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Oncology Clinical Trials

Browse 9,232 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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1

PSB202 in Patients With Previously Treated-, Relapsed-, Indolent B-Cell Malignancies

for
Follicular Lymphoma,
Location: Louisville KY
Sponsor: Qilu Puget Sound Biotherapeutics (dba Sound Biologics)

Sex: All

Age: 18+

Code: NCT05003141

Phase1, Recruiting

Emapalumab Prevention of CAR-T Cell Associated Toxicities

for
Large B-cell Lymphoma, Relapsed Non-Hodgkin Lymphoma,
Location: Boston MA
Sponsor: Marcela V. Maus, M.D.,Ph.D.

Sex: All

Age: 18+

Code: NCT06550141

Phase2, Recruiting

Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Rochester MN, Scottsdale AZ
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT03516617

Phase2, Recruiting

Advanced Wireless Sensors for Neonatal Care in the Delivery Room

for
Sudden Unexplained Infant Death, Apnea of Newborn,
Location: Montreal
Sponsor: Guilherme Sant'Anna, MD

Sex: All

Age: 0

Code: NCT06693817

Recruiting

Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC

for
NSCLC Stage IV, ALK Fusion Protein Expression
Location: Baltimore MD
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All

Age: 18+

Code: NCT05950139

Phase1, Phase2, Recruiting

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MRI-Guided Cryoablation for Focal Native Prostate Cancer

for
Primary Malignant Neoplasm of Prostate (Diagnosis)
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: Male

Age: 30 - 70+

Code: NCT04797039

Recruiting

Finding the Cause for Post-Transplant Diabetes Mellitus After Allogeneic Hematopoietic Cell Transplant

for
Diabetes Mellitus, Cancer
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18 - 70+

Code: NCT03415139

Recruiting

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for
AL Amyloidosis
Location: Boston MA, Guilford CT, Hartford CT, North Haven CT,
Sponsor: SWOG Cancer Research Network

Sex: All

Age: 18+

Code: NCT06022939

Phase3, Recruiting

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

for
Clinical Stage III Cutaneous Melanoma AJCC v8,
Location: Mineola NY, New York NY, Baltimore MD,
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18+

Code: NCT05896839

Phase1, Phase2, Recruiting

Safety and Performance of the Multi-Modal UltraSound Tomography (MUST) Device in Breast Cancer Screening

for
Breast Cancer Screening
Location: Boston MA
Sponsor: Transonic Imaging, Inc.

Sex: Female

Age: 40 - 70+

Code: NCT04102722

Recruiting

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

for
Advanced Metastatic Castration-resistant Prostate Cancer,
Location: Sherbrooke, Montreal, Toronto, Hamilton, Vancouver
Sponsor: Bayer

Sex: All

Age: 18+

Code: NCT06217822

Phase1, Recruiting

Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors

for
Advanced Solid Tumor, Malignant Solid Tumor
Location: Hackensack NJ, Sarasota FL, Denver CO
Sponsor: Daiichi Sankyo

Sex: All

Age: 18+

Code: NCT04145622

Phase1, Phase2, Recruiting

A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

for
Multiple Myeloma, Monoclonal Gammopathy of Renal Significance
Location: Commack NY, Uniondale NY, Harrison NY, New York NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06083922

Phase2, Recruiting

To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET Dysregulation

for
Advanced Solid Tumors
Location: Orange City FL, Lake City FL, Houston TX
Sponsor: Abion Inc

Sex: All

Age: 18+

Code: NCT05541822

Phase2, Recruiting

Patient Preferences for Barrett's Esophagus and Esophageal Cancer Screening Tests

for
Gastro Esophageal Reflux Disease, Barrett Esophagus
Location: Aurora CO
Sponsor: University of Colorado, Denver

Sex: All

Age: 18 - 70+

Code: NCT06693622

Recruiting

Breast Cancer Endocrine Therapy FITness (BE-FIT) Trial.

for
Breast Neoplasms
Location: Vancouver
Sponsor: University of British Columbia

Sex: Female

Age: 19 - 70+

Code: NCT04824339

Recruiting

Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi

for
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Location: Columbus OH
Sponsor: Kerry Rogers

Sex: All

Age: 18+

Code: NCT06466122

Phase2, Recruiting

Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps

for
Colorectal Carcinoma
Location: Los Angeles CA
Sponsor: Jonsson Comprehensive Cancer Center

Sex: All

Age: 21+

Code: NCT06376565

Recruiting

Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

for
Small-cell Lung Cancer, Small Cell Lung Carcinoma
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18+

Code: NCT05450965

Phase2, Recruiting

Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors

for
Human Immunodeficiency Virus, End Stage Renal Disease
Location: Metairie LA
Sponsor: Tulane University

Sex: All

Age: 18+

Code: NCT05159466

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer