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Oncology Clinical Trials

Browse 9,232 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer

for
Prostate Cancer, Radiation Toxicity, Urinary Complication
Location: Rochester NY
Sponsor: University of Rochester

Sex: Male

Age: 18 - 70

Code: NCT05530655

Early_phase1, Recruiting

Pioglitazone Therapy Targeting Fatigue in Breast Cancer

for
Breast Cancer, Muscle Fatigue
Location: Morgantown WV
Sponsor: West Virginia University

Sex: Female

Age: 18+

Code: NCT05013255

Phase2, Recruiting

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

for
Castration-Resistant Prostate Carcinoma,
Location: Ann Arbor MI
Sponsor: University of Michigan Rogel Cancer Center

Sex: Male

Age: 18+

Code: NCT06616155

Phase1, Phase2, Recruiting

Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms

for
Myeloproliferative Neoplasm
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: All

Age: 18+

Code: NCT05074355

Phase2, Recruiting

Pilot Imaging Study of Leukemia

for
Acute Lymphocytic Leukemia, Acute Myeloid Leukemia,
Location: Oklahoma City OK
Sponsor: University of Oklahoma

Sex: All

Age: 4 - 70+

Code: NCT03633955

Phase1, Recruiting

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Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma

for
Glioblastoma
Location: San Antonio TX
Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All

Age: 0+

Code: NCT04863950

Phase2, Recruiting

Preoperative Nicotine Cessation for Women With Breast Cancer Recommended for Reconstruction

for
Breast Cancer
Location: Gainesville FL
Sponsor: University of Florida

Sex: Female

Age: 18 - 70+

Code: NCT06461650

Recruiting

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

for
Metastatic Colorectal Cancer
Location: Trenton NJ, Montreal, Baltimore MD, Washington D.C. DC,
Sponsor: AstraZeneca

Sex: All

Age: 18 - 70+

Code: NCT06792695

Phase2, Recruiting

Peri-implant Mucosal Changes Over Time Following Implant Provisional Removal in the Esthetic Zone

for
Tooth Loss, Implant Site Reaction
Location: Loma Linda CA
Sponsor: Loma Linda University

Sex: All

Age: 18+

Code: NCT06783595

Recruiting

International Pediatric Adrenocortical Tumor Registry

for
Adrenocortical Tumor
Location: Dayton OH, Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 21

Code: NCT00700414

Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

for
Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma,
Location: Duarte CA
Sponsor: City of Hope Medical Center

Sex: All

Age: 18+

Code: NCT06342414

Recruiting

Perioperative Mindfulness Proposal

for
Breast Cancer, DCIS
Location: Newport Beach CA
Sponsor: Hoag Memorial Hospital Presbyterian

Sex: Female

Age: 18+

Code: NCT04049214

Recruiting

The Clonal Hematopoiesis & Inflammation in Vasculature Registry and Biorepository

for
Clonal Hematopoiesis
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT06701214

Recruiting

Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for
Ovarian Cancer, Fallopian Tube, Primary Peritoneal Cancer
Location: Richmond VA, Pittsburgh PA, Columbus OH, Birmingham AL,
Sponsor: University of Alabama at Birmingham

Sex: Female

Age: 18+

Code: NCT04606914

Phase2, Recruiting

Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC

for
Non-small Cell Lung Cancer(NSCLC),
Location: Fairfax VA
Sponsor: LG Chem

Sex: All

Age: 18+

Code: NCT06332755

Phase1, Recruiting

Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

for
Advanced Solid Tumor, Cutaneous Tumor, Subcutaneous Tumor,
Location: Boston MA, Bethesda MD, Toronto, Pittsburgh PA,
Sponsor: Ankyra Therapeutics, Inc

Sex: All

Age: 18+

Code: NCT06171750

Phase1, Recruiting

Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition

for
Relapsing-remitting Multiple Sclerosis,
Location: Los Angeles CA
Sponsor: University of California, Los Angeles

Sex: Female

Age: 18 - 55

Code: NCT01466114

Phase2, Recruiting

A Study of JNJ-87890387 for Advanced Solid Tumors

for
Neoplasms, Advanced Solid Tumors
Location: Grand Rapids MI, Nashville TN
Sponsor: Janssen Research & Development, LLC

Sex: All

Age: 18+

Code: NCT06178614

Phase1, Recruiting

Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma

for
Oropharyngeal Squamous Cell Carcinoma
Location: Charleston SC, Jacksonville FL, Gainesville FL
Sponsor: University of Florida

Sex: All

Age: 18+

Code: NCT05268614

Phase2, Recruiting

A Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-Up

for
Allergy, Sinus Disorders, Atopic Diseases, Asthma, Allergic Rhinitis, Atopic Dermatitis, EoE, Drug a,
Location: Bethesda MD
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All

Age: 3 - 70+

Code: NCT06732414

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer