tumor G1,
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06016855

Recruiting

A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer

for
Prostate Cancer, Radiation Toxicity, Urinary Complication
Location: Rochester NY
Sponsor: University of Rochester

Sex: Male

Age: 18 - 70

Code: NCT05530655

Early Phase 1, Recruiting

Pioglitazone Therapy Targeting Fatigue in Breast Cancer

for
Breast Cancer, Muscle Fatigue
Location: Morgantown WV
Sponsor: West Virginia University

Sex: Female

Age: 18+

Code: NCT05013255

Phase 2, Recruiting

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

for
Castration-Resistant Prostate Carcinoma,
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: Male

Age: 18+

Code: NCT06616155

Phase 1, Phase 2, Recruiting

Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms

for
Myeloproliferative Neoplasm
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05074355

Phase 2, Recruiting

Pilot Imaging Study of Leukemia

for
Acute Lymphocytic Leukemia, Acute Myeloid Leukemia,
Location: Oklahoma City OK
Sponsor: University of Oklahoma

Sex: All

Age: 4 - 70+

Code: NCT03633955

Phase 1, Recruiting

Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma

for
Glioblastoma
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 0+

Code: NCT04863950

Phase 2, Recruiting

Preoperative Nicotine Cessation for Women With Breast Cancer Recommended for Reconstruction

for
Breast Cancer
Location: Gainesville FL
Sponsor: University of Florida

Sex: Female

Age: 18 - 70+

Code: NCT06461650

Recruiting

Peri-implant Mucosal Changes Over Time Following Implant Provisional Removal in the Esthetic Zone

for
Tooth Loss, Implant Site Reaction
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: All

Age: 18+

Code: NCT06783595

Recruiting

International Pediatric Adrenocortical Tumor Registry

for
Adrenocortical Tumor
Location: Dayton OH, Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT00700414

Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

for
Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06342414

Recruiting

Perioperative Mindfulness Proposal

for
Breast Cancer, DCIS
Location: Newport Beach CA
Sponsor: Hoag Memorial Hospital Presbyterian

Sex: Female

Age: 18+

Code: NCT04049214

Recruiting

The Clonal Hematopoiesis & Inflammation in Vasculature Registry and Biorepository

for
Clonal Hematopoiesis
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06701214

Recruiting

Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for
Ovarian Cancer, Fallopian Tube, Primary Peritoneal Cancer
Location: Richmond VA, Pittsburgh PA, Columbus OH, Birmingham AL,
Sponsor: University of Alabama at Birmingham

Sex: Female

Age: 18+

Code: NCT04606914

Phase 2, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer