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Oncology Clinical Trials

Browse 8,863 oncology clinical trials enrolling across the United States and Canada. Search by city or state to find one near you.

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St. Paul's Advanced Resection Center Cohort for Colorectal Neoplasia (SPARC-C)

for
Colon Adenoma, Colon Polyp, Colon Lesion
Location: Saint Cloud MN, Vancouver
Sponsor: University of British Columbia

Sex: All

Age: 18+

Code: NCT05402696

Recruiting

Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors

for
Glioblastoma, WHO Grade II Glioma, WHO Grade III Glioma
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT04479696

Recruiting

Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure

for
Hematopoietic and Lymphoid Cell Neoplasm,
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 18+

Code: NCT02464696

Recruiting

Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)

for
Viral Infection, Primary Immune Deficiency Disorder
Location: Vallhala NY, Philadelphia PA, Baltimore MD, Columbus OH,
Sponsor: New York Medical College

Sex: All

Age: 0 - 70+

Code: NCT04197596

Phase1, Phase2, Recruiting

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

for
Cancer Risk, Cancer Predisposition Syndrome,
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 0+

Code: NCT05463796

Recruiting

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R-RPLND as First-line Treatment for Clinical Stage IIA/B Testicular Seminoma

for
Lymphadenopathy Retroperitoneal, Stage II Testicular Seminoma
Location: Toronto
Sponsor: University Health Network, Toronto

Sex: Male

Age: 18+

Code: NCT05345158

Recruiting

Virtual Reality Therapy for Cancer-Treatment Associated Symptoms

for
Cancer, Cancer Pain, Virtual Reality
Location: Baltimore MD
Sponsor: University of Maryland, Baltimore

Sex: All

Age: 18 - 70+

Code: NCT06248216

Recruiting

Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

for
Acute Leukemia, Acute Lymphoblastic Leukemia,
Location: Pittsburgh PA, Tampa FL, Seattle WA
Sponsor: Fred Hutchinson Cancer Center

Sex: All

Age: 1 - 60

Code: NCT03970096

Phase2, Recruiting

Cancer and Mild Cognitive Impairment Dyadic Intervention

for
Cancer, Cognitive Impairment
Location: Durham NC
Sponsor: Duke University

Sex: All

Age: 18 - 70+

Code: NCT05144516

Recruiting

Taste Alterations Study

for
Chemotherapy Side Effects, Taste, Altered
Location: Chicago IL
Sponsor: Wake Forest University Health Sciences

Sex: All

Age: 18+

Code: NCT06669416

Recruiting

Pilot Study Dara-CyBorD in Newly Diagnosed Multiple Myeloma Patients With Renal Failure

for
Multiple Myeloma, Renal Failure
Location: Augusta GA
Sponsor: Augusta University

Sex: All

Age: 18 - 70+

Code: NCT06142396

Early_phase1, Recruiting

Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALL

for
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Location: Tampa FL
Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All

Age: 18+

Code: NCT07250087

Phase1, Recruiting

Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck

for
Squamous Cell Carcinoma of Head and Neck
Location: Boston MA
Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All

Age: 18+

Code: NCT06744296

Recruiting

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for
Breast Cancer
Location: Boston MA, New Haven CT, Stony Brook NY, New York NY,
Sponsor: Greenwich LifeSciences, Inc.

Sex: All

Age: 18 - 70+

Code: NCT05232916

Phase3, Recruiting

Intensive Cancer Screening After Cryptogenic Stroke

for
Occult Cancer
Location: Ottawa
Sponsor: Ottawa Hospital Research Institute

Sex: All

Age: 18+

Code: NCT05733416

Recruiting

Geriatric Thoracic Surgery Ambulation Challenge

for
Thoracic Diseases, Surgery, Therapy, Exercise
Location: Boston MA
Sponsor: Dana-Farber Cancer Institute

Sex: All

Age: 65+

Code: NCT04630496

Recruiting

Hydrus® Microstent New Enrollment Post-Approval Study

for
Primary Open Angle Glaucoma
Location: Southern Pines NC, Fraser MI, Cincinnati OH, Kenosha WI,
Sponsor: Alcon Research

Sex: All

Age: 45+

Code: NCT04553523

Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

for
Glioblastoma, High-grade Glioma, Glioblastoma, IDH-wildtype,
Location: Boston MA, San Francisco CA
Sponsor: Jasper Gerritsen

Sex: All

Age: 18 - 70+

Code: NCT06118723

Recruiting

CPRIT: Patient Adherence to Lung Cancer Screening

for
Lung Cancer Screening
Location: Houston TX
Sponsor: M.D. Anderson Cancer Center

Sex: All

Age: 50 - 70+

Code: NCT06872723

Recruiting

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

for
Diffuse Large Cell Lymphoma, Non-Hodgkin Lymphoma,
Location: Bethesda MD
Sponsor: National Cancer Institute (NCI)

Sex: All

Age: 18 - 70+

Code: NCT05389423

Phase1, Recruiting

What is oncology?

Oncology is the branch of medicine focused on cancer. Cancer itself is not a single disease. It is a family of more than 100 diseases, from breast cancer and lung cancer to blood cancers like leukemia and lymphoma. What they share is the same basic problem: cells that grow and divide without stopping. About 4 in 10 people in the US will be diagnosed with some form of cancer during their lifetime.

Cancer research moves faster than almost any other field of medicine. Cancer drugs made up about 35% of all new FDA drug approvals in 2025, 16 new medicines in one year. The 5 year survival rate for all cancers combined reached 70% for people diagnosed in 2015 to 2021, a first in US history. And survival for metastatic (spread) cancer has doubled since the mid 1990s, from 17% to 35%. Every one of those gains came through clinical trials.

Who can participate in oncology trials?

Do oncology trial participants get paid?

Types of cancer clinical trials

The stages of cancer, and why they matter for trials

How to enroll in a clinical trial for cancer