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Oncology Clinical Trials

Browse 8,122 oncology clinical trials enrolling across the United States and Canada. 214 people applied to oncology studies last month. Search by city or state to find one near you.

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Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02

for
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Location: Fairway KS
Sponsor: Celyad Oncology SA

Sex: All

Age: 18+

Code: NCT04167696

Phase 1, Recruiting

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

for
Ankylosing Spondylitis, Autoimmune Disease, Crohn Disease,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04751396

Recruiting

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8,
Location: Atlanta GA
Sponsor: Emory University

Sex: All

Age: 18+

Code: NCT06662058

Recruiting

Diphencyprone Plus Immune Checkpoint Inhibition in the Treatment of Cutaneous Metastases

for
Cutaneous Metastases
Location: New York NY
Sponsor: Nicholas Gulati

Sex: All

Age: 18+

Code: NCT05481658

Phase 1, Recruiting

Two Fraction Prostate SBRT With DIL SIB

for
Prostate Cancer
Location: Mineola NY, New York NY
Sponsor: NYU Langone Health

Sex: Male

Age: 18+

Code: NCT05864196

Phase 1, Recruiting

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Family Study of Lymphoproliferative Disorders

for
Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell,
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18 - 70+

Code: NCT00626496

Recruiting

Axitinib and Nivolumab for the Treatment of Mucosal Melanoma

for
Mucosal Melanoma
Location: Harrison NY, New York NY
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT05384496

Phase 2, Recruiting

Radiation OmisSion in PAtients With CLinically Node Negative Breast Cancer Undergoing Lumpectomy

for
Breast Cancer
Location: Quebec, Trois-Rivieres, Montreal,
Sponsor: Ontario Clinical Oncology Group (OCOG)

Sex: Female

Age: 50+

Code: NCT05866458

Recruiting

A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand

for
HSIL, High Grade Squamous Intraepithelial Lesions, Anal Cancer,
Location: New York NY
Sponsor: Stephen E. Goldstone

Sex: All

Age: 18 - 70+

Code: NCT03302858

Phase 2, Recruiting

Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED)

for
Pancreatic Cancer, Hepatocellular Cancer, Biliary Tract Cancer,
Location: Edmonton
Sponsor: AHS Cancer Control Alberta

Sex: All

Age: 18+

Code: NCT05451043

Phase 2, Recruiting

Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer

for
Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8,
Location: Nashville TN
Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All

Age: 18+

Code: NCT05501665

Phase 1, Phase 2, Recruiting

VST-1001 (Dilute Fluorescein) for Lymphatic Mapping & Localization of Lymph Nodes in Patients With Breast Cancer

for
Breast Cancer
Location: Houston TX, Salt Lake City UT
Sponsor: Vestan, Inc.

Sex: All

Age: 18+

Code: NCT02294565

Phase 1, Phase 2, Recruiting

A Pilot Study To Evaluate the Effectiveness of Pulsed Time-Domain Optical Spectroscopy for Monitoring the Responses in Neoadjuvant Treatments of Locally-Advanced Breast Cancer

for
Breast Cancer
Location: Toronto
Sponsor: Sunnybrook Health Sciences Centre

Sex: Female

Age: 20 - 70+

Code: NCT00438074

Recruiting

A Study Collecting Health Information to Understand and Prevent Gastric Cancer

for
Gastric Atrophy, Gastric Intestinal Metaplasia, Dysplasia,
Location: Commack NY, Rockville Centre NY, Harrison NY,
Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All

Age: 18+

Code: NCT06370143

Recruiting

Effectiveness of Central Oncology Navigation and the Use of an ORN

for
Cancer, Malignant Tumor
Location: Chapel Hill NC
Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All

Age: 18+

Code: NCT06618274

Recruiting

Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant App

for
Malignant Skin Neoplasm, Melanoma
Location: Rochester MN
Sponsor: Mayo Clinic

Sex: All

Age: 18+

Code: NCT06675643

Recruiting

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

for
Triple-Negative Breast Cancer
Location: Halifax, Moncton, Rimouski, Farmington CT, New Haven CT,
Sponsor: Merck Sharp & Dohme LLC

Sex: All

Age: 18+

Code: NCT06393374

Phase 3, Recruiting

Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

for
Melanoma
Location: Memphis TN
Sponsor: St. Jude Children's Research Hospital

Sex: All

Age: 0 - 18

Code: NCT02775643

Recruiting

Safety Study of Camptothecin-20-O-Propionate Hydrate (CZ48)

for
Malignant Lymphoma of Extranodal and/or Solid Organ Site,
Location: San Antonio TX
Sponsor: Cao Pharmaceuticals Inc.

Sex: All

Age: 18+

Code: NCT02575638

Phase 1, Recruiting

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery

for
Anatomic Stage 0 Breast Cancer AJCC v8,
Location: Los Angeles CA
Sponsor: University of Southern California

Sex: Female

Age: 18+

Code: NCT06297265

Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer